-
1
-
-
13144258732
-
Twenty proteins containing a C-terminal SOCS box form five structural classes
-
Hilton DJ, Richardson RT, Alexander WS et al. Twenty proteins containing a C-terminal SOCS box form five structural classes. Proc Natl Acad Sci USA 1998 95 : 114 9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 114-9
-
-
Hilton, D.J.1
Richardson, R.T.2
Alexander, W.S.3
-
2
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989 7 : 145 73.
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 145-73
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
3
-
-
0028201726
-
Acquisition of lymphokine-producing phenotype by CD4+ T cells
-
Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994 12 : 635 73.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 635-73
-
-
Seder, R.A.1
Paul, W.E.2
-
4
-
-
0030764961
-
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
-
Zhang DH, Cohn L, Ray P, Bottomly K, Ray A. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem 1997 272 : 21597 603.
-
(1997)
J Biol Chem
, vol.272
, pp. 21597-603
-
-
Zhang, D.H.1
Cohn, L.2
Ray, P.3
Bottomly, K.4
Ray, A.5
-
5
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997 89 : 587 96.
-
(1997)
Cell
, vol.89
, pp. 587-96
-
-
Zheng, W.1
Flavell, R.A.2
-
6
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000 100 : 655 69.
-
(2000)
Cell
, vol.100
, pp. 655-69
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
7
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux H, O'Garra A, Bigler M et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997 389 : 737 42.
-
(1997)
Nature
, vol.389
, pp. 737-42
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
-
8
-
-
2942685507
-
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
-
Akdis M, Verhagen J, Taylor A et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 2004 199 : 1567 75.
-
(2004)
J Exp Med
, vol.199
, pp. 1567-75
-
-
Akdis, M.1
Verhagen, J.2
Taylor, A.3
-
9
-
-
0038434099
-
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
-
Gambineri E, Torgerson TR, Ochs HD. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol 2003 15 : 430 5.
-
(2003)
Curr Opin Rheumatol
, vol.15
, pp. 430-5
-
-
Gambineri, E.1
Torgerson, T.R.2
Ochs, H.D.3
-
10
-
-
0036533474
-
Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: Implications for Th cell lineage commitment and maintenance
-
Egwuagu CE, Yu CR, Zhang M, Mahdi RM, Kim SJ, Gery I. Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance. J Immunol 2002 168 : 3181 7.
-
(2002)
J Immunol
, vol.168
, pp. 3181-7
-
-
Egwuagu, C.E.1
Yu, C.R.2
Zhang, M.3
Mahdi, R.M.4
Kim, S.J.5
Gery, I.6
-
11
-
-
0032567353
-
The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities
-
Song MM, Shuai K. The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities. J Biol Chem 1998 273 : 35056 62.
-
(1998)
J Biol Chem
, vol.273
, pp. 35056-62
-
-
Song, M.M.1
Shuai, K.2
-
12
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
Starr R, Willson TA, Viney EM et al. A family of cytokine-inducible inhibitors of signalling. Nature 1997 387 : 917 21.
-
(1997)
Nature
, vol.387
, pp. 917-21
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
-
13
-
-
0038807434
-
Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1
-
Eyles JL, Metcalf D, Grusby MJ, Hilton DJ, Starr R. Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1. J Biol Chem 2002 277 : 43735 40.
-
(2002)
J Biol Chem
, vol.277
, pp. 43735-40
-
-
Eyles, J.L.1
Metcalf, D.2
Grusby, M.J.3
Hilton, D.J.4
Starr, R.5
-
14
-
-
0036644335
-
Impaired IFN-gamma-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1
-
Federici M, Giustizieri ML, Scarponi C, Girolomoni G, Albanesi C. Impaired IFN-gamma-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1. J Immunol 2002 169 : 434 42.
-
(2002)
J Immunol
, vol.169
, pp. 434-42
-
-
Federici, M.1
Giustizieri, M.L.2
Scarponi, C.3
Girolomoni, G.4
Albanesi, C.5
-
15
-
-
0042967672
-
SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses
-
Seki Y, Inoue H, Nagata N et al. SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses. Nat Med 2003 9 : 1047 54.
-
(2003)
Nat Med
, vol.9
, pp. 1047-54
-
-
Seki, Y.1
Inoue, H.2
Nagata, N.3
-
16
-
-
0036790814
-
Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation
-
Seki Y, Hayashi K, Matsumoto A et al. Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. Proc Natl Acad Sci USA 2002 99 : 13003 8.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13003-8
-
-
Seki, Y.1
Hayashi, K.2
Matsumoto, A.3
-
17
-
-
2942735129
-
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function
-
Brender C, Columbus R, Metcalf D et al. SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function. Mol Cell Biol 2004 24 : 6094 103.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6094-103
-
-
Brender, C.1
Columbus, R.2
Metcalf, D.3
-
18
-
-
0042531736
-
Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells
-
Yu CR, Mahdi RM, Ebong S, Vistica BP, Gery I, Egwuagu CE. Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells. J Biol Chem 2003 278 : 29752 9.
-
(2003)
J Biol Chem
, vol.278
, pp. 29752-9
-
-
Yu, C.R.1
Mahdi, R.M.2
Ebong, S.3
Vistica, B.P.4
Gery, I.5
Egwuagu, C.E.6
-
19
-
-
0032772125
-
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice
-
Matsumoto A, Seki Y, Kubo M et al. Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice. Mol Cell Biol 1999 19 : 6396 407.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6396-407
-
-
Matsumoto, A.1
Seki, Y.2
Kubo, M.3
-
20
-
-
33645849231
-
Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1
-
Kinjyo I, Inoue H, Hamano S et al. Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1. J Exp Med 2006 203 : 1021 31.
-
(2006)
J Exp Med
, vol.203
, pp. 1021-31
-
-
Kinjyo, I.1
Inoue, H.2
Hamano, S.3
-
21
-
-
34848898431
-
Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells
-
Matsumura Y, Kobayashi T, Ichiyama K et al. Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells. J Immunol 2007 179 : 2170 9.
-
(2007)
J Immunol
, vol.179
, pp. 2170-9
-
-
Matsumura, Y.1
Kobayashi, T.2
Ichiyama, K.3
-
22
-
-
34447568535
-
Regulatory transplantation tolerance and "stemness": Evidence that Foxp3 may play a regulatory role in SOCS-3 gene transcription
-
Muthukumarana P, Chae WJ, Maher S, Rosengard BR, Bothwell AL, Metcalfe SM. Regulatory transplantation tolerance and "stemness": evidence that Foxp3 may play a regulatory role in SOCS-3 gene transcription. Transplantation 2007 84 (Suppl.) : S6 11.
-
(2007)
Transplantation
, vol.84
-
-
Muthukumarana, P.1
Chae, W.J.2
Maher, S.3
Rosengard, B.R.4
Bothwell, A.L.5
Metcalfe, S.M.6
-
23
-
-
34547901394
-
Deficient SOCS3 expression in CD4+CD25+FoxP3+ regulatory T cells and SOCS3-mediated suppression of Treg function
-
Pillemer BB, Xu H, Oriss TB, Qi Z, Ray A. Deficient SOCS3 expression in CD4+CD25+FoxP3+ regulatory T cells and SOCS3-mediated suppression of Treg function. Eur J Immunol 2007 37 : 2082 9.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2082-9
-
-
Pillemer, B.B.1
Xu, H.2
Oriss, T.B.3
Qi, Z.4
Ray, A.5
-
24
-
-
10744227089
-
Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases
-
Fujimoto M, Tsutsui H, Xinshou O et al. Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases. Int Immunol 2004 16 : 303 14.
-
(2004)
Int Immunol
, vol.16
, pp. 303-14
-
-
Fujimoto, M.1
Tsutsui, H.2
Xinshou, O.3
-
25
-
-
0036144888
-
Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo
-
Gavin MA, Clarke SR, Negrou E, Gallegos A, Rudensky A. Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo. Nat Immunol 2002 3 : 33 41.
-
(2002)
Nat Immunol
, vol.3
, pp. 33-41
-
-
Gavin, M.A.1
Clarke, S.R.2
Negrou, E.3
Gallegos, A.4
Rudensky, A.5
-
26
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh RS, Whitters MJ, Piccirillo CA et al. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 2002 16 : 311 23.
-
(2002)
Immunity
, vol.16
, pp. 311-23
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
-
27
-
-
33646890858
-
Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis
-
Ekelund E, Saaf A, Tengvall-Linder M et al. Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis. Am J Hum Genet 2006 78 : 1060 5.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 1060-5
-
-
Ekelund, E.1
Saaf, A.2
Tengvall-Linder, M.3
-
28
-
-
34247265510
-
Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma
-
Harada M, Nakashima K, Hirota T et al. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am J Respir Cell Mol Biol 2007 36 : 491 6.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 491-6
-
-
Harada, M.1
Nakashima, K.2
Hirota, T.3
-
29
-
-
13244260282
-
Influence of lifestyle and behaviour on the development of the immune system and allergic diseases. the LISA birth cohort study
-
In: Merker, N., Göpfert, P., Kirch, W., eds. Regensburg: S. Roderer Verlag
-
Borte M, Schulz R, Lehmann I et al. Influence of lifestyle and behaviour on the development of the immune system and allergic diseases. The LISA birth cohort study. In : Merker N, Göpfert P, Kirch W, eds. Public health research and practise. Regensburg : S. Roderer Verlag, 2001 59 77.
-
(2001)
Public Health Research and Practise.
, pp. 59-77
-
-
Borte, M.1
Schulz, R.2
Lehmann, I.3
-
30
-
-
33750573924
-
Association of neuropeptides with Th1/Th2 balance and allergic sensitization in children
-
Herberth G, Daegelmann C, Weber A et al. Association of neuropeptides with Th1/Th2 balance and allergic sensitization in children. Clin Exp Allergy 2006 36 : 1408 16.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 1408-16
-
-
Herberth, G.1
Daegelmann, C.2
Weber, A.3
-
31
-
-
0036954079
-
Studying school beginners in western and eastern Germany: Allergy trends and sensitisations 1991-2000
-
Kramer U, Link E, Oppermann H et al. Studying school beginners in western and eastern Germany: allergy trends and sensitisations 1991-2000. Gesundheitswesen 2002 64 : 657 63.
-
(2002)
Gesundheitswesen
, vol.64
, pp. 657-63
-
-
Kramer, U.1
Link, E.2
Oppermann, H.3
-
32
-
-
0002441286
-
Elevated levels of total serum IgE in East German children: Atopy, parasites, or pollutants?
-
Behrendt H, Krämer U, Dolgner R et al. Elevated levels of total serum IgE in East German children: atopy, parasites, or pollutants? Allergo J 1993 2 : 31 40.
-
(1993)
Allergo J
, vol.2
, pp. 31-40
-
-
Behrendt, H.1
Krämer, U.2
Dolgner, R.3
-
33
-
-
0036110330
-
T cell reactivity in neonates from an East and a West German city- results of the LISA study
-
Lehmann I, Thoelke A, Weiss M et al. T cell reactivity in neonates from an East and a West German city- results of the LISA study. Allergy 2002 57 : 129 36.
-
(2002)
Allergy
, vol.57
, pp. 129-36
-
-
Lehmann, I.1
Thoelke, A.2
Weiss, M.3
-
34
-
-
3242657297
-
SOCS: Role in inflammation, allergy and homeostasis
-
Elliott J, Johnston JA. SOCS: role in inflammation, allergy and homeostasis. Trends Immunol 2004 25 : 434 40.
-
(2004)
Trends Immunol
, vol.25
, pp. 434-40
-
-
Elliott, J.1
Johnston, J.A.2
-
35
-
-
10344262891
-
SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells
-
Hebenstreit D, Luft P, Schmiedlechner A, Duschl A, Horejs-Hoeck J. SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells. Mol Immunol 2005 42 : 295 303.
-
(2005)
Mol Immunol
, vol.42
, pp. 295-303
-
-
Hebenstreit, D.1
Luft, P.2
Schmiedlechner, A.3
Duschl, A.4
Horejs-Hoeck, J.5
-
36
-
-
33846523494
-
Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling
-
Dickensheets H, Vazquez N, Sheikh F et al. Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling. Genes Immun 2007 8 : 21 7.
-
(2007)
Genes Immun
, vol.8
, pp. 21-7
-
-
Dickensheets, H.1
Vazquez, N.2
Sheikh, F.3
-
37
-
-
33746190828
-
Dendritic cells transduced with SOCS-3 exhibit a tolerogenic/DC2 phenotype that directs type 2 Th cell differentiation in vitro and in vivo
-
Li Y, Chu N, Rostami A, Zhang GX. Dendritic cells transduced with SOCS-3 exhibit a tolerogenic/DC2 phenotype that directs type 2 Th cell differentiation in vitro and in vivo. J Immunol 2006 177 : 1679 88.
-
(2006)
J Immunol
, vol.177
, pp. 1679-88
-
-
Li, Y.1
Chu, N.2
Rostami, A.3
Zhang, G.X.4
-
38
-
-
13944258449
-
SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): A potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy
-
Egwuagu CE, Yu CR, Li Z, Nussenblatt RB. SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy. J Autoimmun 2005 24 : 39 46.
-
(2005)
J Autoimmun
, vol.24
, pp. 39-46
-
-
Egwuagu, C.E.1
Yu, C.R.2
Li, Z.3
Nussenblatt, R.B.4
-
39
-
-
0142134448
-
T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: Predominant role of GATA-3
-
Chakir H, Wang H, Lefebvre DE, Webb J, Scott FW. T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3. J Immunol Methods 2003 278 : 157 69.
-
(2003)
J Immunol Methods
, vol.278
, pp. 157-69
-
-
Chakir, H.1
Wang, H.2
Lefebvre, D.E.3
Webb, J.4
Scott, F.W.5
-
40
-
-
0346969978
-
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+
-
Walker MR, Kasprowicz DJ, Gersuk VH et al. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+. J Clin Invest 2003 112 : 1437 43.
-
(2003)
J Clin Invest
, vol.112
, pp. 1437-43
-
-
Walker, M.R.1
Kasprowicz, D.J.2
Gersuk, V.H.3
|