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Volumn 115, Issue 12, 2005, Pages 3573-3578

Absence of ghrelin protects against early-onset obesity

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; GROWTH HORMONE SECRETAGOGUE RECEPTOR;

EID: 31044452189     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI26003     Document Type: Article
Times cited : (329)

References (31)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., et al. 1999. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1
  • 2
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschöp, M., Smiley, D.L., and Heiman, M.L. 2002. Ghrelin induces adiposity in rodents. Nature. 407:908-913.
    • (2002) Nature , vol.407 , pp. 908-913
    • Tschöp, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 3
    • 0035843183 scopus 로고    scopus 로고
    • A role for ghrelin in the central regulation of feeding
    • Nakazato, M., et al. 2001. A role for ghrelin in the central regulation of feeding. Nature. 409:194-198.
    • (2001) Nature , vol.409 , pp. 194-198
    • Nakazato, M.1
  • 4
    • 2642564305 scopus 로고    scopus 로고
    • Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach
    • Moesgaard, S.G., et al. 2004. Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach. Regul. Pept. 120:261-267.
    • (2004) Regul. Pept. , vol.120 , pp. 261-267
    • Moesgaard, S.G.1
  • 5
    • 0036141195 scopus 로고    scopus 로고
    • Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: Enteric distribution, ontogeny, influence of endocrine, and dietary manipulations
    • Lee, H.M., Wang, G., Englander, E.W., Kojima, M., Greeley, G.H., Jr. 2002. Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology. 143:185-190.
    • (2002) Endocrinology , vol.143 , pp. 185-190
    • Lee, H.M.1    Wang, G.2    Englander, E.W.3    Kojima, M.4    Greeley Jr., G.H.5
  • 6
    • 0032744366 scopus 로고    scopus 로고
    • Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat
    • Willesen, M.G., Kristensen, P., and Romer, J. 1999. Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat. Neuroendocrinology.70:306-316.
    • (1999) Neuroendocrinology , vol.70 , pp. 306-316
    • Willesen, M.G.1    Kristensen, P.2    Romer, J.3
  • 7
    • 0035709038 scopus 로고    scopus 로고
    • The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis
    • Cone, R.D., et al. 2001. The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis. Int. J. Obes. Relat. Metab. Disord. 25(Suppl. 5):S63-S67.
    • (2001) Int. J. Obes. Relat. Metab. Disord. , vol.25 , Issue.5 SUPPL.
    • Cone, R.D.1
  • 8
    • 0037456519 scopus 로고    scopus 로고
    • The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
    • Cowley, M.A., et al. 2003. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37:649-661.
    • (2003) Neuron. , vol.37 , pp. 649-661
    • Cowley, M.A.1
  • 9
    • 0037320674 scopus 로고    scopus 로고
    • Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus
    • Seoane, L.M., et al. 2003. Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus. Endocrinology. 144:544-551.
    • (2003) Endocrinology , vol.144 , pp. 544-551
    • Seoane, L.M.1
  • 10
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun, Y., Ahmed, S., and Smith, R.G. 2003. Deletion of ghrelin impairs neither growth nor appetite. Mol. Cell. Biol. 23:7973-7981.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 11
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun, Y., Wang, P., Zheng, H., and Smith, R.G. 2004. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc. Natl. Acad. Sci. U. S. A. 101:4679-4684.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 12
    • 2542597708 scopus 로고    scopus 로고
    • Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference
    • Wortley, K.E., et al. 2004. Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference. Proc. Natl. Acad. Sci. U. S. A. 101:8227-8232.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 8227-8232
    • Wortley, K.E.1
  • 13
    • 31044451759 scopus 로고    scopus 로고
    • Mice lacking ghrelin receptors resist the development of diet-induced obesity
    • doi:10.1172/JCI26002
    • Zigman, J.M., et al. 2005. Mice lacking ghrelin receptors resist the development of diet-induced obesity. J. Clin. Invest. 115:3564-3572. doi:10.1172/JCI26002.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3564-3572
    • Zigman, J.M.1
  • 14
    • 4644274876 scopus 로고    scopus 로고
    • Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats
    • Tang-Christensen, M., et al. 2004. Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology. 145:4645-4652.
    • (2004) Endocrinology , vol.145 , pp. 4645-4652
    • Tang-Christensen, M.1
  • 15
    • 21644486848 scopus 로고    scopus 로고
    • Impact of growth hormone status on body composition and the skeleton
    • Mukherjee, A., Murray, R.D., and Shalet, S.M. 2004. Impact of growth hormone status on body composition and the skeleton. Horm. Res. 62(Suppl. 3):35-41.
    • (2004) Horm. Res. , vol.62 , Issue.3 SUPPL. , pp. 35-41
    • Mukherjee, A.1    Murray, R.D.2    Shalet, S.M.3
  • 17
    • 0025973802 scopus 로고
    • Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man
    • Veldhuis, J.D., et al. 1991. Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J. Clin. Endocrinol. Metab. 72:51-59.
    • (1991) J. Clin. Endocrinol. Metab. , vol.72 , pp. 51-59
    • Veldhuis, J.D.1
  • 18
    • 0029923352 scopus 로고    scopus 로고
    • The obese growth hormone (GH)-deficient dwarf rat: Body fat responses to patterned delivery of GH and insulin-like growth factor-I
    • Clark, R.G., et al. 1996. The obese growth hormone (GH)-deficient dwarf rat: body fat responses to patterned delivery of GH and insulin-like growth factor-I. Endocrinology. 137:1904-1912.
    • (1996) Endocrinology , vol.137 , pp. 1904-1912
    • Clark, R.G.1
  • 19
    • 1642464956 scopus 로고    scopus 로고
    • Physiological studies of transgenic mice overexpressing growth hormone (GH) secretagogue receptor 1A in GH-releasing hormone neurons
    • Lall, S., et al. 2004. Physiological studies of transgenic mice overexpressing growth hormone (GH) secretagogue receptor 1A in GH-releasing hormone neurons. Endocrinology. 145:1602-1611.
    • (2004) Endocrinology , vol.145 , pp. 1602-1611
    • Lall, S.1
  • 20
    • 12344326642 scopus 로고    scopus 로고
    • Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet
    • Olsson, B., et al. 2005. Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet. Endocrinology. 146:920-930.
    • (2005) Endocrinology , vol.146 , pp. 920-930
    • Olsson, B.1
  • 21
    • 0037474044 scopus 로고    scopus 로고
    • Postnatal development of the hypothalamic neuropeptide Y system
    • Grove, K.L., Allen, S., Grayson, B.E., and Smith, M.S. 2003. Postnatal development of the hypothalamic neuropeptide Y system. Neuroscience. 116:393-406.
    • (2003) Neuroscience , vol.116 , pp. 393-406
    • Grove, K.L.1    Allen, S.2    Grayson, B.E.3    Smith, M.S.4
  • 22
    • 0038043228 scopus 로고    scopus 로고
    • Ontogeny of the hypothalamic neuropeptide Y system
    • Grove, K.L, and Smith, M.S. 2003. Ontogeny of the hypothalamic neuropeptide Y system. Physiol. Behav. 79:47-63.
    • (2003) Physiol. Behav. , vol.79 , pp. 47-63
    • Grove, K.L.1    Smith, M.S.2
  • 23
    • 2542475178 scopus 로고    scopus 로고
    • Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein
    • Chen, H.Y., et al. 2004. Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology. 145:2607-2612.
    • (2004) Endocrinology , vol.145 , pp. 2607-2612
    • Chen, H.Y.1
  • 24
    • 1842529267 scopus 로고    scopus 로고
    • Rapid rewiring of arcuate nucleus feeding circuits by leptin
    • Pinto, S., et al. 2004. Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science. 304:110-115.
    • (2004) Science , vol.304 , pp. 110-115
    • Pinto, S.1
  • 25
    • 1242351742 scopus 로고    scopus 로고
    • Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet
    • Ozanne, S.E., Lewis, R., Jennings, B.J., and Hales, C.N. 2004. Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet. Clin. Sci. (Lond.). 106:141-145.
    • (2004) Clin. Sci. (Lond.) , vol.106 , pp. 141-145
    • Ozanne, S.E.1    Lewis, R.2    Jennings, B.J.3    Hales, C.N.4
  • 26
    • 19444364290 scopus 로고    scopus 로고
    • Early dietary intervention: Long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers
    • Velkoska, E., Cole, T.J., and Morris, M.J. 2005. Early dietary intervention: long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers. Am. J. Physiol. Endocrinol. Metab. 288:E1236-E1243.
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.288
    • Velkoska, E.1    Cole, T.J.2    Morris, M.J.3
  • 27
    • 0842328994 scopus 로고    scopus 로고
    • Lifespan: Catch-up growth and obesity in male mice
    • Ozanne, S.E., and Hales, C.N. 2004. Lifespan: catch-up growth and obesity in male mice. Nature. 427:411-412.
    • (2004) Nature , vol.427 , pp. 411-412
    • Ozanne, S.E.1    Hales, C.N.2
  • 28
    • 0038023191 scopus 로고    scopus 로고
    • High-throughput engineering of the mouse genome coupled with high-resolution expression analysis
    • Valenzuela, D.M., et al. 2003. High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat. Biotechnol. 21:652-659.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 652-659
    • Valenzuela, D.M.1
  • 29
    • 0345060844 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice
    • Sleeman, M.W., et al. 2003. Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice. Proc. Natl. Acad. Sci. U. S. A. 100:14297-14302.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 14297-14302
    • Sleeman, M.W.1
  • 30
    • 1642423858 scopus 로고    scopus 로고
    • Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist
    • Iida, K., et al. 2004. Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist. Endocrinology. 145:1564-1570.
    • (2004) Endocrinology , vol.145 , pp. 1564-1570
    • Iida, K.1
  • 31
    • 26044482961 scopus 로고    scopus 로고
    • Genetic differences in the insulin-like growth factor-I (IGF-I) gene among inbred strains of mice with different serum IGF-I levels
    • Iida, K., Rosen, C.J., Ackert-Bicknell, C., and Thorner, M.O. 2005. Genetic differences in the insulinlike growth factor-I (IGF-I) gene among inbred strains of mice with different serum IGF-I levels. J. Endocrinol. 186:481-489.
    • (2005) J. Endocrinol. , vol.186 , pp. 481-489
    • Iida, K.1    Rosen, C.J.2    Ackert-Bicknell, C.3    Thorner, M.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.