Alpha anomer of 5-aza-2′-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells

Biochemical Pharmacology

Volumn 75, Issue 4, 2008, Pages 965-972

  Hájek, Miroslav ^a   Votruba, Ivan ^a   Holý, Antonín ^a   Krečmerová, Marcela ^a   Tloušt'ová, Eva ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Alpha 5 aza 2 deoxycytidine; c myc; DNA hypomethylation; hTERT

Indexed keywords

1 [3 HYDROXY 2 (PHOSPHONOMETHOXY)PROPYL] 5 AZACYTOSINE; 3 (9 ADENINYL) 2 HYDROXYPROPIONIC ACID; 5 AZA 2' DEOXYCYTIDINE; 5 FLUOROZEBULARINE; 9 (2,3 DIHYDROXYPROPYL)ADENINE; DNA; MESSENGER RNA; NUCLEOSIDE ANALOG; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; PRIORITY JOURNAL;

ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; DNA; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HL-60 CELLS; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; STEREOISOMERISM; TELOMERASE;

EID: 38749144011     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.10.018     Document Type: Article

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