Synthesis and biological activity of novel peptide mimetics as melanocortin receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 1223-1228

  Liu, Xue Wei ^a   Ma, Jimei ^a   Colson, Anny Odile ^b   Doersen, Doreen Cross ^b   Ebetino, Frank H ^b  

^a Nanyang Technological University   (Singapore)

^b PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

Author keywords

Homology model; MC4R agonist; Melanocortin receptor; Peptidomimetics

Indexed keywords

ARGININE; GUANIDINE; HORMONE RECEPTOR STIMULATING AGENT; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOLOGICAL ACTIVITY; DRUG SYNTHESIS; HYDROGEN BOND; PHARMACOPHORE;

ARGININE; GUANIDINES; HUMANS; MODELS, BIOLOGICAL; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; PEPTIDES; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTOR, MELANOCORTIN, TYPE 4; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 38749125133     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.109     Document Type: Article

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