Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 21, 2005, Pages 4819-4823

  Hocke, Carsten ^a   Prante, Olaf ^a   Löber, Stefan ^b   Hübner, Harald ^b   Gmeiner, Peter ^b   Kuwert, Torsten ^a  

^a Department of Nuclear Medicine ^*  (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

D3 receptor; Dopamine; PET; Radioligand

Indexed keywords

AMIDE; DOPAMINE 3 RECEPTOR; FLUORINE 18; PHENYLPIPERAZINE; PIPERAZINE DERIVATIVE; RADIOLIGAND; UNCLASSIFIED DRUG; CONTRAST MEDIUM; DIAGNOSTIC AGENT; FLUORINE; LIGAND; RADIOPHARMACEUTICAL AGENT;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; IMAGING; IN VITRO STUDY; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RAT; RECEPTOR AFFINITY; ANIMAL; METHODOLOGY; RADIOASSAY; STRUCTURE ACTIVITY RELATION; SWINE; SYNTHESIS;

ANIMALS; CONTRAST MEDIA; FLUORINE RADIOISOTOPES; LIGANDS; POSITRON-EMISSION TOMOGRAPHY; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 25144504927     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.037     Document Type: Article

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