Double-mismatched siRNAs enhance selective gene silencing of a mutant ALS-causing allele

Acta Pharmacologica Sinica

Volumn 29, Issue 2, 2008, Pages 211-216

  Geng, Chang Ming ^a   Ding, Hong Liu ^b,c  

^a No 85 Hospital of PLA   (China)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Amyotrophic lateral sclerosis; Neurodegenerative disease; RNA interference; siRNA; Superoxide dismutase 1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; LUCIFERASE; SMALL INTERFERING RNA;

ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; ANTISENSE THERAPY; ARTICLE; BASE MISPAIRING; EMBRYO; GENE FUNCTION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL;

ALLELES; AMYOTROPHIC LATERAL SCLEROSIS; BASE PAIR MISMATCH; CELL LINE; GENE SILENCING; HUMANS; MUTATION; OLIGONUCLEOTIDES, ANTISENSE; RNA, SMALL INTERFERING; SUPEROXIDE DISMUTASE;

EID: 38749087657     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00740.x     Document Type: Article

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