Dephosphorylation of β2-syntrophin and Ca2+/μ-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion

EMBO Journal

Volumn 20, Issue 15, 2001, Pages 4013-4023

  Ort, Tatiana ^a   Voronov, Sergei ^a   Guo, Jun ^a   Zawalich, Kathleen ^b   Froehner, Stanley C ^c   Zawalich, Walter ^b   Solimena, Michele ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF NURSING   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Actin; Diabetes; IA 2; Secretory granule; Tyrosine phosphatase

Indexed keywords

ACTIN; CALPAIN; CELL ANTIGEN; OKADAIC ACID; PROTEIN ICA512; SYNTROPHIN; UNCLASSIFIED DRUG; UTROPHIN; AUTOANTIGEN; CALPEPTIN; CYSTEINE PROTEINASE INHIBITOR; CYTOSKELETON PROTEIN; DIPEPTIDE; DYSTROPHIN ASSOCIATED PROTEIN; ENZYME INHIBITOR; IA 2 PROTEIN; IA-2 PROTEIN; INSULIN; MEMBRANE PROTEIN; PROTEIN PRECURSOR; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DEPHOSPHORYLATION; INSULIN RELEASE; MOUSE; NEUROSECRETORY CELL; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; RAT; SECRETORY GRANULE; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; ENZYME ACTIVATION; HUMAN; METABOLISM; MOLECULAR GENETICS; PANCREAS ISLET; PHOSPHORYLATION; SECRETION; SECRETORY VESICLE;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIGENS; CALPAIN; CYSTEINE PROTEINASE INHIBITORS; CYTOSKELETAL PROTEINS; DIPEPTIDES; DYSTROPHIN-ASSOCIATED PROTEINS; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INSULIN; ISLETS OF LANGERHANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; OKADAIC ACID; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PRECURSORS; PROTEIN-TYROSINE-PHOSPHATASE; RATS; SECRETORY VESICLES; TUMOR CELLS, CULTURED; UTROPHIN;

EID: 0035421958     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.15.4013     Document Type: Article

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