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Volumn 455, Issue 6, 2008, Pages 1119-1128

Locus coeruleus noradrenergic neurons and CO2 drive to breathing

Author keywords

A6; Catecholamine; Chemosensitivity; Hypercapnia; Pons; Ventilation

Indexed keywords

ASCORBIC ACID; CARBON DIOXIDE; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

EID: 38649125267     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0338-8     Document Type: Article
Times cited : (153)

References (70)
  • 1
    • 0035179712 scopus 로고    scopus 로고
    • Synchronized rhythms in chemosensitive neurons of the locus coeruleus in the absence of chemical synaptic transmission
    • 1-2
    • Andrzejewski M, Mückenhoff K, Scheid P, Ballantyne D (2001) Synchronized rhythms in chemosensitive neurons of the locus coeruleus in the absence of chemical synaptic transmission. Respir Physiol 129(1-2):123-140
    • (2001) Respir Physiol , vol.129 , pp. 123-140
    • Andrzejewski, M.1    Mückenhoff, K.2    Scheid, P.3    Ballantyne, D.4
  • 2
    • 4043063512 scopus 로고    scopus 로고
    • Thermoeffector neuronal pathways in fever: Role of the locus coeruleus
    • Almeida MC, Steiner AA, Coimbra NC, Branco LGS (2004) Thermoeffector neuronal pathways in fever: role of the locus coeruleus. J Physiol 558:283-294
    • (2004) J Physiol , vol.558 , pp. 283-294
    • Almeida, M.C.1    Steiner, A.A.2    Coimbra, N.C.3    Branco, L.G.S.4
  • 3
    • 0032551696 scopus 로고    scopus 로고
    • C-fos expression and electrolytic lesions studies reveal activation of the posterior region of locus coeruleus during hemorrhage induced hypotension
    • 2
    • Anselmo-Franci JA, Peres-Polon VL, da Rocha-Barros VM, Moreira ER, Franci CR, Rocha MJ (1998) C-fos expression and electrolytic lesions studies reveal activation of the posterior region of locus coeruleus during hemorrhage induced hypotension. Brain Res 799(2):278-284
    • (1998) Brain Res , vol.799 , pp. 278-284
    • Anselmo-Franci, J.A.1    Peres-Polon, V.L.2    Da Rocha-Barros, V.M.3    Moreira, E.R.4    Franci, C.R.5    Rocha, M.J.6
  • 4
    • 0025076980 scopus 로고
    • Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat
    • 2
    • Astier B, Van Bockstaele EJ, Aston-Jones G, Pieribone VA (1990) Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat. Neurosci Lett 118(2):141-146
    • (1990) Neurosci Lett , vol.118 , pp. 141-146
    • Astier, B.1    Van Bockstaele, E.J.2    Aston-Jones, G.3    Pieribone, V.A.4
  • 5
    • 0022981586 scopus 로고
    • The brain nucleus locus coeruleus: Restricted afferent control of a broad efferent network
    • 4777
    • Aston-Jones G, Ennis M, Pieribone VA, Nickell WT, Shipley MT (1986) The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network. Science 234(4777):734-737
    • (1986) Science , vol.234 , pp. 734-737
    • Aston-Jones, G.1    Ennis, M.2    Pieribone, V.A.3    Nickell, W.T.4    Shipley, M.T.5
  • 7
    • 0026522772 scopus 로고
    • Inhibition of noradrenergic locus coeruleus neurons by C1 adrenergic cells in the rostral ventral medulla
    • 2
    • Aston-Jones G, Astier B, Ennis M (1992) Inhibition of noradrenergic locus coeruleus neurons by C1 adrenergic cells in the rostral ventral medulla. Neuroscience 48(2):371-381
    • (1992) Neuroscience , vol.48 , pp. 371-381
    • Aston-Jones, G.1    Astier, B.2    Ennis, M.3
  • 8
    • 0001446930 scopus 로고
    • The locus coeruleus, A5 and A7 noradrenergic cell groups
    • Academic San Diego, CA
    • Aston-Jones G, Shipley MT, Grzanna R (1995) The locus coeruleus, A5 and A7 noradrenergic cell groups. In: Paxinos G (ed) The rat nervous system. Academic, San Diego, CA, pp 183-213
    • (1995) The Rat Nervous System , pp. 183-213
    • Aston-Jones, G.1    Shipley, M.T.2    Grzanna, R.3    Paxinos, G.4
  • 9
    • 0035189885 scopus 로고    scopus 로고
    • Central chemosensitivity of respiration: Brief overview
    • Ballantyne D, Scheid P (2001) Central chemosensitivity of respiration: brief overview. Respir Physiol 129:5-12
    • (2001) Respir Physiol , vol.129 , pp. 5-12
    • Ballantyne, D.1    Scheid, P.2
  • 10
    • 0031713537 scopus 로고    scopus 로고
    • Effect of nitric oxide synthase inhibition on hypercapnia-induced hypothermia and hyperventilation
    • 3
    • Barros RC, Branco LG (1998) Effect of nitric oxide synthase inhibition on hypercapnia-induced hypothermia and hyperventilation. J Appl Physiol 85(3):967-972
    • (1998) J Appl Physiol , vol.85 , pp. 967-972
    • Barros, R.C.1    Branco, L.G.2
  • 11
    • 0014867206 scopus 로고
    • Control of breathing in experimental anemia
    • Bartlett D, Tenney SM (1970) Control of breathing in experimental anemia. Respir Physiol 10:384-395
    • (1970) Respir Physiol , vol.10 , pp. 384-395
    • Bartlett, D.1    Tenney, S.M.2
  • 12
    • 0030050524 scopus 로고    scopus 로고
    • Evidence for central chemoreception in the midline raphe
    • Bernard DG, Li A, Nattie EE (1996) Evidence for central chemoreception in the midline raphe. J Appl Physiol 80:108-115
    • (1996) J Appl Physiol , vol.80 , pp. 108-115
    • Bernard, D.G.1    Li, A.2    Nattie, E.E.3
  • 13
    • 0037381980 scopus 로고    scopus 로고
    • The locus coeruleus-noradrenergic system: Modulation of behavioral state and state-dependent cognitive processes
    • 1
    • Berridge CW, Waterhouse BD (2003) The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Brain Res Rev 42(1):33-84
    • (2003) Brain Res Brain Res Rev , vol.42 , pp. 33-84
    • Berridge, C.W.1    Waterhouse, B.D.2
  • 14
    • 33750910876 scopus 로고    scopus 로고
    • Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation
    • 5
    • Card JP, Sved JC, Craig B, Raizada M, Vazquez J, Sved AF (2006) Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: implications for the central control of cardiovascular regulation. J Comp Neurol 499(5):840-859
    • (2006) J Comp Neurol , vol.499 , pp. 840-859
    • Card, J.P.1    Sved, J.C.2    Craig, B.3    Raizada, M.4    Vazquez, J.5    Sved, A.F.6
  • 15
    • 0027219628 scopus 로고
    • Widespread sites of brain stem ventilatory chemoreceptors
    • Coates EL, Li A, Nattie EE (1993) Widespread sites of brain stem ventilatory chemoreceptors. J Appl Physiol 75:5-14
    • (1993) J Appl Physiol , vol.75 , pp. 5-14
    • Coates, E.L.1    Li, A.2    Nattie, E.E.3
  • 16
    • 0035140873 scopus 로고    scopus 로고
    • Respiratory effects of stimulation of cell bodies of the A5 region in anesthetized rats
    • Dawid-Milner M, Lara J, Gonzales-Baron S, Spyer K (2001) Respiratory effects of stimulation of cell bodies of the A5 region in anesthetized rats. Pflugers Arch 441:434-443
    • (2001) Pflugers Arch , vol.441 , pp. 434-443
    • Dawid-Milner, M.1    Lara, J.2    Gonzales-Baron, S.3    Spyer, K.4
  • 17
    • 0035183266 scopus 로고    scopus 로고
    • Cell-cell coupling in CO(2)/H(+)-excited neurons in brainstem slices
    • 1-2
    • Dean JB, Kinkade EA, Putnam RW (2001) Cell-cell coupling in CO(2)/H(+)-excited neurons in brainstem slices. Respir Physiol 129(1-2):83-100
    • (2001) Respir Physiol , vol.129 , pp. 83-100
    • Dean, J.B.1    Kinkade, E.A.2    Putnam, R.W.3
  • 19
    • 0019375059 scopus 로고
    • Hypercapnia and hypoxia: Chemoreceptor-mediated control of locus coeruleus neurons and splanchnic, sympathetic nerves
    • Elam M, Yao T, Thoren P, Svensson TH (1981) Hypercapnia and hypoxia: chemoreceptor-mediated control of locus coeruleus neurons and splanchnic, sympathetic nerves. Brain Res 222:373-381
    • (1981) Brain Res , vol.222 , pp. 373-381
    • Elam, M.1    Yao, T.2    Thoren, P.3    Svensson, T.H.4
  • 20
    • 0027992053 scopus 로고
    • Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotonergic neurons of the rat brainstem
    • Erickson JT, Millhorn DE (1984) Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotonergic neurons of the rat brainstem. J Comp Neurol 348:161-182
    • (1984) J Comp Neurol , vol.348 , pp. 161-182
    • Erickson, J.T.1    Millhorn, D.E.2
  • 21
    • 0033220624 scopus 로고    scopus 로고
    • Role of nitric oxide in hypoxia-induced hyperventilation and hypothermia: Participation of the locus coeruleus
    • 11
    • Fabris G, Anselmo-Franci JA, Branco LG (1999) Role of nitric oxide in hypoxia-induced hyperventilation and hypothermia: participation of the locus coeruleus. Braz J Med Biol Res 32(11):1389-1398
    • (1999) Braz J Med Biol Res , vol.32 , pp. 1389-1398
    • Fabris, G.1    Anselmo-Franci, J.A.2    Branco, L.G.3
  • 23
    • 0036623783 scopus 로고    scopus 로고
    • Role of intracellular and extracellular pH in the chemosensitive response of rat locus coeruleus neurones
    • Filosa JA, Dean JB, Putnam RW (2002) Role of intracellular and extracellular pH in the chemosensitive response of rat locus coeruleus neurones. J Physiol 541:493-509
    • (2002) J Physiol , vol.541 , pp. 493-509
    • Filosa, J.A.1    Dean, J.B.2    Putnam, R.W.3
  • 24
    • 0037213231 scopus 로고    scopus 로고
    • Multiple targets of chemosensitive signaling in locus coeruleus neurons: Role of K+ and Ca2+ channels
    • 1
    • Filosa JA, Putnam RW (2003) Multiple targets of chemosensitive signaling in locus coeruleus neurons: role of K+ and Ca2+ channels. Am J Physiol Cell Physiol 284(1):C145-155
    • (2003) Am J Physiol Cell Physiol , vol.284 , pp. 145-155
    • Filosa, J.A.1    Putnam, R.W.2
  • 25
    • 0023222462 scopus 로고
    • Carotid chemoreceptor discharge responses to hypoxia and hypercapnia in normotensive and spontaneously hypertensive rats
    • Fukuda Y, Sato A, Trzebski A (1987) Carotid chemoreceptor discharge responses to hypoxia and hypercapnia in normotensive and spontaneously hypertensive rats. J Auton Nerv Syst 1:1-11
    • (1987) J Auton Nerv Syst , vol.1 , pp. 1-11
    • Fukuda, Y.1    Sato, A.2    Trzebski, A.3
  • 27
    • 33750017772 scopus 로고    scopus 로고
    • Circadian regulation of arousal: Role of the noradrenergic locus coeruleus system and light exposure
    • 10
    • González MM, Aston-Jones G (2006) Circadian regulation of arousal: role of the noradrenergic locus coeruleus system and light exposure. Sleep 29(10):1327-1336
    • (2006) Sleep , vol.29 , pp. 1327-1336
    • González, M.M.1    Aston-Jones, G.2
  • 28
    • 0032911907 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia
    • 1
    • Greenberg HE, Sica A, Batson D, Scharf SM (1999) Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia. J Appl Physiol 86(1):298-305
    • (1999) J Appl Physiol , vol.86 , pp. 298-305
    • Greenberg, H.E.1    Sica, A.2    Batson, D.3    Scharf, S.M.4
  • 29
    • 18844424364 scopus 로고    scopus 로고
    • Retrotrapezoid nucleus: A litmus test for the identification of central chemoreceptors
    • Guyenet PG, Stornetta RL, Bayliss DA, Mulkey DK (2005) Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors. Exp Physiol 90:247-253
    • (2005) Exp Physiol , vol.90 , pp. 247-253
    • Guyenet, P.G.1    Stornetta, R.L.2    Bayliss, D.A.3    Mulkey, D.K.4
  • 30
    • 0030201186 scopus 로고    scopus 로고
    • CO2-induced c-fos expression in the CNS catecholaminergic neurons
    • Haxhiu MA, Yung K, Erokwu B, Cherniack NS (1996) CO2-induced c-fos expression in the CNS catecholaminergic neurons. Respir Physiol 105:35-45
    • (1996) Respir Physiol , vol.105 , pp. 35-45
    • Haxhiu, M.A.1    Yung, K.2    Erokwu, B.3    Cherniack, N.S.4
  • 31
    • 4344655935 scopus 로고    scopus 로고
    • Medial vestibular nucleus mediates the cardiorespiratory responses to fastigial nuclear activation and hypercapnia
    • 3
    • Hernandez JP, Xu F, Frazier DT (2004) Medial vestibular nucleus mediates the cardiorespiratory responses to fastigial nuclear activation and hypercapnia. J Appl Physiol 97(3):835-842
    • (2004) J Appl Physiol , vol.97 , pp. 835-842
    • Hernandez, J.P.1    Xu, F.2    Frazier, D.T.3
  • 33
    • 0019413997 scopus 로고
    • Ventilation during prolonged hypercapnia in the rat
    • 1
    • Lai YL, Lamm JE, Hildebrandt J (1981) Ventilation during prolonged hypercapnia in the rat. J Appl Physiol 51(1):78-83
    • (1981) J Appl Physiol , vol.51 , pp. 78-83
    • Lai, Y.L.1    Lamm, J.E.2    Hildebrandt, J.3
  • 34
    • 33644849342 scopus 로고    scopus 로고
    • Catecholamine neurons in rats modulate sleep, breathing, central chemoreception, and breathing variability
    • Li A, Nattie EE (2006) Catecholamine neurons in rats modulate sleep, breathing, central chemoreception, and breathing variability. J Physiol 570:385-396
    • (2006) J Physiol , vol.570 , pp. 385-396
    • Li, A.1    Nattie, E.E.2
  • 35
    • 34347144223 scopus 로고
    • Effect of hydrogen ion concentration and carbon dioxide pressure in the cerebrospinal fluid on respiration
    • 6
    • Loeschcke HH, Koepchen HP, Gertz KH (1958) Effect of hydrogen ion concentration and carbon dioxide pressure in the cerebrospinal fluid on respiration. Pflugers Arch 266(6):569-585
    • (1958) Pflugers Arch , vol.266 , pp. 569-585
    • Loeschcke, H.H.1    Koepchen, H.P.2    Gertz, K.H.3
  • 37
    • 0015538175 scopus 로고
    • Ventilation measured by body plethysmography in hibernating mammals and in poikilotherms
    • 1
    • Malan A (1973) Ventilation measured by body plethysmography in hibernating mammals and in poikilotherms. Respir Physiol 17(1):32-44
    • (1973) Respir Physiol , vol.17 , pp. 32-44
    • Malan, A.1
  • 38
    • 0017259932 scopus 로고
    • Projections of the locus coeruleus and adjacent pontine tegmentum in the cat
    • 3
    • McBride RL, Sutin J (1976) Projections of the locus coeruleus and adjacent pontine tegmentum in the cat. J Comp Neurol 165(3):265-284
    • (1976) J Comp Neurol , vol.165 , pp. 265-284
    • McBride, R.L.1    Sutin, J.2
  • 39
    • 0026349213 scopus 로고
    • Chemical stimulation of the locus coeruleus: Inhibitory effects on hemodynamics and renal sympathetic nerve activity
    • 1-2
    • Miyawaki T, Kawamura H, Komatsu K, Yasugi T (1991) Chemical stimulation of the locus coeruleus: inhibitory effects on hemodynamics and renal sympathetic nerve activity. Brain Res 568(1-2):101-108
    • (1991) Brain Res , vol.568 , pp. 101-108
    • Miyawaki, T.1    Kawamura, H.2    Komatsu, K.3    Yasugi, T.4
  • 40
    • 0027519227 scopus 로고
    • Differential regional hemodynamic changes produced by L-glutamate stimulation of the locus coeruleus
    • 1
    • Miyawaki T, Kawamura H, Hara K, Suzuki K, Usui W, Yasugi T (1993) Differential regional hemodynamic changes produced by L-glutamate stimulation of the locus coeruleus. Brain Res 600(1):56-62
    • (1993) Brain Res , vol.600 , pp. 56-62
    • Miyawaki, T.1    Kawamura, H.2    Hara, K.3    Suzuki, K.4    Usui, W.5    Yasugi, T.6
  • 41
    • 0027232091 scopus 로고
    • Chemical stimulation of the nucleus locus coeruleus: Cardiovascular responses and baroreflex modification
    • Murase S, Takayama M, Nosaka S (1993) Chemical stimulation of the nucleus locus coeruleus: cardiovascular responses and baroreflex modification. Neurosci Lett 153:1-4
    • (1993) Neurosci Lett , vol.153 , pp. 1-4
    • Murase, S.1    Takayama, M.2    Nosaka, S.3
  • 43
    • 0033929694 scopus 로고    scopus 로고
    • Muscimol dialysis in the retrotrapezoid nucleus region inhibits breathing in the awake rat
    • 1
    • Nattie E, Li A (2000) Muscimol dialysis in the retrotrapezoid nucleus region inhibits breathing in the awake rat. J Appl Physiol 89(1):153-162
    • (2000) J Appl Physiol , vol.89 , pp. 153-162
    • Nattie, E.1    Li, A.2
  • 44
    • 0035185242 scopus 로고    scopus 로고
    • Central chemosensitivity, sleep, and wakefulness
    • Nattie EE (2001) Central chemosensitivity, sleep, and wakefulness. Respir Physiol 129:257-268
    • (2001) Respir Physiol , vol.129 , pp. 257-268
    • Nattie, E.E.1
  • 45
    • 33845422003 scopus 로고    scopus 로고
    • Neurokinin-1 receptor-expressing neurons in the ventral medulla are essential for normal central and peripheral chemoreception in the conscious rat
    • 6
    • Nattie E, Li A (2006) Neurokinin-1 receptor-expressing neurons in the ventral medulla are essential for normal central and peripheral chemoreception in the conscious rat. J Appl Physiol 101(6):1596-1606
    • (2006) J Appl Physiol , vol.101 , pp. 1596-1606
    • Nattie, E.1    Li, A.2
  • 46
    • 12344264797 scopus 로고    scopus 로고
    • Autonomic cardiovascular responses to hypercapnia in conscious rats: The roles of the chemo- and baroreceptors
    • 2
    • Oikawa S, Hirakawa H, Kusakabe T, Nakashima Y, Hayashida Y (2005) Autonomic cardiovascular responses to hypercapnia in conscious rats: the roles of the chemo- and baroreceptors. Auton Neurosci 117(2):105-114
    • (2005) Auton Neurosci , vol.117 , pp. 105-114
    • Oikawa, S.1    Hirakawa, H.2    Kusakabe, T.3    Nakashima, Y.4    Hayashida, Y.5
  • 47
    • 0032403225 scopus 로고    scopus 로고
    • Respiration-modulated membrane potential and chemosensitivity of locus coeruleus neurones in the in vitro brainstem-spinal cord of the neonatal rat
    • Oyamada Y, Ballantyne D, Muckenhoff K, Scheid P (1998) Respiration-modulated membrane potential and chemosensitivity of locus coeruleus neurones in the in vitro brainstem-spinal cord of the neonatal rat. J Physiol 513:381-398
    • (1998) J Physiol , vol.513 , pp. 381-398
    • Oyamada, Y.1    Ballantyne, D.2    Muckenhoff, K.3    Scheid, P.4
  • 48
    • 0032730182 scopus 로고    scopus 로고
    • Locus coeruleus neurones in vitro: PH-sensitive oscillations of membrane potential in an electrically coupled network.
    • 2-3
    • Oyamada Y, Andrzejewski M, Muckenhoff K, Scheid P, Ballantyne D (1999) Locus coeruleus neurones in vitro: pH-sensitive oscillations of membrane potential in an electrically coupled network. Respir Physiol 118(2-3):131-147
    • (1999) Respir Physiol , vol.118 , pp. 131-147
    • Oyamada, Y.1    Andrzejewski, M.2    Muckenhoff, K.3    Scheid, P.4    Ballantyne, D.5
  • 50
    • 0031550622 scopus 로고    scopus 로고
    • Carbon dioxide regulates the tonic activity of locus ceruleus neurons by modulating a proton- and polyamine-sensitive inward rectifier potassium current
    • Pineda J, Aghajanian GK (1997) Carbon dioxide regulates the tonic activity of locus ceruleus neurons by modulating a proton- and polyamine-sensitive inward rectifier potassium current. Neuroscience 77:723-743
    • (1997) Neuroscience , vol.77 , pp. 723-743
    • Pineda, J.1    Aghajanian, G.K.2
  • 51
    • 8644248306 scopus 로고    scopus 로고
    • Cellular mechanisms involved in CO(2) and acid signaling in chemosensitive neurons
    • 6
    • Putnam RW, Filosa JA, Ritucci NA (2004) Cellular mechanisms involved in CO(2) and acid signaling in chemosensitive neurons. Am J Physiol Cell Physiol 287(6):C1493-526
    • (2004) Am J Physiol Cell Physiol , vol.287 , pp. 1493-526
    • Putnam, R.W.1    Filosa, J.A.2    Ritucci, N.A.3
  • 52
    • 0025910897 scopus 로고
    • Adrenergic innervation of the rat nucleus locus coeruleus arises predominantly from the C1 adrenergic cell group in the rostral medulla
    • 2-3
    • Pieribone VA, Aston-Jones G (1991) Adrenergic innervation of the rat nucleus locus coeruleus arises predominantly from the C1 adrenergic cell group in the rostral medulla. Neuroscience 41(2-3):525-542
    • (1991) Neuroscience , vol.41 , pp. 525-542
    • Pieribone, V.A.1    Aston-Jones, G.2
  • 53
    • 33845786950 scopus 로고    scopus 로고
    • Role of the locus coeruleus carbon monoxide pathway in endotoxin fever in rats
    • 4
    • Ravanelli MI, Almeida MC, Branco LG (2007) Role of the locus coeruleus carbon monoxide pathway in endotoxin fever in rats. Pflugers Arch 453(4):471-476
    • (2007) Pflugers Arch , vol.453 , pp. 471-476
    • Ravanelli, M.I.1    Almeida, M.C.2    Branco, L.G.3
  • 54
    • 2642547405 scopus 로고    scopus 로고
    • Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis
    • 6
    • Richerson, GB (2004) Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 5(6):449-461
    • (2004) Nat Rev Neurosci , vol.5 , pp. 449-461
    • Richerson1    Richerson, G.B.2
  • 55
    • 0024993281 scopus 로고
    • Effects of hypercapnia and hypoxia on the cardiovascular system: Vascular capacitance and aortic chemoreceptors
    • 3
    • Rothe CF, Maass-Moreno R, Flanagan AD (1990) Effects of hypercapnia and hypoxia on the cardiovascular system: vascular capacitance and aortic chemoreceptors. Am J Physiol 259(3):H932-H939
    • (1990) Am J Physiol , vol.259
    • Rothe, C.F.1    Maass-Moreno, R.2    Flanagan, A.D.3
  • 56
    • 0029670740 scopus 로고    scopus 로고
    • Effect of CO2 on the metabolic and ventilatory responses to ambient temperature in conscious adult and newborn rats
    • Saiki C, Mortola JP (1996) Effect of CO2 on the metabolic and ventilatory responses to ambient temperature in conscious adult and newborn rats. J Physiol 491:261-269
    • (1996) J Physiol , vol.491 , pp. 261-269
    • Saiki, C.1    Mortola, J.P.2
  • 58
    • 0033625367 scopus 로고    scopus 로고
    • Pre-Botzinger complex functions as a central hypoxia chemosensor for respiration in vivo
    • Solomon IC, Edelman NH, Neubauer JA (2000) Pre-Botzinger complex functions as a central hypoxia chemosensor for respiration in vivo. J Neurophysiol 83:2854-2868
    • (2000) J Neurophysiol , vol.83 , pp. 2854-2868
    • Solomon, I.C.1    Edelman, N.H.2    Neubauer, J.A.3
  • 59
    • 0034894597 scopus 로고    scopus 로고
    • Development of in vivo ventilatory and single chemosensitive neuron responses to hypercapnia in rats
    • 2-3
    • Stunden CE, Filosa JA, Garcia AJ, Dean JB, Putnam RW (2001) Development of in vivo ventilatory and single chemosensitive neuron responses to hypercapnia in rats. Respir Physiol 127(2-3):135-155
    • (2001) Respir Physiol , vol.127 , pp. 135-155
    • Stunden, C.E.1    Filosa, J.A.2    Garcia, A.J.3    Dean, J.B.4    Putnam, R.W.5
  • 60
    • 0345309054 scopus 로고
    • Carbon dioxide and temperature regulation of homeothermic mammals
    • Springer New York
    • Stupfel M (1974) Carbon dioxide and temperature regulation of homeothermic mammals. In: Nahas G, Schaefer KE (eds) Carbon dioxide and metabolic regulations. Springer, New York, pp 163-186
    • (1974) Carbon Dioxide and Metabolic Regulations , pp. 163-186
    • Stupfel, M.1    Nahas, G.2    Schaefer, K.E.3
  • 61
    • 0023277434 scopus 로고
    • Stimulation of the locus coeruleus decreases arterial pressure
    • 1
    • Sved AF, Felsten G (1987) Stimulation of the locus coeruleus decreases arterial pressure. Brain Res 414(1):19-32
    • (1987) Brain Res , vol.414 , pp. 19-32
    • Sved, A.F.1    Felsten, G.2
  • 62
    • 22744440628 scopus 로고    scopus 로고
    • Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats
    • Pt 2
    • Taylor NC, Li A, Nattie EE (2005) Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats. J Physiol 566(Pt 2):543-557
    • (2005) J Physiol , vol.566 , pp. 543-557
    • Taylor, N.C.1    Li, A.2    Nattie, E.E.3
  • 63
    • 0030833070 scopus 로고    scopus 로고
    • Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia
    • Teppema LJ, Veening JG, Kranenburg A, Dahan A, Berkenbosch A, Olievier C (1997) Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia. J Comp Neurol 388:169-190
    • (1997) J Comp Neurol , vol.388 , pp. 169-190
    • Teppema, L.J.1    Veening, J.G.2    Kranenburg, A.3    Dahan, A.4    Berkenbosch, A.5    Olievier, C.6
  • 64
  • 65
    • 0023276521 scopus 로고
    • A blood pressure lowering effect of lesions of the caudal periaqueductal gray: Relationship to basal pressure
    • 1-2
    • Ward DG, Darlington DN (1987) A blood pressure lowering effect of lesions of the caudal periaqueductal gray: relationship to basal pressure. Brain Res 423(1-2):373-377
    • (1987) Brain Res , vol.423 , pp. 373-377
    • Ward, D.G.1    Darlington, D.N.2
  • 66
    • 17444454333 scopus 로고
    • Cardiovascular effect of V1 vasopressinergic blockade during acute hypercapnia in conscious rats
    • 1
    • Walker BR (1987) Cardiovascular effect of V1 vasopressinergic blockade during acute hypercapnia in conscious rats. Am J Physiol 252(1):R127-133
    • (1987) Am J Physiol , vol.252 , pp. 127-133
    • Walker, B.R.1
  • 67
    • 34147151295 scopus 로고    scopus 로고
    • Carbon dioxide and pH effects on temperature-sensitive and -insensitive hypothalamic neurons
    • 4
    • Wright CL, Boulant JA (2007) Carbon dioxide and pH effects on temperature-sensitive and -insensitive hypothalamic neurons. J Appl Physiol 102(4):1357-1366
    • (2007) J Appl Physiol , vol.102 , pp. 1357-1366
    • Wright, C.L.1    Boulant, J.A.2
  • 68
    • 0037436540 scopus 로고    scopus 로고
    • Effect of indomethacin on the c-fos expression in AVP and TH neurons in rat brain induced by lipopolysaccharide
    • Xu S, Guo S, Jiang X, Yin Q, Umezawa T, Hisamitsu T (2003) Effect of indomethacin on the c-fos expression in AVP and TH neurons in rat brain induced by lipopolysaccharide. Brain Res 966:13-18
    • (2003) Brain Res , vol.966 , pp. 13-18
    • Xu, S.1    Guo, S.2    Jiang, X.3    Yin, Q.4    Umezawa, T.5    Hisamitsu, T.6
  • 69
    • 0032960186 scopus 로고    scopus 로고
    • Nitrergic stimulation of the locus coeruleus modulates blood pressure and heart rate in the anaesthetized rat
    • 2
    • Yao ST, Finkelstein DI, Lawrence AJ (1999) Nitrergic stimulation of the locus coeruleus modulates blood pressure and heart rate in the anaesthetized rat. Neuroscience 91(2):621-629
    • (1999) Neuroscience , vol.91 , pp. 621-629
    • Yao, S.T.1    Finkelstein, D.I.2    Lawrence, A.J.3
  • 70
    • 21244433608 scopus 로고    scopus 로고
    • Purinergic modulation of cardiovascular function in the rat locus coeruleus
    • 3
    • Yao ST, Lawrence AJ (2005) Purinergic modulation of cardiovascular function in the rat locus coeruleus. Br. J. Pharmacol 145(3):342-352
    • (2005) Br. J. Pharmacol , vol.145 , pp. 342-352
    • Yao, S.T.1    Lawrence, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.