Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation

Journal of Comparative Neurology

Volumn 499, Issue 5, 2006, Pages 840-859

  Card, J Patrick ^a   Sved, Judy C ^a   Craig, Brian ^a   Raizada, Mohan ^b   Vazquez, Jorge ^b,c   Sved, Alan F ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Dopamine hydroxylase synthetic promoter; Lentivirus vector; Phenotypically defined anterograde tracing

Indexed keywords

DOPAMINE BETA MONOOXYGENASE; ENHANCED GREEN FLUORESCENT PROTEIN;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BRAIN STEM; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR RESPONSE; CATECHOLAMINE NERVE CELL; CONTROLLED STUDY; DIENCEPHALON; EFFERENT NERVE; HYPOTHALAMUS NUCLEUS; LENTIVIRUS VECTOR; LOCUS CERULEUS; MALE; MESENCEPHALON; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT;

EID: 33750910876     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.21140     Document Type: Article

References (53)

1. Adams JC. 1981. Heavy metal intensification of DAB-based HRP reaction product. J Histochem Cytochem 29:225.
2. Barman SM, Gebber GL. 1987. Lateral tegmental field neurons of cat medulla: a source of basal activity of ventrolateral medullospinal sympathoexcitatory neurons. J Neurophysiol 57:1410-1424.
3. Ben-Barak Y, Russell JT, Whitnall MH, Ozato K, Gainer H. 1985. Neurophysin in the hypothalamo-neurohypophysial system. I. Production and characterization of monoconal antibodies. J Neurosci 5:81-97.
4. Billig I, Foris JM, Enquist LW, Card JP, Yates BJ. 2000. Definition of neuronal circuitry controlling the activity of phrenic and abdominal motoneurons in the ferret using recombinant strains of pseudorabies virus. J Neurosci 20:7446-7454.
5. Blessing WW, Hedger SC, Joh TH, Willoughby JO. 1987. Neurons in the area postrema are the only catecholamine-synthesizing cells in the medulla or pons with projections to the rostral ventrolateral medulla (C1-area) in the rabbit. Brain Res 419:336-340.
6. Cano G, Sved AF, Rinaman L, Rabin BS, Card JP. 2001. Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing. J Comp Neurol 439:1-18.
7. Card JP, Enquist LW. 1999. Transneuronal circuit analysis with pseudorabies viruses. In: Crawley JN, Gerfen CR, McKay R, Rogawski MA, Sibley DR, Skolnick P, editors. Current Protocols in Neuroscience. San Diego: John Wiley & Sons. p 1.5.1-1.5.28.
8. Cavun S, Millington WR. 2001. Evidence that hemorrhagic hypotension is mediated by the ventrolateral periaqueductal gray region. Am J Physiol 281:R747-R752.
9. Coleman JE, Huentelman MJ, Kasparov S, Metcalfe BL, Paton JFR, Katovich MJ, Semple-Rowland SL, Raizada MK. 2003. Efficient large-scale production and concentration of HIV-1 based lentiviral vectors for use in vivo. Physiol Genom 12:221-228.
10. Cui Y, Iwakuma T, Chang LJ. 1999. Contributions of viral splice sites and cis-regulatory elements to lentivirus vector function. J Virol 73:6171-6176.
11. Cunningham ET, Bohn MC, Sawchenko PE. 1990. Organization of the adrenergic inputs to the paraventricular and supraoptic nuclei of the hypothalamus in the rat. J Comp Neurol 292:651-667.
12. Dampney RAL. 1994. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 74:323-364.
13. Fekete C, Sarkar S, Lechan RM. 2005. Relative contribution of brainstem afferents to the cocaine- and amphetamine-related transcript (CART) innervation of thyrotropin-releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus (PVN). Brain Res 1032:171-175.
14. Grinevich V, Brecht M, Osten P. 2005. Monosynaptic pathway from rat vibrissa motor cortex to facial motor neurons revealed by lentivirus-based axonal tracing. J Neurosci 25:8250-8258.
15. Guyenet PG, Young BS. 1987. Projections of nucleus paragigantocellularis lateralis to locus coeruleus and other structures in rat. Brain Res 406:171-184.
16. Haselton JR, Guyenet PG. 1989. Electrophysiological characterization of putative C1 adrenergic neurons in the rat. Neuroscience 30:199-214.
17. Haselton JR, Guyenet PG. 1990. Ascending collaterals of medullary barosensitive neurons and C1 cells in rats. Am J Physiol 258:1051-1063.
18. Herbert H, Saper CB. 1992. Organization of medullary adrenergic and noradrenergic projections to the periaqueductal gray matter in the rat. J Comp Neurol 315:34-52.
19. Hopkins DA. 1995. Ultrastructure and synaptology of the nucleus ambiguus in the rat: the compact formation. J Comp Neurol 360:705-725.
20. Hwang D-Y, Carlezon WA, Isacson O, Kim K-S. 2001. A high-efficiency synthetic promotoer that drives transgene expression selectively in noradrenergic neurons. Hum Gene Ther 12:1731-1740.
21. Iwakuma T, Cui L-N, Chang LJ. 1999. Self-inactivating lentiviral vectors with U3 and U5 modifications. Virology 261:120-132.
22. Jeske I, McKenna KE. 1992. Quantitative analysis of bulbospinal projections from the rostral ventrolateral medulla-contribution of C1-adrenergic and nonadrenergic neurons. J Comp Neurol 324:1-13.
23. Madden CJ, Sved AF. 2003. Cardiovascular regulation after destruction of the C1 cell group of the rostral ventrolateral medulla in rats. Am J Physiol 285:2734-2748.
24. Madden CJ, Ito S, Rinaman L, Wiley RG, Sved AF. 1999. Lesions of the C1 catecholaminergic neurons of the ventrolateral medulla in rats using anti-DβH-saporin. Am J Physiol 46:R1063-R1075.
25. McLean IW, Nakane PK 1974. Periodate-lysine-paraformaldehyde fixative. A new fixative for immunoelectron microscopy. J Histochem Cytochem 22:1077-1083.
26. Okada Y, Chen Z, Jiang W, Kuwana S, Eldridge FL. 2002. Anatomical arrangement of hypercapnia-activated cells in the superficial ventral medulla of rats. J Appl Physiol 93:427-439.
27. Pieribone VA, Aston-Jones G, Bohn MC. 1988. Adrenergic and nonadrenergic neurons in the C1 and C3 areas project to locus coeruleus: a fluorescent double labeling study. Neurosci Lett 85:297-303.
28. Rinaman L. 1998. Oxytocinergic inputs to the nucleus of the solitary tract and dorsal motor nucleus of the vagus in neonatal rats. J Comp Neurol 399:101-109.
29. Rinaman L. 2001. Postnatal development of catecholamine inputs to the paraventricular nucleus of the hypothalamus in rats. J Comp Neurol 438:411-422.
30. Rinaman L, Card JP, Enquist LW. 1993. Spatiotemporal responses of astrocytes, ramified microglia, and brain macrophages to central neuronal infection with pseudorabies virus. J Neurosci 13:685-702.
31. Ross CA, Armstrong DM, Ruggiero DA, Pickel VM, Joh TH, Reis DJ. 1981. Adrenaline neurons in the rostral ventrolateral medulla innervate thoracic spinal cord: a combined immunocytochemical and retrograde transport demonstration. Neurosci Lett 25:257-262.
32. Ross CA, Ruggiero DA, Joh TH, Park DH, Reis DJ. 1984a. Rostral ventrolateral medulla: selective projections to the thoracic autonomic cell column from the region containing C1 adrenergic neurons. J Comp Neurol 228:168-185.
33. Ross CA, Ruggiero DA, Meeley MP, Park DH, Joh TH, Reis DJ. 1984b. A new group of neurons in hypothalamus containing phenylethanolamine N-methyltransferase (PNMT) but not tyrosine hydroxylase. Brain Res 306:349-353.
34. Ruggiero DA, Ross CA, Anwar M, Park DH, Joh TH, Reis DJ. 1985. Distribution of neurons containing phenylethanolamine N-methyltransferase in medulla and hypothalamus of rat. J Comp Neurol 239:127-154.
35. Saper CB, Reis DJ, Joh TH. 1983. Medullary catecholamine inputs to the anteroventral third ventricular cardiovascular region in the rat. Neurosci Lett 42:285-292.
36. Sawchenko PE, Swanson LW. 1981. Central noradrenergic pathways for the integration of hypothalamic neuroendorine and autonomic responses. Science 214:685-687.
37. Sawchenko PE, Swanson LW, Grzanna R, Howe PRC, Bloom SR, Polak JM. 1985. Colocalization of neuropeptide Y immunoreactivity in brain-stem catecholamine neurons that project to the paraventricular nucleus of hypothalamus. J Comp Neurol 241:138-153.
38. Schadt JC, Shafford HL, McKnown MD. 2005. Neuronal activity within the ventrolateral periaqueductal gray during simulated hemorrhage in conscious rabbits. Am J Physiol 290:R715-R725.
39. Schreihofer AM, Guyenet PG. 2000a. Role of presympathetic C1 neurons in the sympatholytic and hypotensive effects of clonidine in rats. Am J Physiol 279:R1753-R1762.
40. Schreihofer AM, Guyenet PG. 2000b. Sympathetic reflexes after depletion of bulbospinal catecholaminergic neurons with anti-DβH-saporin. Am J Physiol 279:R729-R742.
41. Schreihofer AM, Stornetta R, Guyenet PG. 2000. Regulation of sympathetic tone and arterial pressure by rostral ventrolateal medulla after depletion of C1 cells in rats. J Physiol 529:221-236.
42. Shapiro RE, Miselis RR. 1985. The central organization of the vagus nerve innervating the stomach of the rat. J Comp Neurol 238:473-488.
43. Simerly RB, Swanson LW. 1986. The organization of neural inputs to the medial preoptic nucleus of the rat. J Comp Neurol 246:312-342.
44. Stornetta R, Akey PJ, Guyenet PG. 1999. Location and electrophysiological characterization of rostral medullary adrenergic neurons that contain neuropeptide Y mRNA in rat medulla. J Comp Neurol 415:482-500.
45. Sun MK, Guyenet PG. 1986. Effect of clonidine and gama-aminobutyric acid on the discharges of medullo-spinal sympathoexcitatory neurons in the rat brain. Brain Res 368:1-17.
46. Swanson LW. 1998. Brain maps: structure of the rat brain. Amsterdam: Elsevier.
47. Thor KB, Heike CJ. 1988. Catecholamine-synthesizing neuronal projections to the nucleus tractus solitarii of the rat. J Comp Neurol 268: 264-280.
48. Tiveron M-C, Hirsch M-R, Brunet J-F. 1996. The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system. J Neurosci 16:7649-7660.
49. Tucker DC, Saper CB, Ruggiero DA, Reis DJ. 1987. Organization of central adrenergic pathways: I. Relationships of ventrolateral medullary projections to the hypothalamus and spinal cord. J Comp Neurol 259:591-603.
50. Van Bockstaele E, Pieribone VA, Aston-Jones G. 1989. Diverse afferents converge on the nucleus paragigantocellularis in the rat ventrolateral medulla: retrograde and anterograde tracing studies. J Comp Neurol 290:561-584.
51. Watson RE, Wiegand ST, Clough RW, Hoffman GE. 1986. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 7:155-159.
52. Weston MC, Stornetta RL, Guyenet PG. 2004. Glutamatergic neuronal projections from the marginal layer of the rostral ventral medulla to the respiratory centers in rats. J Comp Neurol 473:73-85.
53. Whitnall MH, Key S, Ben-Barak Y, Ozato K, Gainer H. 1985. Neurophysin in the hypothalamic-neurohypophysial system. II. Immunocytochemical studies of the ontogeny of oxytocinergic and vasopressinergic neurons. J Neurosci 5:98-109.