Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 2, 2008, Pages 431-436

  Cheng, Ting Jen Rachel ^a   Sung, Ming Ta ^a   Liao, Hsin Yu ^a   Chang, Yi Fan ^a   Chen, Chia Wei ^a   Huang, Chia Ying ^a   Chou, Lien Yang ^a   Wu, Yen Da ^a   Chen, Yin Hsuan ^a   Cheng, Yih Shyun E ^a   Wong, Chi Huey ^a   Ma, Che ^a   Cheng, Wei Chieh ^a  

^a GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

Fluorescence anisotropy; Penicillin binding proteins; Transglycosylase inhibitors

Indexed keywords

BAMBERMYCIN; GLYCOSYLTRANSFERASE; PENICILLIN BINDING PROTEIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL GROWTH; BINDING AFFINITY; DRUG INHIBITION; DRUG STRUCTURE; ENTEROCOCCUS FAECALIS; HIGH THROUGHPUT SCREENING; MINIMUM INHIBITORY CONCENTRATION; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; SURFACE PLASMON RESONANCE; SYNTHESIS;

ANISOTROPY; CELL WALL; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; ENTEROCOCCUS FAECALIS; GLYCOSYLTRANSFERASES; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, CHEMICAL; OLIGOSACCHARIDES; PENICILLIN-BINDING PROTEINS; SPECTROMETRY, FLUORESCENCE; STAPHYLOCOCCUS AUREUS; SURFACE PLASMON RESONANCE; TECHNOLOGY, PHARMACEUTICAL;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; STAPHYLOCOCCUS AUREUS;

EID: 38649087623     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710868105     Document Type: Article

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