Microplate assay for inhibitors of the transpeptidase activity of PBP1b of Escherichia coli

Journal of Biomolecular Screening

Volumn 11, Issue 8, 2006, Pages 1005-1014

  Jha, Ramesh K ^a,b   De Sousa, Sunita M ^a  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cross linking; PBP; Peptidoglycan; SPA; Transpeptidase

Indexed keywords

AMPICILLIN; ANTIINFECTIVE AGENT; BAMBERMYCIN; BETA LACTAM ANTIBIOTIC; CEFALEXIN; CEFRADINE; ENZYME INHIBITOR; ESCHERICHIA COLI PROTEIN; GAMMA GLUTAMYLTRANSFERASE; GLYCOSYLTRANSFERASE; GLYCOSYLTRANSFERASE INHIBITOR; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 1B; PENICILLIN G; PEPTIDOGLYCAN; SARCOSINE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID; WHEAT GERM AGGLUTININ;

ARTICLE; BACTERIAL MEMBRANE; BINDING AFFINITY; CHROMATOGRAPHY; CONTROLLED STUDY; DILUTION; DRUG BINDING; DRUG INHIBITION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; ISOTOPE LABELING; MICRODILUTION PLATE METHOD; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; SCINTILLATION;

BACTERIAL PROTEINS; BIOLOGICAL ASSAY; CELL MEMBRANE; CHROMATOGRAPHY, PAPER; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; ESCHERICHIA COLI; PENICILLIN-BINDING PROTEINS; PEPTIDOGLYCAN; PEPTIDYL TRANSFERASES; TIME FACTORS;

ESCHERICHIA COLI; TRITICUM AESTIVUM;

EID: 33751563480     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057106294364     Document Type: Article

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