Tubulin-perturbing naphthoquinone spiroketals

Chemical Biology and Drug Design

Volumn 71, Issue 2, 2008, Pages 117-124

  Balachandran, Raghavan ^a   Hopkins, Tamara D ^a   Thomas, Catherine A ^a   Wipf, Peter ^a   Day, Billy W ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Hsp70; Microtubules; p21WAF1; Thioredoxin reductase

Indexed keywords

5' HYDROXY 4'H SPIRO[1,3 DIOXOLANE 2,1' NAPHTHALEN] 4' ONE; 5' METHOXY 4'H SPIRO[1,3 DIOXANE 2,1' NAPHTHALEN] 4' ONE; [8 (FURAN 3 YLMETHOXY) 1 OXO 1,4 DIHYDRONAPHTHALENE 4 SPIRO 2' NAPHTHO[1',8' DE][1',3] [DIOXIN]; BETA TUBULIN; COLCHICINE; NAPHTHOQUINONE; PACLITAXEL; SR 7; TH 169; TH 223; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; NEOPLASM; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DRUG SCREENING ASSAYS, ANTITUMOR; FURANS; GUANOSINE TRIPHOSPHATE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; NAPHTHOQUINONES; PACLITAXEL; SPIRO COMPOUNDS; TUBULIN; UP-REGULATION;

EID: 38549166138     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2007.00616.x     Document Type: Article

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