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1
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16044365022
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Alfred P. Sloan Research Fellow, 1994-1996; NSF Presidential Faculty Fellow, 1994-1999; Camille Dreyfus Teacher-Scholar, 1995-1997.
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Alfred P. Sloan Research Fellow, 1994-1996; NSF Presidential Faculty Fellow, 1994-1999; Camille Dreyfus Teacher-Scholar, 1995-1997.
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2
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0028258027
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Gerwick, W. H.; Proteau, P. J.; Nagle, D. G.; Harvel, E.; Blokhin, A.; Slate, D. J. Org. Chem. 1994, 59, 1243.
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(1994)
J. Org. Chem.
, vol.59
, pp. 1243
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Gerwick, W.H.1
Proteau, P.J.2
Nagle, D.G.3
Harvel, E.4
Blokhin, A.5
Slate, D.6
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3
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0029014405
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(a) White, J. D.; Kim, T.-S.; Nambu, M. J. Am. Chem. Soc. 1995, 117, 5612.
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(1995)
J. Am. Chem. Soc.
, vol.117
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White, J.D.1
Kim, T.-S.2
Nambu, M.3
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4
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0028860085
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(b) Nagle, D. G.; Geralds, R. S.; Yoo, H.-D.; Gerwick, W. H.; Kim, T.-S.; Nambu, M.; White, J. D. Tetrahedron Lett. 1995, 36, 1189.
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(1995)
Tetrahedron Lett.
, vol.36
, pp. 1189
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Nagle, D.G.1
Geralds, R.S.2
Yoo, H.-D.3
Gerwick, W.H.4
Kim, T.-S.5
Nambu, M.6
White, J.D.7
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5
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85047675015
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(c) Onoda, T.; Shirai, R.; Koiso, Y.; Iwasaki, S. Tetrahedron Lett. 1995, 36, 5765.
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(1995)
Tetrahedron Lett.
, vol.36
, pp. 5765
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Onoda, T.1
Shirai, R.2
Koiso, Y.3
Iwasaki, S.4
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6
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0030039761
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(d) Hoemann, M. Z.; Agrios, K. A.; Aubé, J. Tetrahedron Lett. 1996, 37, 953.
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(1996)
Tetrahedron Lett.
, vol.37
, pp. 953
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Hoemann, M.Z.1
Agrios, K.A.2
Aubé, J.3
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7
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0029876710
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(e) Ito, H.; Imai, N.; Tanikawa, S.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 1795.
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(1996)
Tetrahedron Lett.
, vol.37
, pp. 1795
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Ito, H.1
Imai, N.2
Tanikawa, S.3
Kobayashi, S.4
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8
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0029925251
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(f) Ito, H.; Imai, N.; Takao, K.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 1799.
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(1996)
Tetrahedron Lett.
, vol.37
, pp. 1799
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Ito, H.1
Imai, N.2
Takao, K.3
Kobayashi, S.4
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9
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0029098439
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Blokhin, A. V.; Yoo, H. D.; Geralds, R. S.; Nagle, D. G.; Gerwick, W. H.; Hamel, E. Mol. Pharm. 1995, 48, 523.
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(1995)
Mol. Pharm.
, vol.48
, pp. 523
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Blokhin, A.V.1
Yoo, H.D.2
Geralds, R.S.3
Nagle, D.G.4
Gerwick, W.H.5
Hamel, E.6
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10
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0000853969
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For representative structures, see: (a) Davidson, B. S. Chem. Rev. 1993, 93, 1771.
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(1993)
Chem. Rev.
, vol.93
, pp. 1771
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Davidson, B.S.1
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11
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0000314051
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(b) Wipf, P. Chem. Rev. 1995, 95, 2115.
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(1995)
Chem. Rev.
, vol.95
, pp. 2115
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Wipf, P.1
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12
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0030131103
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and references cited therein
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(c) Faulkner, D. J. Nat. Prod. Rep. 1996, 13, 75 and references cited therein.
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(1996)
Nat. Prod. Rep.
, vol.13
, pp. 75
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Faulkner, D.J.1
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13
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0029163117
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(a) Wipf, P.; Miller, C. P.; Venkatraman, S.; Fritch, P. C. Tetrahedron Lett. 1995, 36, 6395.
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(1995)
Tetrahedron Lett.
, vol.36
, pp. 6395
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Wipf, P.1
Miller, C.P.2
Venkatraman, S.3
Fritch, P.C.4
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19
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84982433710
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Schwartz, J.; Labinger, J. A. Angew. Chem., Int. Ed. Engl. 1976, 15, 333.
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(1976)
Angew. Chem., Int. Ed. Engl.
, vol.15
, pp. 333
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Schwartz, J.1
Labinger, J.A.2
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20
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0000395519
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Trost, B. M., Fleming, I., Eds.; Pergamon: Oxford
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(a) Labinger, J. A. In Comprehensive Organic Synthesis; Trost, B. M., Fleming, I., Eds.; Pergamon: Oxford, 1991; Vol. 8, pp 667-702.
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(1991)
Comprehensive Organic Synthesis
, vol.8
, pp. 667-702
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Labinger, J.A.1
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23
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0001314965
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(b) Cacchi, S.; Morera, E.; Ortar, G. Tetrahedron Lett. 1984, 25, 4821.
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(1984)
Tetrahedron Lett.
, vol.25
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Cacchi, S.1
Morera, E.2
Ortar, G.3
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28
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0000741028
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Negishi, E.; Swanson, D. R.; Miller, S. R. Tetrahedron Lett. 1988, 29, 1631.
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(1988)
Tetrahedron Lett.
, vol.29
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Negishi, E.1
Swanson, D.R.2
Miller, S.R.3
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30
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16044363796
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note
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The enantiomeric excess of the homoallylic alcohol 13 was determined as 93% by Mosher ester analysis.
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31
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0028887072
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(a) Charette, A. B.; Prescott, S.; Brochu, C. J. Org. Chem. 1995, 60, 1081.
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(1995)
J. Org. Chem.
, vol.60
, pp. 1081
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Charette, A.B.1
Prescott, S.2
Brochu, C.3
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36
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0029077940
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For a related, successful partial reduction of a thiazolyl ester, see: Rinehart, K. L.; Staley, A. L.; Wilson, S. R.; Ankenbauer, R. G.; Cox, C. D. J. Org. Chem. 1995, 60, 2786.
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(1995)
J. Org. Chem.
, vol.60
, pp. 2786
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Rinehart, K.L.1
Staley, A.L.2
Wilson, S.R.3
Ankenbauer, R.G.4
Cox, C.D.5
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37
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16044371215
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in press
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The rate of thiolysis of oxazolines correlates roughly with the electron-withdrawing effect of the substituent α to the nitrogen atom. Acceptor, e.g., ester-substituted, oxazolines are generally thiolyzed more readily than unsubstituted or donor-substituted heterocycles: Wipf, P.; Venkatraman, S. Synlett, in press.
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Synlett
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Wipf, P.1
Venkatraman, S.2
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16044366941
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We would like to thank Professor Gerwick for a generous sample of natural curacin A
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We would like to thank Professor Gerwick for a generous sample of natural curacin A.
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40
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16044373476
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note
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3d have also successfully applied the oxazoline→thiazoline strategy in their synthesis of curacin A.
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41
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16044369254
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note
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3d
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