Negative feedback loop in the Bim-caspase-3 axis regulating apoptosis and activity of osteoclasts

Journal of Bone and Mineral Research

Volumn 22, Issue 10, 2007, Pages 1631-1639

  Wakeyama, Hidetoshi ^a   Akiyama, Toru ^a   Takahashi, Katsuhiko ^b   Amano, Hitoshi ^b   Kadono, Yuho ^a   Nakamura, Masaki ^a   Oshima, Yasushi ^a   Itabe, Hiroyuki ^b   Nakayama, Keiichi I ^c   Nakayama, Keiko ^d   Nakamura, Kozo ^a   Tanaka, Sakae ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SHOWA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Bim; c Cbl; Caspase 3; Degradation; Osteoclast

Indexed keywords

ACTIN; BIM PROTEIN; CASPASE 3; CASPASE 7; CATHEPSIN K; CBL PROTEIN; PROTEASOME; PROTEIN BCL 2; UBIQUITIN; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; MEMBRANE PROTEIN; ONCOPROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BONE MARROW CELL; CASPASE 3 GENE; CASPASE 7 GENE; CELL ACTIVITY; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITION; GENE; LIFESPAN; MITOCHONDRION; NEGATIVE FEEDBACK; OSTEOCLAST; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; ANIMAL; CELL LINE; CYTOLOGY; DOWN REGULATION; ENZYMOLOGY; FEEDBACK SYSTEM; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASE 7; CELL LINE; DOWN-REGULATION; ENZYME ACTIVATION; FEEDBACK, BIOCHEMICAL; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; OSTEOCLASTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CBL;

EID: 38449119999     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.070619     Document Type: Article

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