-
1
-
-
0024601010
-
PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
-
Auger K.R., Serunian L.A., Soltoff S.P., Libby P., and Cantley L..C. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57 (1989) 167-175
-
(1989)
Cell
, vol.57
, pp. 167-175
-
-
Auger, K.R.1
Serunian, L.A.2
Soltoff, S.P.3
Libby, P.4
Cantley, L..C.5
-
2
-
-
2942748149
-
Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle
-
Barker C.J., Wright J., Hughes P.J., Kirk C.J., and Michell R.H. Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle. Biochem. J. 380 (2004) 465-473
-
(2004)
Biochem. J.
, vol.380
, pp. 465-473
-
-
Barker, C.J.1
Wright, J.2
Hughes, P.J.3
Kirk, C.J.4
Michell, R.H.5
-
3
-
-
0027991781
-
Phosphatidylinositol 3,4,5-trisphosphate is formed from phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets
-
Carter A.N., Huang R., Sorisky A., Downes C.P., and Rittenhouse S.E. Phosphatidylinositol 3,4,5-trisphosphate is formed from phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets. Biochem. J. 301 (1994) 415-420
-
(1994)
Biochem. J.
, vol.301
, pp. 415-420
-
-
Carter, A.N.1
Huang, R.2
Sorisky, A.3
Downes, C.P.4
Rittenhouse, S.E.5
-
4
-
-
23744492188
-
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils
-
Condliffe A.M., Davidson K., Anderson K.E., Ellson C.D., Crabbe T., Okkenhaug K., Vanhaesebroeck B., Turner M., Webb L., Wymann M.P., Hirsch E., Ruckle T., et al. Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood 106 (2005) 1432-1440
-
(2005)
Blood
, vol.106
, pp. 1432-1440
-
-
Condliffe, A.M.1
Davidson, K.2
Anderson, K.E.3
Ellson, C.D.4
Crabbe, T.5
Okkenhaug, K.6
Vanhaesebroeck, B.7
Turner, M.8
Webb, L.9
Wymann, M.P.10
Hirsch, E.11
Ruckle, T.12
-
5
-
-
0020521860
-
Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones
-
Creba J.A., Downes C.P., Hawkins P.T., Brewster G., Mitchell R.H., and Kirk C.J. Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones. Biochem. J. 212 (1983) 733-747
-
(1983)
Biochem. J.
, vol.212
, pp. 733-747
-
-
Creba, J.A.1
Downes, C.P.2
Hawkins, P.T.3
Brewster, G.4
Mitchell, R.H.5
Kirk, C.J.6
-
6
-
-
0035975965
-
Modular phosphoinositide-binding domains: Their role in signalling and membrane trafficking
-
Cullen P.J., Cozier G.E., Banting G., and Mellor H. Modular phosphoinositide-binding domains: Their role in signalling and membrane trafficking. Curr. Biol. 11 (2001) 882-893
-
(2001)
Curr. Biol.
, vol.11
, pp. 882-893
-
-
Cullen, P.J.1
Cozier, G.E.2
Banting, G.3
Mellor, H.4
-
7
-
-
33644513730
-
Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
Cully M., You H., Levine A.J., and Mak T.W. Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat. Rev. Cancer 6 (2006) 4-92
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 4-92
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
8
-
-
0037006803
-
Type I PIP kinases interact with and are regulated by the retinoblastoma susceptibility gene product-pRB
-
Divecha N., Roefs M., Los A., Halstead J., Bannister A., and D'Santos C. Type I PIP kinases interact with and are regulated by the retinoblastoma susceptibility gene product-pRB. Curr. Biol. 12 (2002) 582-587
-
(2002)
Curr. Biol.
, vol.12
, pp. 582-587
-
-
Divecha, N.1
Roefs, M.2
Los, A.3
Halstead, J.4
Bannister, A.5
D'Santos, C.6
-
9
-
-
35348812273
-
Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes
-
Chap. 8 (this volume)
-
Donahue A.C., Kharas M.G., and Fruman D.A. Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes. Methods Enzymol 434 (2007) Chap. 8 (this volume)
-
(2007)
Methods Enzymol
, vol.434
-
-
Donahue, A.C.1
Kharas, M.G.2
Fruman, D.A.3
-
10
-
-
0034306455
-
Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities
-
Dowler S., Currie R.A., Campbell D.G., Deak M., Kular G., Downes C.P., and Alessi D.R. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem. J. 351 (2000) 19-31
-
(2000)
Biochem. J.
, vol.351
, pp. 19-31
-
-
Dowler, S.1
Currie, R.A.2
Campbell, D.G.3
Deak, M.4
Kular, G.5
Downes, C.P.6
Alessi, D.R.7
-
12
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman J.A., Luo J., and Cantley L.C. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 7 (2006) 606-619
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
13
-
-
33745667306
-
Thin layer chromatography-blotting, a novel method for the detection of phosphoinositides
-
Furutani M., Itoh T., Ijuin T., Tsujita K., and Takenawa T. Thin layer chromatography-blotting, a novel method for the detection of phosphoinositides. J. Biochem 139 (2006) 163-170
-
(2006)
J. Biochem
, vol.139
, pp. 163-170
-
-
Furutani, M.1
Itoh, T.2
Ijuin, T.3
Tsujita, K.4
Takenawa, T.5
-
14
-
-
33646705667
-
Regulation of PTEN phosphatase
-
Gericke A., Munson M., and Ross A.H. Regulation of PTEN phosphatase. Gene 374 (2006) 1-9
-
(2006)
Gene
, vol.374
, pp. 1-9
-
-
Gericke, A.1
Munson, M.2
Ross, A.H.3
-
15
-
-
0037442448
-
Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts
-
Gray A., Olsson H., Batty I.H., Priganica L., and Downes C.P. Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts. Anal. Biochem. 313 (2003) 234-245
-
(2003)
Anal. Biochem.
, vol.313
, pp. 234-245
-
-
Gray, A.1
Olsson, H.2
Batty, I.H.3
Priganica, L.4
Downes, C.P.5
-
16
-
-
0033572662
-
The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo
-
Gray A., Van der Kaay J., and Downes C.P. The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo. Biochem. J. 344 (1999) 929-936
-
(1999)
Biochem. J.
, vol.344
, pp. 929-936
-
-
Gray, A.1
Van der Kaay, J.2
Downes, C.P.3
-
17
-
-
33947174209
-
Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach
-
Guillou H., Lécureuil C., Anderson K.E., Suire S., Ferguson G.J., Ellson C.D., Gray A., Divecha N., Hawkins P.T., and Stephens L.R. Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach. J. Lipid Res. 48 (2007) 726-732
-
(2007)
J. Lipid Res.
, vol.48
, pp. 726-732
-
-
Guillou, H.1
Lécureuil, C.2
Anderson, K.E.3
Suire, S.4
Ferguson, G.J.5
Ellson, C.D.6
Gray, A.7
Divecha, N.8
Hawkins, P.T.9
Stephens, L.R.10
-
19
-
-
33748462297
-
Membrane binding domains
-
Hurley J.H. Membrane binding domains. Biochim. Biophys. Acta 1761 (2006) 805-811
-
(2006)
Biochim. Biophys. Acta
, vol.1761
, pp. 805-811
-
-
Hurley, J.H.1
-
20
-
-
0026674617
-
Receptor specificity of growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells
-
Jackson T.R., Stephens L.R., and Hawkins P.T. Receptor specificity of growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells. J. Biol. Chem. 267 (1992) 16627-16636
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16627-16636
-
-
Jackson, T.R.1
Stephens, L.R.2
Hawkins, P.T.3
-
21
-
-
0036033109
-
SHIP represses mast cell activation and reveals that IgE alone triggers signaling pathways which enhance normal mast cell survival
-
Kalesnikoff J., Lam V., and Krystal G. SHIP represses mast cell activation and reveals that IgE alone triggers signaling pathways which enhance normal mast cell survival. Mol. Immunol. 38 (2002) 1201-1206
-
(2002)
Mol. Immunol.
, vol.38
, pp. 1201-1206
-
-
Kalesnikoff, J.1
Lam, V.2
Krystal, G.3
-
22
-
-
0032515042
-
Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains
-
Kavran J.M., Klein D.E., Lee A., Falasca M., Isakoff S.J., Skolnik E.Y., and Lemmon M.A. Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains. J. Biol. Chem. 273 (1998) 30497-30508
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30497-30508
-
-
Kavran, J.M.1
Klein, D.E.2
Lee, A.3
Falasca, M.4
Isakoff, S.J.5
Skolnik, E.Y.6
Lemmon, M.A.7
-
23
-
-
0024564637
-
Determination of the steady-state turnover rates of the metabolically active pools of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in human erythrocytes
-
King C.E., Hawkins P.T., Stephens L.R., and Michell R.H. Determination of the steady-state turnover rates of the metabolically active pools of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in human erythrocytes. Biochem. J. 259 (1989) 893-896
-
(1989)
Biochem. J.
, vol.259
, pp. 893-896
-
-
King, C.E.1
Hawkins, P.T.2
Stephens, L.R.3
Michell, R.H.4
-
24
-
-
0038281249
-
Phosphoinositide recognition domains
-
Lemmon M.A. Phosphoinositide recognition domains. Traffic 4 (2003) 201-213
-
(2003)
Traffic
, vol.4
, pp. 201-213
-
-
Lemmon, M.A.1
-
25
-
-
33845972919
-
Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression
-
Lindsay Y., McCoull D., Davidson L., Leslie N.R., Fairservice A., Gray A., Lucocq J., and Downes C.P. Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression. J. Cell. Sci. 119 (2006) 5160-5168
-
(2006)
J. Cell. Sci.
, vol.119
, pp. 5160-5168
-
-
Lindsay, Y.1
McCoull, D.2
Davidson, L.3
Leslie, N.R.4
Fairservice, A.5
Gray, A.6
Lucocq, J.7
Downes, C.P.8
-
26
-
-
0019640694
-
Chromatography of acidic phospholipids on immobilized neomycin
-
Palmer F.B. Chromatography of acidic phospholipids on immobilized neomycin. J. Lipid Res. 22 (1981) 1296-1300
-
(1981)
J. Lipid Res.
, vol.22
, pp. 1296-1300
-
-
Palmer, F.B.1
-
27
-
-
0018167442
-
Purification of polyphosphoinositides by chromatography on immobilized neomycin
-
Shacht J. Purification of polyphosphoinositides by chromatography on immobilized neomycin. J. Lipid Res. 19 (1978) 1063-1067
-
(1978)
J. Lipid Res.
, vol.19
, pp. 1063-1067
-
-
Shacht, J.1
-
28
-
-
0027366440
-
Agonist-stimulated synthesis of phosphatidylinositol (3,4,5)-trisphosphate: A new intracellular signalling system?
-
Stephens L.R., Jackson T.R., and Hawkins P.T. Agonist-stimulated synthesis of phosphatidylinositol (3,4,5)-trisphosphate: A new intracellular signalling system?. Biochim. Biophys. Acta 1179 (1993) 27-75
-
(1993)
Biochim. Biophys. Acta
, vol.1179
, pp. 27-75
-
-
Stephens, L.R.1
Jackson, T.R.2
Hawkins, P.T.3
-
29
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
Shaw R.J., and Cantley L.C. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441 (2006) 424-430
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
31
-
-
0025731596
-
Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils
-
Stephens L.R., Hughes K.T., and Irvine R.F. Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils. Nature 351 (1991) 33-39
-
(1991)
Nature
, vol.351
, pp. 33-39
-
-
Stephens, L.R.1
Hughes, K.T.2
Irvine, R.F.3
-
32
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
Vanhaesebroeck B., Leevers S.J., Ahmadi K., Timms J., Katso R., Driscoll P.C., Woscholski R., Parker P.J., and Waterfield M.D. Synthesis and function of 3-phosphorylated inositol lipids. Annu. Rev. Biochem. 70 (2001) 535-602
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
33
-
-
0032189234
-
Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain
-
Venkateswarlu K., Gunn-Moore F., Oatey P.B., Tavaré J.M., and Cullen P.J. Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. Biochem. J. 335 (1998) 139-146
-
(1998)
Biochem. J.
, vol.335
, pp. 139-146
-
-
Venkateswarlu, K.1
Gunn-Moore, F.2
Oatey, P.B.3
Tavaré, J.M.4
Cullen, P.J.5
-
34
-
-
0032497832
-
Structure and function of phosphoinositide 3-kinases
-
Wymann M.P., and Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1436 (1998) 127-150
-
(1998)
Biochim. Biophys. Acta
, vol.1436
, pp. 127-150
-
-
Wymann, M.P.1
Pirola, L.2
|