Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach

Journal of Lipid Research

Volumn 48, Issue 3, 2007, Pages 726-732

  Guillou, Hervé ^a   Lécureuil, Charlotte ^a   Anderson, Karen E ^a   Suire, Sabine ^a   Ferguson, G John ^a   Ellson, Chris D ^b   Gray, Alexander ^c   Divecha, Nullin ^d   Hawkins, Phillip T ^a   Stephens, Len R ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

General receptor for phosphoinositides 1; Neomycin; Neutrophil; p110 ; Phosphatidylinositol (3,4,5) trisphosphate; Phosphoinositide 3 kinase; Protein lipid overlay; Ras

Indexed keywords

FORMYLMETHIONYLLEUCYLPHENYLALANINE; GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; RAS PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BINDING SITES; CELL LINE; CELLS, CULTURED; HUMANS; IMMUNOBLOTTING; ISOENZYMES; MICE; MICE, KNOCKOUT; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHOSPHATIDYLINOSITOL PHOSPHATES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SPODOPTERA;

EID: 33947174209     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.D600038-JLR200     Document Type: Article

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