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Volumn , Issue 72, 2007, Pages 105-112

Ginsenoside Rd attenuates neuroinflammation of dopaminergic cells in culture

Author keywords

Dopaminergic; ginsenoside Rd; lipopolysaccharide; neuroinflammation

Indexed keywords

DOPAMINE; GINSENOSIDE; GINSENOSIDE RD; LIPOPOLYSACCHARIDE; NEUROTOXIN; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; TYROSINE 3 MONOOXYGENASE;

EID: 38449083961     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-211-73574-9_13     Document Type: Article
Times cited : (73)

References (33)
  • 1
    • 33745683962 scopus 로고    scopus 로고
    • Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-gamma-stimulated BV-2 microglial cells
    • Bae EA, Kim EJ, Park JS (2006) Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/ interferon-gamma-stimulated BV-2 microglial cells. Planta Med 72(7):627633
    • (2006) Planta Med. , vol.72 , Issue.7 , pp. 627633
    • Bae, E.A.1    Kim, E.J.2    Park, J.S.3
  • 2
    • 0036273352 scopus 로고    scopus 로고
    • Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production
    • Bal-Price A, Matthias A, Brown GC (2002) Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production. J Neurochem 80:73-80
    • (2002) J. Neurochem. , vol.80 , pp. 73-80
    • Bal-Price, A.1    Matthias, A.2    Brown, G.C.3
  • 3
    • 0027280338 scopus 로고
    • Pathological implications of nitric oxide, superoxide and peroxynitrite formation
    • Beckman JS, Crow JP (1993) Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem Soc Trans 21:330-334
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 330-334
    • Beckman, J.S.1    Crow, J.P.2
  • 4
    • 0000073120 scopus 로고    scopus 로고
    • Effect of ginseng saponin in tumor necrosis factor-a production and T cell proliferation
    • Cho JY, Park J, Yoo ES, Baik KU, Park MH (1998) Effect of ginseng saponin in tumor necrosis factor-a production and T cell proliferation. Yakhak Hoegi 43:296-301
    • (1998) Yakhak Hoegi , vol.43 , pp. 296-301
    • Cho, J.Y.1    Park, J.2    Yoo, E.S.3    Baik, K.U.4    Park, M.H.5
  • 5
    • 15244339431 scopus 로고    scopus 로고
    • Development of neonatal murine microglia in vitro: Changes in response to lipopolysaccharide and ischemia-like injury
    • Chock VY, Giffard RG (2005) Development of neonatal murine microglia in vitro: changes in response to lipopolysaccharide and ischemia-like injury. Pediatr Res 57:475-480
    • (2005) Pediatr. Res. , vol.57 , pp. 475-480
    • Chock, V.Y.1    Giffard, R.G.2
  • 6
    • 16344391360 scopus 로고    scopus 로고
    • Effect of ginsenoside Rd on nitric oxide system induced by lipopolysaccharide plus TNF-alpha in C6 rat glioma cells
    • Choi SS, Lee JK, Han EJ, Han KJ, Lee HK (2003) Effect of ginsenoside Rd on nitric oxide system induced by lipopolysaccharide plus TNF-alpha in C6 rat glioma cells. Arch Pharm Res 26:375-382
    • (2003) Arch. Pharm. Res. , vol.26 , pp. 375-382
    • Choi, S.S.1    Lee, J.K.2    Han, E.J.3    Han, K.J.4    Lee, H.K.5
  • 7
    • 0037203948 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: Roles of tumor necrosis factors-a, interleukin-1b, and nitric oxide
    • Gayle DA, Ling ZD, Tong CW, Landers T, Lipton JW (2001) Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factors-a, interleukin-1b, and nitric oxide. Dev Brain Res 133:27-35
    • (2001) Dev. Brain Res. , vol.133 , pp. 27-35
    • Gayle, D.A.1    Ling, Z.D.2    Tong, C.W.3    Landers, T.4    Lipton, J.W.5
  • 8
    • 0033378706 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase
    • Heneka MT, Feinstein DL, Galea E (1999) Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. J Neuroimmunol 100:156-168
    • (1999) J. Neuroimmunol. , vol.100 , pp. 156-168
    • Heneka, M.T.1    Feinstein, D.L.2    Galea, E.3
  • 9
    • 0037378023 scopus 로고    scopus 로고
    • Neuroinflammatory processes in Parkinson's disease
    • Hunot S, Hirsch EC (2003) Neuroinflammatory processes in Parkinson's disease. Ann Neurol 53: S49-S60
    • (2003) Ann. Neurol. , vol.53
    • Hunot, S.1    Hirsch, E.C.2
  • 10
    • 3042683469 scopus 로고    scopus 로고
    • Ginsenoside Rb1: The anti-ulcer constituent from the head of Panax ginseng
    • Jeong CS, Hyun JE, Kim YS (2003) Ginsenoside Rb1: the anti-ulcer constituent from the head of Panax ginseng. Arch Pharm Res 26:906-911
    • (2003) Arch. Pharm. Res. , vol.26 , pp. 906-911
    • Jeong, C.S.1    Hyun, J.E.2    Kim, Y.S.3
  • 11
    • 0029147487 scopus 로고
    • Effect of Panax notoginseng saponins on posthypoxic cell damage of neurons in vitro
    • Jiang KY, Qian ZN (1995) Effect of Panax notoginseng saponins on posthypoxic cell damage of neurons in vitro. Zhongguo Yaoli Xuebao 16:399-402
    • (1995) Zhongguo Yaoli Xuebao , vol.16 , pp. 399-402
    • Jiang, K.Y.1    Qian, Z.N.2
  • 12
    • 0037293063 scopus 로고    scopus 로고
    • Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion
    • Keum YS, Han SS, Chun KS, Park KK (2003) Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion. Mutat Res 523-524:75-85
    • (2003) Mutat Res. , vol.523-524 , pp. 75-85
    • Keum, Y.S.1    Han, S.S.2    Chun, K.S.3    Park, K.K.4
  • 13
    • 16544366501 scopus 로고    scopus 로고
    • Ginsenosides inhibit NMDA receptor-mediated epileptic discharge in cultured hippocampal neurons
    • Kim S, Rhim H (2004) Ginsenosides inhibit NMDA receptor-mediated epileptic discharge in cultured hippocampal neurons. Arch Pharm Res 27:524-530
    • (2004) Arch. Pharm. Res. , vol.27 , pp. 524-530
    • Kim, S.1    Rhim, H.2
  • 15
    • 33745320166 scopus 로고    scopus 로고
    • Pain management today - What have we learned?
    • Langford RM (2006) Pain management today - what have we learned? Clin Rheumatol 25:2-8
    • (2006) Clin. Rheumatol. , vol.25 , pp. 2-8
    • Langford, R.M.1
  • 16
    • 0037363893 scopus 로고    scopus 로고
    • Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice
    • Lee JK, Choi SS, Lee HK, Han KJ, Han EJ, Suh HW (2003) Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice. Planta Med 69:230-234
    • (2003) Planta Med. , vol.69 , pp. 230-234
    • Lee, J.K.1    Choi, S.S.2    Lee, H.K.3    Han, K.J.4    Han, E.J.5    Suh, H.W.6
  • 17
    • 20044389086 scopus 로고    scopus 로고
    • Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammationmediated degeneration of dopaminergic neurons
    • Li FQ, Wang T, Pei Z, Liu B, Hong JS (2005) Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammationmediated degeneration of dopaminergic neurons. J Neural Transm 112:331-347
    • (2005) J. Neural. Transm. , vol.112 , pp. 331-347
    • Li, F.Q.1    Wang, T.2    Pei, Z.3    Liu, B.4    Hong, J.S.5
  • 18
    • 0031291114 scopus 로고    scopus 로고
    • Effect of age and ginsenoside Rg1 on membrance fluidity of cortical cells in rats
    • Li JQ, Zhang JT (1997) Effect of age and ginsenoside Rg1 on membrance fluidity of cortical cells in rats. Yao Xue Xue Bao 32:23-27
    • (1997) Yao Xue Xue Bao , vol.32 , pp. 23-27
    • Li, J.Q.1    Zhang, J.T.2
  • 19
    • 77957357379 scopus 로고    scopus 로고
    • Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
    • Liu B, Hong JS (2003) Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. Trends Pharmacol Sci 24(8):395401
    • (2003) Trends Pharmacol. Sci. , vol.24 , Issue.8 , pp. 395401
    • Liu, B.1    Hong, J.S.2
  • 20
    • 33748633513 scopus 로고    scopus 로고
    • (20S) Rg3 prevents endothelial cells apoptosis via inhibition of the mitochondrial apoptotic caspase pathway
    • Min JK, Kim JH, Cho YL, Kwon YG (2006) (20S) Rg3 prevents endothelial cells apoptosis via inhibition of the mitochondrial apoptotic caspase pathway. Biochem Biophys Res Commun 349:987-994
    • (2006) Biochem. Biophys. Res. Commun. , vol.349 , pp. 987-994
    • Min, J.K.1    Kim, J.H.2    Cho, Y.L.3    Kwon, Y.G.4
  • 21
    • 17844410317 scopus 로고    scopus 로고
    • Microglial activation in chronic neurodegenerative diseases: Roles of apoptotic neurons and chronic stimulation
    • Minghetti L, Ajmone-Cat MA, De Berardinis MA, De Simone R (2005) Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation. Brain Res Rev 48:251-256
    • (2005) Brain Res. Rev. , vol.48 , pp. 251-256
    • Minghetti, L.1    Ajmone-Cat, M.A.2    De Berardinis, M.A.3    De Simone, R.4
  • 22
    • 0026697724 scopus 로고
    • NeuN, a neuronal specific nuclear protein in vertebrates
    • Mullen RJ, Buck CR, Smith AM (1992) NeuN, a neuronal specific nuclear protein in vertebrates. Development 116:201-211
    • (1992) Development , vol.116 , pp. 201-211
    • Mullen, R.J.1    Buck, C.R.2    Smith, A.M.3
  • 23
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • Narumiya S, Sugimoto Y, Ushikubi F (1999) Prostanoid receptors: structures, properties, and functions. Physiol Rev 79:1193-1226
    • (1999) Physiol. Rev. , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 24
    • 0028183354 scopus 로고
    • Malonylginsenoside Rb1 potentiates nerve growth factor (NGF)-induced neurite outgrowth of cultured chick embryonic dorsal root ganglia
    • Nishiyama N, Cho SI, Kitagama I, Saito H (1994) Malonylginsenoside Rb1 potentiates nerve growth factor (NGF)-induced neurite outgrowth of cultured chick embryonic dorsal root ganglia. Biol Pharm Bull 17:509-513
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 509-513
    • Nishiyama, N.1    Cho, S.I.2    Kitagama, I.3    Saito, H.4
  • 25
    • 21144444049 scopus 로고    scopus 로고
    • Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW 264.7 cells induced by lipopolysaccaride
    • Park EK, Shin YW, Lee HU, Kim SS, Lee YC (2005) Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW 264.7 cells induced by lipopolysaccaride. Biol Pharm Bull 28:652-656
    • (2005) Biol. Pharm. Bull. , vol.28 , pp. 652-656
    • Park, E.K.1    Shin, Y.W.2    Lee, H.U.3    Kim, S.S.4    Lee, Y.C.5
  • 26
    • 4344622460 scopus 로고    scopus 로고
    • Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate
    • Radad K, Gille G, Moldzio R, Saito H, Rausch WD (2004) Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate. Brain Res 1021:41-53
    • (2004) Brain Res. , vol.1021 , pp. 41-53
    • Radad, K.1    Gille, G.2    Moldzio, R.3    Saito, H.4    Rausch, W.D.5
  • 27
    • 33746326513 scopus 로고    scopus 로고
    • Rotenone induces cell death in primary dopaminergic culture by increase ROS production and inhibiting mitochondrial respiration
    • Radad K, Rausch WD, Gille G (2006) Rotenone induces cell death in primary dopaminergic culture by increase ROS production and inhibiting mitochondrial respiration. Neurochem Int 49:379-386
    • (2006) Neurochem. Int. , vol.49 , pp. 379-386
    • Radad, K.1    Rausch, W.D.2    Gille, G.3
  • 28
    • 33745269269 scopus 로고    scopus 로고
    • Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection
    • Ruano D, Revilla E, Gavilan MP, Vizuete ML (2006) Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection. Neuroscience 104:1157-1168
    • (2006) Neuroscience , vol.104 , pp. 1157-1168
    • Ruano, D.1    Revilla, E.2    Gavilan, M.P.3    Vizuete, M.L.4
  • 29
    • 0141655182 scopus 로고    scopus 로고
    • Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 and parthenolide (feverfew)
    • Smolinski AT, Pestka JJ (2003) Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 and parthenolide (feverfew). Food Chem Toxicol 41:1381-1390
    • (2003) Food Chem. Toxicol. , vol.41 , pp. 1381-1390
    • Smolinski, A.T.1    Pestka, J.J.2
  • 30
    • 33644504214 scopus 로고    scopus 로고
    • Prostaglandin E2 deteriorates N-methyl-D-aspartate receptor-mediated cytotoxicity possibly by activating EP2 receptors in cultured cortical neurons
    • Takadera T, Ohyashiki T (2006) Prostaglandin E2 deteriorates N-methyl-D-aspartate receptor-mediated cytotoxicity possibly by activating EP2 receptors in cultured cortical neurons. Life Sci 78:1878-1883
    • (2006) Life Sci. , vol.78 , pp. 1878-1883
    • Takadera, T.1    Ohyashiki, T.2
  • 31
    • 1342323332 scopus 로고    scopus 로고
    • Andrographolide reduces inflammationmediated dopaminergic neurodegeneration in mesencephalic neuronglia cultures by inhibiting microglial activation
    • Wang T, Liu B, Zhang W (2004) Andrographolide reduces inflammationmediated dopaminergic neurodegeneration in mesencephalic neuronglia cultures by inhibiting microglial activation. J Pharmacol Exp Ther 308:975-983
    • (2004) J. Pharmacol. Exp. Ther. , vol.308 , pp. 975-983
    • Wang, T.1    Liu, B.2    Zhang, W.3
  • 32
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of kB kinase-b
    • Yin MJ, Yamamoto Y, Gaynor RB (1998) The anti-inflammatory agents aspirin and salicylate inhibit the activity of kB kinase-b. Nature 396:77-80
    • (1998) Nature , vol.396 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 33
    • 1042304295 scopus 로고    scopus 로고
    • Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice
    • Yokozawa T, Satoh A, Cho EJ (2004) Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice. J Pharm Pharmacol 56:107-113
    • (2004) J. Pharm. Pharmacol. , vol.56 , pp. 107-113
    • Yokozawa, T.1    Satoh, A.2    Cho, E.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.