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Volumn 26, Issue 5, 2003, Pages 375-382

Effect of ginsenoside Rd on nitric oxide system induced by lipopolysaccharide plus TNF-α in C6 rat glioma cells

Author keywords

C6 glioma cell; ERK; Fra 1; Ginsenoside Rd; Jun B; Lipopolysaccharide; Nitric oxide; TNF

Indexed keywords


EID: 16344391360     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02976694     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P. and Karin, M., The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta, 1072, 129-157 (1991).
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 2
    • 0032032424 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures
    • Bhat, N. R., Zhang, P., Lee, J. C., and Hogan, E. L., Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures. J. Neurosci., 18, 1633-1641 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 1633-1641
    • Bhat, N.R.1    Zhang, P.2    Lee, J.C.3    Hogan, E.L.4
  • 3
    • 0027973242 scopus 로고
    • Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains
    • Bo, L., Dawson, T. M., Wesselingh, S., Mork, S., Choi, S., Kong, P. A., Hanley, D., and Trapp, B. D., Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann. Neurol., 36, 778-786 (1994).
    • (1994) Ann. Neurol. , vol.36 , pp. 778-786
    • Bo, L.1    Dawson, T.M.2    Wesselingh, S.3    Mork, S.4    Choi, S.5    Kong, P.A.6    Hanley, D.7    Trapp, B.D.8
  • 4
    • 0025191219 scopus 로고
    • Isolation of nitric oxide synthase, a calmodulin requiring enzyme
    • Bredt, D. S. and Snyder, S. H., Isolation of nitric oxide synthase, a calmodulin requiring enzyme. Proc. Natl. Acad. Sci. U.S.A., 87, 682-685 (1990).
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 682-685
    • Bredt, D.S.1    Snyder, S.H.2
  • 5
    • 0025296139 scopus 로고
    • Calcium-dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin
    • Busse, R. and Mulsch, A., Calcium-dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin. FEBS Lett., 265, 133-136 (1990).
    • (1990) FEBS Lett. , vol.265 , pp. 133-136
    • Busse, R.1    Mulsch, A.2
  • 6
    • 0035019373 scopus 로고    scopus 로고
    • IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38 (mapk) in a mouse macrophage cell line
    • Chan, E. D. and Riches, D. W., IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38 (mapk) in a mouse macrophage cell line. Am. J. Physiol. Cell Physiol., 280, C441-450 (2001).
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Chan, E.D.1    Riches, D.W.2
  • 7
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acidic guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. and Sacchi, N., Single-step method of RNA isolation by acidic guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 8
    • 0028360840 scopus 로고
    • Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice
    • Cross, A. H., Misko, T. P., Lin, R. F., Hickey, W. F., Trotter, J. L., and Tilton, R. G., Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice. J. Clin. Invest., 93, 2684-2690 (1994).
    • (1994) J. Clin. Invest. , vol.93 , pp. 2684-2690
    • Cross, A.H.1    Misko, T.P.2    Lin, R.F.3    Hickey, W.F.4    Trotter, J.L.5    Tilton, R.G.6
  • 10
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., Lebovitz, R. M., and Roeder, R. G., Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11, 1475-1489 (1983).
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 12
    • 0035678118 scopus 로고    scopus 로고
    • Stimulation of nitric oxide synthesis by the aqueous extract of Panax ginseng root in RAW 264.7 cells
    • Friedl, R., Moeslinger, T., Kopp, B., and Spieckermann, P. G., Stimulation of nitric oxide synthesis by the aqueous extract of Panax ginseng root in RAW 264.7 cells. Br. J. Pharmacol., 134, 1663-1670 (2001).
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1663-1670
    • Friedl, R.1    Moeslinger, T.2    Kopp, B.3    Spieckermann, P.G.4
  • 13
    • 0026486613 scopus 로고
    • Induction of calciumindependent nitric oxide synthase activity in primary rat glial cultures
    • Galea, E., Feinstein, D. L., and Reis, D. J., Induction of calciumindependent nitric oxide synthase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. U.S.A., 89, 10945-10949 (1992).
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 10945-10949
    • Galea, E.1    Feinstein, D.L.2    Reis, D.J.3
  • 14
    • 0028211176 scopus 로고
    • Cloning and expression of inducible nitric oxide synthase from rat astrocytes
    • Galea, E., Reis, D. J., and Feinstein, D. L., Cloning and expression of inducible nitric oxide synthase from rat astrocytes. J. Neurosci. Res., 37, 406-414 (1994).
    • (1994) J. Neurosci. Res. , vol.37 , pp. 406-414
    • Galea, E.1    Reis, D.J.2    Feinstein, D.L.3
  • 15
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signalling in the nervous system
    • Garthwaite, J., Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci., 14, 60-67 (1991).
    • (1991) Trends Neurosci. , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 16
    • 0030757369 scopus 로고    scopus 로고
    • Panax ginseng pharmacology: A nitric oxide link?
    • Gillis, C. N., Panax ginseng pharmacology: a nitric oxide link? Biochem. Pharmacol., 54, 1-8 (1997).
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 1-8
    • Gillis, C.N.1
  • 18
    • 0029460699 scopus 로고
    • Differential regulation by cytokines of human astrocyte nitric oxide production
    • Hu, S., Sheng, W. S., Peterson, P. K., and Chao, C. C., Differential regulation by cytokines of human astrocyte nitric oxide production. Glia, 15, 491-494 (1995).
    • (1995) Glia , vol.15 , pp. 491-494
    • Hu, S.1    Sheng, W.S.2    Peterson, P.K.3    Chao, C.C.4
  • 20
    • 0028899835 scopus 로고
    • Dietary ginsenosides improve endothelium-dependent relaxation in the thoracic aorta of hypercholesterolemic rabbit
    • Kang, S. Y., Kim, S. H., Schini, V. B., and Kim, N. D., Dietary ginsenosides improve endothelium-dependent relaxation in the thoracic aorta of hypercholesterolemic rabbit. Gen. Pharmacol., 26, 483-487 (1995).
    • (1995) Gen. Pharmacol. , vol.26 , pp. 483-487
    • Kang, S.Y.1    Kim, S.H.2    Schini, V.B.3    Kim, N.D.4
  • 21
    • 0031596324 scopus 로고    scopus 로고
    • Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration
    • Kim, Y. C., Kim, S. R., Markelonis, G. J., and Oh, T. H., Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration. J. Neurosci. Res., 53, 426-432 (1998).
    • (1998) J. Neurosci. Res. , vol.53 , pp. 426-432
    • Kim, Y.C.1    Kim, S.R.2    Markelonis, G.J.3    Oh, T.H.4
  • 23
    • 30444433994 scopus 로고    scopus 로고
    • Published erratum appears
    • [Published erratum appears in Proc. Natl. Acad. Sci. U.S.A. 90, 5378.]
    • Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 5378
  • 24
    • 0014949207 scopus 로고
    • Cleavage of structure proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U., Cleavage of structure proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.1
  • 25
    • 0037721104 scopus 로고    scopus 로고
    • The Regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide plus tumor necrosis factor-a in C6 cells; the involvements of AP-1 and NFκB
    • in press
    • Lee, J. K., Choi, S. S., Won, J. S., and Suh, H. W., The Regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide plus tumor necrosis factor-a in C6 cells; the involvements of AP-1 and NFκB. Life Sci., in press (2003).
    • (2003) Life Sci.
    • Lee, J.K.1    Choi, S.S.2    Won, J.S.3    Suh, H.W.4
  • 26
    • 0027440762 scopus 로고
    • Nitric oxide synthase: Function and mechanism
    • Marletta, M. A., Nitric oxide synthase: function and mechanism. Adv. Exp. Med. Biol., 338, 281-284 (1993).
    • (1993) Adv. Exp. Med. Biol. , vol.338 , pp. 281-284
    • Marletta, M.A.1
  • 27
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill, J. E., Ignarro, L. J., Sherman, M. P., Melinek, J., and Lane, T. E., Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol., 151, 2132-2141 (1993).
    • (1993) J. Immunol. , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 28
    • 0028061167 scopus 로고
    • Nitric oxide as a potential pathological mechanism in demyelination: Its differential effects on primary glial cells in vitro
    • Mitrovic, B., Ignarro, L. J., Montestruque, S., Smoll, A., and Merrill, J. E., Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro. Neuroscience, 61, 575-585 (1994).
    • (1994) Neuroscience , vol.61 , pp. 575-585
    • Mitrovic, B.1    Ignarro, L.J.2    Montestruque, S.3    Smoll, A.4    Merrill, J.E.5
  • 29
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C., Nitric oxide as a secretory product of mammalian cells. FASEB J., 6, 3051-3064 (1992).
    • (1992) FASEB J. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 30
    • 0031003699 scopus 로고    scopus 로고
    • Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes
    • Pahan, K., Namboodiri, A. M., Sheikh, F. G., Smith, B. T., and Singh, I., Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes. J. Biol. Chem., 272, 7786-7791 (1997b).
    • (1997) J. Biol. Chem. , vol.272 , pp. 7786-7791
    • Pahan, K.1    Namboodiri, A.M.2    Sheikh, F.G.3    Smith, B.T.4    Singh, I.5
  • 31
    • 0032579511 scopus 로고    scopus 로고
    • Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes
    • Pahan, K., Sheikh, F. G., Khan, M., Namboodiri, A. M., and Singh, I., Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. J. Biol. Chem., 273, 2591-2600 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 2591-2600
    • Pahan, K.1    Sheikh, F.G.2    Khan, M.3    Namboodiri, A.M.4    Singh, I.5
  • 32
    • 0031438501 scopus 로고    scopus 로고
    • Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages
    • Pahan, K., Sheikh, F. G., Namboodiri, A. M., and Singh, I., Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J. Clin. Invest., 100, 2671-2679 (1997a).
    • (1997) J. Clin. Invest. , vol.100 , pp. 2671-2679
    • Pahan, K.1    Sheikh, F.G.2    Namboodiri, A.M.3    Singh, I.4
  • 33
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endotheliumderived relaxing factor
    • Palmer, R. M., Ferrige, A. G., and Moncada, S., Nitric oxide release accounts for the biological activity of endotheliumderived relaxing factor. Nature, 327, 524-526 (1987).
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 34
    • 0029658691 scopus 로고    scopus 로고
    • Ginsenoside-Rh1 and Rh2 inhibit the induction of nitric oxide synthesis in murine peritoneal macrophages
    • Park, Y. C., Lee, C. H., Kang, H. S., Kim, K. W., Chung, H. T., and Kim, H. D., Ginsenoside-Rh1 and Rh2 inhibit the induction of nitric oxide synthesis in murine peritoneal macrophages. Biochem. Mol. Biol. Int., 40, 751-757 (1996).
    • (1996) Biochem. Mol. Biol. Int. , vol.40 , pp. 751-757
    • Park, Y.C.1    Lee, C.H.2    Kang, H.S.3    Kim, K.W.4    Chung, H.T.5    Kim, H.D.6
  • 35
    • 0023446425 scopus 로고
    • The anti-aggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide
    • Radomski, M. W., Palmer, R. M., and Moncada, S., The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br. J. Pharmacol., 92, 639-646 (1987).
    • (1987) Br. J. Pharmacol. , vol.92 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 36
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
    • Schreck, R., Rieber, P., and Baeuerle, P. A., Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J., 10, 2247-2258 (1991).
    • (1991) EMBO J. , vol.10 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 37
    • 0028464350 scopus 로고
    • Roles for protein kinases in the induction of nitric oxide synthase in astrocytes
    • Simmons, M. L. and Murphy, S., Roles for protein kinases in the induction of nitric oxide synthase in astrocytes. Glia, 11, 227-2234 (1994).
    • (1994) Glia , vol.11 , pp. 227-2234
    • Simmons, M.L.1    Murphy, S.2
  • 38
    • 0024959451 scopus 로고
    • Peptidyl-prolyl cistrans isomerase is the cyclosporin A-binding protein cyclophilin
    • Takahashi, N., Hayano, T., and Suzuki, M., Peptidyl-prolyl cistrans isomerase is the cyclosporin A-binding protein cyclophilin. Nature, 337, 473-475 (1989).
    • (1989) Nature , vol.337 , pp. 473-475
    • Takahashi, N.1    Hayano, T.2    Suzuki, M.3
  • 39
    • 0033838564 scopus 로고    scopus 로고
    • Ginsenoside-induced relaxation of human bronchial smooth muscle via release of nitric oxide
    • Tamaoki, J., Nakata, J., Kawatani, K., Tagaya, E., and Nagai, A., Ginsenoside-induced relaxation of human bronchial smooth muscle via release of nitric oxide. Br. J. Pharmacol., 130, 1859-1864 (2000).
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 1859-1864
    • Tamaoki, J.1    Nakata, J.2    Kawatani, K.3    Tagaya, E.4    Nagai, A.5
  • 40
    • 0028986193 scopus 로고
    • NF-kappa B: A lesson in family values
    • Thanos, D. and Maniatis, T., NF-kappa B: a lesson in family values. Cell, 80, 529-532 (1995).
    • (1995) Cell , vol.80 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 41
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T., and Gordon, J., Electrophoretic transfer of proteins from polyacrylamide gels to nitocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A., 76, 4350-4354 (1979).
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 42
    • 0032100679 scopus 로고    scopus 로고
    • Molecular cloning and analysis of the rat inducible nitric oxide synthase gene promoter in aortic smooth muscle cells
    • Zhang, H., Chen, X., Teng, X., Snead, C., and Catravas, J. D., Molecular cloning and analysis of the rat inducible nitric oxide synthase gene promoter in aortic smooth muscle cells. Biochem. Pharmacol., 55, 1873-1880 (1998).
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1873-1880
    • Zhang, H.1    Chen, X.2    Teng, X.3    Snead, C.4    Catravas, J.D.5


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