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Volumn 6, Issue 1, 2004, Pages 37-45

Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice

Author keywords

Aldehyde; Ebselen; Glutathione peroxidase; Heart; Iron; Oxygen free radical

Indexed keywords

ANTIOXIDANT; EBSELEN; FREE RADICAL; GLUTATHIONE PEROXIDASE; IRON; ORGANOSELENIUM DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRROLE DERIVATIVE; REACTIVE OXYGEN METABOLITE;

EID: 3843144067     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800403261350     Document Type: Article
Times cited : (33)

References (51)
  • 1
    • 0034232355 scopus 로고    scopus 로고
    • Iron-overload cardiomyopathy: Evidence for a free radical - Mediated mechanism of injury and dysfunction in a murine model
    • Bartfay WJ, Bartfay E. 2000a. Iron-overload cardiomyopathy: evidence for a free radical - mediated mechanism of injury and dysfunction in a murine model. Biol Res Nurs 2(1):49-59.
    • (2000) Biol Res Nurs , vol.2 , Issue.1 , pp. 49-59
    • Bartfay, W.J.1    Bartfay, E.2
  • 2
    • 0034547175 scopus 로고    scopus 로고
    • Systemic oxygen-free radical production in iron-loaded mice
    • Bartfay WJ, Bartfay E. 2000b. Systemic oxygen-free radical production in iron-loaded mice. Western J Nurs Res 22(8):927-35.
    • (2000) Western J Nurs Res , vol.22 , Issue.8 , pp. 927-935
    • Bartfay, W.J.1    Bartfay, E.2
  • 3
    • 0036513965 scopus 로고    scopus 로고
    • Decreasing effects of iron toxicosis on selenium and glutathione peroxidase activity
    • Bartfay WJ, Bartfay E. 2002. Decreasing effects of iron toxicosis on selenium and glutathione peroxidase activity. Western J Nurs Res 24(2):119-31.
    • (2002) Western J Nurs Res , vol.24 , Issue.2 , pp. 119-131
    • Bartfay, W.J.1    Bartfay, E.2
  • 4
    • 0032715141 scopus 로고    scopus 로고
    • A biochemical, histochemical, and electron microscopic study on the effects of iron-loading on the hearts of mice
    • Bartfay WJ, Butany J, Lehotay DC, Sole MJ, Hou D, Bartfay E, Liu PP. 1999. A biochemical, histochemical, and electron microscopic study on the effects of iron-loading on the hearts of mice. Cardiovasc Pathol 8(6):305-14.
    • (1999) Cardiovasc Pathol , vol.8 , Issue.6 , pp. 305-314
    • Bartfay, W.J.1    Butany, J.2    Lehotay, D.C.3    Sole, M.J.4    Hou, D.5    Bartfay, E.6    Liu, P.P.7
  • 5
    • 0142120134 scopus 로고    scopus 로고
    • Milk whey protein decreases oxygen free radical production in a murine model of chronic iron-overload cardiomyopathy
    • in press
    • Bartfay WJ, Davis MT, Medves JM, Lugowski S. 2003. Milk whey protein decreases oxygen free radical production in a murine model of chronic iron-overload cardiomyopathy. Can J Cardiol (in press).
    • (2003) Can J Cardiol
    • Bartfay, W.J.1    Davis, M.T.2    Medves, J.M.3    Lugowski, S.4
  • 9
    • 0037247905 scopus 로고    scopus 로고
    • Hemochromatosis. More common than you think
    • Borgaonkar MR. 2003. Hemochromatosis. More common than you think. Can Fam Phys 49:36-43.
    • (2003) Can Fam Phys , vol.49 , pp. 36-43
    • Borgaonkar, M.R.1
  • 10
    • 0031974301 scopus 로고    scopus 로고
    • Secondary iron-overload disorders
    • Bottomley SS. 1998. Secondary iron-overload disorders. Semin Hematol 35(1):77-86.
    • (1998) Semin Hematol , vol.35 , Issue.1 , pp. 77-86
    • Bottomley, S.S.1
  • 11
    • 0036194527 scopus 로고    scopus 로고
    • Hydrogen peroxide enhances iron-induced injury in isolated heart and ventricular cardiomyocyte in rats
    • Chen YY, Ho KP, Xia Q, Qian ZM. 2002. Hydrogen peroxide enhances iron-induced injury in isolated heart and ventricular cardiomyocyte in rats. Mol Cell Biochem 231(1-2):61-8.
    • (2002) Mol Cell Biochem , vol.231 , Issue.1-2 , pp. 61-68
    • Chen, Y.Y.1    Ho, K.P.2    Xia, Q.3    Qian, Z.M.4
  • 12
    • 0036527536 scopus 로고    scopus 로고
    • Amlodipine decreases iron uptake and oxygen free radical production in the heart of chronically iron overloaded mice
    • Crowe S, Bartfay WJ. 2002. Amlodipine decreases iron uptake and oxygen free radical production in the heart of chronically iron overloaded mice. Biol Res Nurs 3(4):189-97.
    • (2002) Biol Res Nurs , vol.3 , Issue.4 , pp. 189-197
    • Crowe, S.1    Bartfay, W.J.2
  • 14
    • 0037201941 scopus 로고    scopus 로고
    • Iron toxicity and antioxidant nutrients
    • Fraga C, Oteiza P. 2002. Iron toxicity and antioxidant nutrients. Toxicology 180(1):23.
    • (2002) Toxicology , vol.180 , Issue.1 , pp. 23
    • Fraga, C.1    Oteiza, P.2
  • 15
    • 0034022112 scopus 로고    scopus 로고
    • Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates
    • Handa Y, Kaneko M, Takeuchi H, Tsuchida A, Kobayashi H, Kubota T. 2000. Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates. Surg Neurol 53(4):323-9.
    • (2000) Surg Neurol , vol.53 , Issue.4 , pp. 323-329
    • Handa, Y.1    Kaneko, M.2    Takeuchi, H.3    Tsuchida, A.4    Kobayashi, H.5    Kubota, T.6
  • 18
    • 0033067885 scopus 로고    scopus 로고
    • Iron-mediated cardiovascular injury
    • Horwitz LD, Rosenthal EA. 1999. Iron-mediated cardiovascular injury. Vasc Med 4(2):93-9.
    • (1999) Vasc Med , vol.4 , Issue.2 , pp. 93-99
    • Horwitz, L.D.1    Rosenthal, E.A.2
  • 19
    • 0028608772 scopus 로고
    • Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction
    • Hoshida S, Kuzuya T, Nishida M, Yamashita N, Hori M, Kamada T, Tada M. 1994. Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction. Am J Physiol 267(6 Pt 2):H2342-7.
    • (1994) Am J Physiol , vol.267 , Issue.6 PART 2
    • Hoshida, S.1    Kuzuya, T.2    Nishida, M.3    Yamashita, N.4    Hori, M.5    Kamada, T.6    Tada, M.7
  • 20
    • 0034821411 scopus 로고    scopus 로고
    • Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia
    • Imai H, Masayasu H, Dewar D, Graham DI, Macrae IM. 2001. Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke 32(9):2149-54.
    • (2001) Stroke , vol.32 , Issue.9 , pp. 2149-2154
    • Imai, H.1    Masayasu, H.2    Dewar, D.3    Graham, D.I.4    Macrae, I.M.5
  • 22
    • 0035794020 scopus 로고    scopus 로고
    • Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80
    • Kobayashi T, Ohta Y, Yoshino J. 2001. Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80. Eur J Pharmacol 414(2-3):271-9.
    • (2001) Eur J Pharmacol , vol.414 , Issue.2-3 , pp. 271-279
    • Kobayashi, T.1    Ohta, Y.2    Yoshino, J.3
  • 23
    • 0345120142 scopus 로고    scopus 로고
    • Heart failure in beta-thalassemia
    • Kremastinos DT. 2001. Heart failure in beta-thalassemia. Congest Heart Fail 7(6):312-14.
    • (2001) Congest Heart Fail , vol.7 , Issue.6 , pp. 312-314
    • Kremastinos, D.T.1
  • 24
    • 0004866871 scopus 로고    scopus 로고
    • Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity
    • Lass A, Witting P, Stocker R, Esterbauer H. 1996. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: antioxidant actions in addition to hydroperoxide-reducing activity. Biochim Biophys Acta 1303(2):111-18.
    • (1996) Biochim Biophys Acta , vol.1303 , Issue.2 , pp. 111-118
    • Lass, A.1    Witting, P.2    Stocker, R.3    Esterbauer, H.4
  • 26
    • 0034075968 scopus 로고    scopus 로고
    • Ebselen protection against hydrogen peroxide-induced cytotoxicity and DNA damage in HL-60 cells
    • Li J, Chen JJ, Zhang F, Zhang C. 2000. Ebselen protection against hydrogen peroxide-induced cytotoxicity and DNA damage in HL-60 cells. Acta Pharmacol Sin 21(5):455-9.
    • (2000) Acta Pharmacol Sin , vol.21 , Issue.5 , pp. 455-459
    • Li, J.1    Chen, J.J.2    Zhang, F.3    Zhang, C.4
  • 28
    • 0033082143 scopus 로고    scopus 로고
    • Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: Mitochondrial function in cultured, iron-loaded heart cells
    • Link G, Konijn AM, Hershko C. 1999. Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: mitochondrial function in cultured, iron-loaded heart cells. J Lab Clin Med 133(2):179-88.
    • (1999) J Lab Clin Med , vol.133 , Issue.2 , pp. 179-188
    • Link, G.1    Konijn, A.M.2    Hershko, C.3
  • 29
    • 0031035450 scopus 로고    scopus 로고
    • The origin of the hydroxyl radical oxygen in the Fenton reaction
    • Lloyd RV, Hanna PM, Mason RP. 1997. The origin of the hydroxyl radical oxygen in the Fenton reaction. Free Radic Biol Med 22(5):885-8.
    • (1997) Free Radic Biol Med , vol.22 , Issue.5 , pp. 885-888
    • Lloyd, R.V.1    Hanna, P.M.2    Mason, R.P.3
  • 30
    • 0029021563 scopus 로고
    • Determination of aldehydes and other lipid peroxidation products in biological samples by gas chromatography-mass spectrometry
    • Luo XP, Yazdanpanah M, Bhooi N, Lehotay DC. 1995. Determination of aldehydes and other lipid peroxidation products in biological samples by gas chromatography-mass spectrometry. Ann Biochem 228(2):294-8.
    • (1995) Ann Biochem , vol.228 , Issue.2 , pp. 294-298
    • Luo, X.P.1    Yazdanpanah, M.2    Bhooi, N.3    Lehotay, D.C.4
  • 31
    • 0026636515 scopus 로고
    • Antioxidant effect of ebselen (PZ 51): Peroxidase mimetic activity on phospholipid and cholesterol hydroperoxides vs free radical scavenger activity
    • Maiorino M, Roveri A, Ursini F. 1992. Antioxidant effect of ebselen (PZ 51): peroxidase mimetic activity on phospholipid and cholesterol hydroperoxides vs free radical scavenger activity. Arch Biochem Biophys 295(2):404-9.
    • (1992) Arch Biochem Biophys , vol.295 , Issue.2 , pp. 404-409
    • Maiorino, M.1    Roveri, A.2    Ursini, F.3
  • 32
    • 0028559806 scopus 로고
    • Detection of oxygen-derived radicals in biological systems using electron spin resonance
    • Mason RP, Hanna PM, Burkitt MJ, Kadiiska MB. 1994. Detection of oxygen-derived radicals in biological systems using electron spin resonance. Environ Health Persp 102(suppl 10):33-6.
    • (1994) Environ Health Persp , vol.102 , Issue.10 SUPPL. , pp. 33-36
    • Mason, R.P.1    Hanna, P.M.2    Burkitt, M.J.3    Kadiiska, M.B.4
  • 33
    • 0032521138 scopus 로고    scopus 로고
    • Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis
    • Maulik N, Yoshida T, Das DK. 1998. Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis. Free Radic Biol Med 24(5):869-75.
    • (1998) Free Radic Biol Med , vol.24 , Issue.5 , pp. 869-875
    • Maulik, N.1    Yoshida, T.2    Das, D.K.3
  • 34
    • 0025058263 scopus 로고
    • Automated measurement of two indicators of human selenium status, and applicability to population studies
    • McMaster D, Bell N, Anderson P, Love AH. 1990. Automated measurement of two indicators of human selenium status, and applicability to population studies. Clin Chem 36(2):211-16.
    • (1990) Clin Chem , vol.36 , Issue.2 , pp. 211-216
    • McMaster, D.1    Bell, N.2    Anderson, P.3    Love, A.H.4
  • 35
    • 0033669158 scopus 로고    scopus 로고
    • The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease
    • Moussaoui S, Obinu MC, Daniel N, Reibaud M, Blanchard V, Imperato A. 2000. The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease. Exp Neurol 166(2):235-45.
    • (2000) Exp Neurol , vol.166 , Issue.2 , pp. 235-245
    • Moussaoui, S.1    Obinu, M.C.2    Daniel, N.3    Reibaud, M.4    Blanchard, V.5    Imperato, A.6
  • 36
    • 0032211555 scopus 로고    scopus 로고
    • Hydrogen peroxide induced impairment of post-ischemic ventricular function is prevented by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide)
    • Myers ML, Farhangkhoee P, Karmazyn M. 1998. Hydrogen peroxide induced impairment of post-ischemic ventricular function is prevented by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide). Cardiovasc Res 40(2):290-6.
    • (1998) Cardiovasc Res , vol.40 , Issue.2 , pp. 290-296
    • Myers, M.L.1    Farhangkhoee, P.2    Karmazyn, M.3
  • 37
    • 0034884323 scopus 로고    scopus 로고
    • Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice
    • Namura S, Nagata I, Takami S, Masayasu H, Kikuchi H. 2001. Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 32(8):1906-11.
    • (2001) Stroke , vol.32 , Issue.8 , pp. 1906-1911
    • Namura, S.1    Nagata, I.2    Takami, S.3    Masayasu, H.4    Kikuchi, H.5
  • 39
    • 0033042957 scopus 로고    scopus 로고
    • Ebselen in acute middle cerebral artery occlusion: A placebo-controlled, double-blind clinical trial
    • Ogawa A, Yoshimoto T, Kikuchi H, Sano K, Saito I, Yamaguchi T, Yasuhara H. 1999. Ebselen in acute middle cerebral artery occlusion: a placebo-controlled, double-blind clinical trial. Cerebrovasc Dis 9(2):112-18.
    • (1999) Cerebrovasc Dis , vol.9 , Issue.2 , pp. 112-118
    • Ogawa, A.1    Yoshimoto, T.2    Kikuchi, H.3    Sano, K.4    Saito, I.5    Yamaguchi, T.6    Yasuhara, H.7
  • 40
    • 0036946494 scopus 로고    scopus 로고
    • Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats
    • Ohta Y, Kobayashi T, Inui K, Yoshino J, Nakazawa S. 2002. Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats. Jap J Pharmacol 90(4):295-303.
    • (2002) Jap J Pharmacol , vol.90 , Issue.4 , pp. 295-303
    • Ohta, Y.1    Kobayashi, T.2    Inui, K.3    Yoshino, J.4    Nakazawa, S.5
  • 41
    • 0033536288 scopus 로고    scopus 로고
    • The beta-thalassemias
    • Olivieri NF. 1999. The beta-thalassemias. N Engl J Med 341(2):99-109.
    • (1999) N Engl J Med , vol.341 , Issue.2 , pp. 99-109
    • Olivieri, N.F.1
  • 43
    • 0036315867 scopus 로고    scopus 로고
    • Non-invasive cardiac assessment in beta-thalassaemia major
    • Ong ML, Hatle LK, Lai VM, Bosco J. 2002. Non-invasive cardiac assessment in beta-thalassaemia major. Int J Clin Pract 56(5):345-8.
    • (2002) Int J Clin Pract , vol.56 , Issue.5 , pp. 345-348
    • Ong, M.L.1    Hatle, L.K.2    Lai, V.M.3    Bosco, J.4
  • 44
    • 0037406739 scopus 로고    scopus 로고
    • Haemochromatosis
    • Pietrangelo A. 2003. Haemochromatosis. Gut 52(suppl 2):II23-30.
    • (2003) Gut , vol.52 , Issue.2 SUPPL.
    • Pietrangelo, A.1
  • 45
    • 0031886421 scopus 로고    scopus 로고
    • Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage
    • Saito I, Asano T, Sano K, Takakura K, Abe H, Yoshimoto T, Kikuchi H, Ohta T, Ishibashi S. 1998. Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. Neurosurgery 42(2):269-77.
    • (1998) Neurosurgery , vol.42 , Issue.2 , pp. 269-277
    • Saito, I.1    Asano, T.2    Sano, K.3    Takakura, K.4    Abe, H.5    Yoshimoto, T.6    Kikuchi, H.7    Ohta, T.8    Ishibashi, S.9
  • 46
    • 0034656845 scopus 로고    scopus 로고
    • Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics
    • Sies H, Arteel GE. 2000. Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics. Free Radic Biol Med 28(10):1451-5.
    • (2000) Free Radic Biol Med , vol.28 , Issue.10 , pp. 1451-1455
    • Sies, H.1    Arteel, G.E.2
  • 47
    • 0011869643 scopus 로고    scopus 로고
    • Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite
    • Sies H, Masumoto H. 1997. Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite. Adv Pharmacol 38:229-46.
    • (1997) Adv Pharmacol , vol.38 , pp. 229-246
    • Sies, H.1    Masumoto, H.2
  • 49
    • 0031963836 scopus 로고    scopus 로고
    • Ebselen in acute ischemic stroke: A placebo-controlled, double-blind clinical trial
    • Ebselen Study Group
    • Yamaguchi T, Sano K, Takakura K, Saito I, Shinohara Y, Asano T, Yasuhara H. 1998. Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke 29(1):12-17.
    • (1998) Stroke , vol.29 , Issue.1 , pp. 12-17
    • Yamaguchi, T.1    Sano, K.2    Takakura, K.3    Saito, I.4    Shinohara, Y.5    Asano, T.6    Yasuhara, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.