Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats

Japanese Journal of Pharmacology

Volumn 90, Issue 4, 2002, Pages 295-303

  Ohta, Yoshiji ^a   Kobayashi, Takashi ^b   Inui, Kazuo ^b   Yoshino, Junji ^b   Nakazawa, Saburo ^b  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

Compound 48 80; Ebselen; Gastric mucosal lesion (rat); Glutathione peroxidase; Neutrophil infiltration

Indexed keywords

COMPOUND 48-80; EBSELEN; GLUTATHIONE PEROXIDASE; HISTAMINE; MAST CELL DEGRANULATING PEPTIDE; MYELOPEROXIDASE; ORGANOSELENIUM DERIVATIVE; SEROTONIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; DISEASE COURSE; DISEASE SEVERITY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFECT; ENZYME ACTIVITY; HISTAMINE BLOOD LEVEL; MALE; MAST CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; RAT; SEROTONIN BLOOD LEVEL; STOMACH MUCOSA BLOOD FLOW; STOMACH MUCOSA LESION; STOMACH PROTECTION;

EID: 0036946494     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.90.295     Document Type: Article

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