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Volumn 196, Issue 2, 2008, Pages 523-531

Secretory products from human adipocytes impair endothelial function via nuclear factor κB

Author keywords

Adipocyte; Adipokine; Endothelial dysfunction; Fat; Obesity

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; VASCULAR CELL ADHESION MOLECULE 1;

EID: 38349108765     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.05.016     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 0348107406 scopus 로고    scopus 로고
    • Regulation of adipocytokines and insulin resistance
    • Fasshauer M., and Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia 46 (2003) 1594-1603
    • (2003) Diabetologia , vol.46 , pp. 1594-1603
    • Fasshauer, M.1    Paschke, R.2
  • 2
    • 0035581264 scopus 로고    scopus 로고
    • Usefulness of visceral obesity (waist/hip ratio) in predicting vascular endothelial function in healthy overweight adults
    • Brook R.D., Bard R.L., Rubenfire M., Ridker P.M., and Rajagopalan S. Usefulness of visceral obesity (waist/hip ratio) in predicting vascular endothelial function in healthy overweight adults. Am J Cardiol 88 (2001) 1264-1269
    • (2001) Am J Cardiol , vol.88 , pp. 1264-1269
    • Brook, R.D.1    Bard, R.L.2    Rubenfire, M.3    Ridker, P.M.4    Rajagopalan, S.5
  • 3
    • 33645472457 scopus 로고    scopus 로고
    • Effect of fat distribution on endothelial-dependent and endothelial-independent vasodilatation in healthy humans
    • Williams I.L., Chowienczyk P.J., Wheatcroft S.B., et al. Effect of fat distribution on endothelial-dependent and endothelial-independent vasodilatation in healthy humans. Diabetes Obes Metab 8 (2006) 296-301
    • (2006) Diabetes Obes Metab , vol.8 , pp. 296-301
    • Williams, I.L.1    Chowienczyk, P.J.2    Wheatcroft, S.B.3
  • 4
    • 13244259255 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction tested by blunted response to endothelium-dependent vasodilation by salbutamol and its related factors in uncomplicated pre-menopausal obese women
    • Suh H.S., Park Y.W., Kang J.H., et al. Vascular endothelial dysfunction tested by blunted response to endothelium-dependent vasodilation by salbutamol and its related factors in uncomplicated pre-menopausal obese women. Int J Obes (Lond) 29 (2005) 217-222
    • (2005) Int J Obes (Lond) , vol.29 , pp. 217-222
    • Suh, H.S.1    Park, Y.W.2    Kang, J.H.3
  • 5
    • 2342664831 scopus 로고    scopus 로고
    • Exercise training normalizes vascular dysfunction and improves central adiposity in obese adolescents
    • Watts K., Beye P., Siafarikas A., et al. Exercise training normalizes vascular dysfunction and improves central adiposity in obese adolescents. J Am Coll Cardiol 43 (2004) 1823-1827
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1823-1827
    • Watts, K.1    Beye, P.2    Siafarikas, A.3
  • 6
    • 12244254446 scopus 로고    scopus 로고
    • Effects of changes in body weight and insulin resistance on inflammation and endothelial function in morbid obesity after bariatric surgery
    • Vazquez L.A., Pazos F., Berrazueta J.R., et al. Effects of changes in body weight and insulin resistance on inflammation and endothelial function in morbid obesity after bariatric surgery. J Clin Endocrinol Metab 90 (2005) 316-322
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 316-322
    • Vazquez, L.A.1    Pazos, F.2    Berrazueta, J.R.3
  • 7
    • 0029744981 scopus 로고    scopus 로고
    • Role of nitric oxide, adenosine, and ATP-sensitive potassium channels in insulin-induced vasodilation
    • McKay M.K., and Hester R.L. Role of nitric oxide, adenosine, and ATP-sensitive potassium channels in insulin-induced vasodilation. Hypertension 28 (1996) 202-208
    • (1996) Hypertension , vol.28 , pp. 202-208
    • McKay, M.K.1    Hester, R.L.2
  • 8
    • 10044263319 scopus 로고    scopus 로고
    • Adiponectin, obesity, and cardiovascular disease
    • Fasshauer M., Paschke R., and Stumvoll M. Adiponectin, obesity, and cardiovascular disease. Biochimie 86 (2004) 779-784
    • (2004) Biochimie , vol.86 , pp. 779-784
    • Fasshauer, M.1    Paschke, R.2    Stumvoll, M.3
  • 9
    • 0038637251 scopus 로고    scopus 로고
    • Hypoadiponectinemia is closely linked to endothelial dysfunction in man
    • Shimabukuro M., Higa N., Asahi T., et al. Hypoadiponectinemia is closely linked to endothelial dysfunction in man. J Clin Endocrinol Metab 88 (2003) 3236-3240
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3236-3240
    • Shimabukuro, M.1    Higa, N.2    Asahi, T.3
  • 10
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi N., Kihara S., Arita Y., et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 103 (2001) 1057-1063
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 11
    • 0032587240 scopus 로고    scopus 로고
    • The role of TNFalpha and TNF receptors in obesity and insulin resistance
    • Hotamisligil G.S. The role of TNFalpha and TNF receptors in obesity and insulin resistance. J Intern Med 245 (1999) 621-625
    • (1999) J Intern Med , vol.245 , pp. 621-625
    • Hotamisligil, G.S.1
  • 12
    • 0141448772 scopus 로고    scopus 로고
    • Adipokines, inflammation, and the endothelium in diabetes
    • Aldhahi W., and Hamdy O. Adipokines, inflammation, and the endothelium in diabetes. Curr Diab Rep 3 (2003) 293-298
    • (2003) Curr Diab Rep , vol.3 , pp. 293-298
    • Aldhahi, W.1    Hamdy, O.2
  • 13
    • 0028010239 scopus 로고
    • Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation
    • Wang P., Ba Z.F., and Chaudry I.H. Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation. Am J Physiol 266 (1994) H2535-H2541
    • (1994) Am J Physiol , vol.266
    • Wang, P.1    Ba, Z.F.2    Chaudry, I.H.3
  • 14
    • 0030671491 scopus 로고    scopus 로고
    • Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo
    • Bhagat K., and Vallance P. Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. Circulation 96 (1997) 3042-3047
    • (1997) Circulation , vol.96 , pp. 3042-3047
    • Bhagat, K.1    Vallance, P.2
  • 15
    • 0347823193 scopus 로고    scopus 로고
    • Leptin promotes vascular remodeling and neointimal growth in mice
    • Schafer K., Halle M., Goeschen C., et al. Leptin promotes vascular remodeling and neointimal growth in mice. Arterioscler Thromb Vasc Biol 24 (2004) 112-117
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 112-117
    • Schafer, K.1    Halle, M.2    Goeschen, C.3
  • 16
    • 0037044397 scopus 로고    scopus 로고
    • Influence of leptin on arterial distensibility: a novel link between obesity and cardiovascular disease?
    • Singhal A., Farooqi I.S., Cole T.J., et al. Influence of leptin on arterial distensibility: a novel link between obesity and cardiovascular disease?. Circulation 106 (2002) 1919-1924
    • (2002) Circulation , vol.106 , pp. 1919-1924
    • Singhal, A.1    Farooqi, I.S.2    Cole, T.J.3
  • 17
    • 0347004641 scopus 로고    scopus 로고
    • Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions
    • Kawanami D., Maemura K., Takeda N., et al. Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions. Biochem Biophys Res Commun 314 (2004) 415-419
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 415-419
    • Kawanami, D.1    Maemura, K.2    Takeda, N.3
  • 18
    • 0043164953 scopus 로고    scopus 로고
    • Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction
    • Verma S., Li S.H., Wang C.H., et al. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation 108 (2003) 736-740
    • (2003) Circulation , vol.108 , pp. 736-740
    • Verma, S.1    Li, S.H.2    Wang, C.H.3
  • 19
    • 0035487109 scopus 로고    scopus 로고
    • Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans
    • Savage D.B., Sewter C.P., Klenk E.S., et al. Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans. Diabetes 50 (2001) 2199-2202
    • (2001) Diabetes , vol.50 , pp. 2199-2202
    • Savage, D.B.1    Sewter, C.P.2    Klenk, E.S.3
  • 20
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • Jaffe E.A., Nachman R.L., Becker C.G., and Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52 (1973) 2745-2756
    • (1973) J Clin Invest , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 21
    • 0036249956 scopus 로고    scopus 로고
    • A rapid, quantitative immunofunctional assay for measuring human leptin
    • Kratzsch J., Berthold A., Lammert A., et al. A rapid, quantitative immunofunctional assay for measuring human leptin. Horm Res 57 (2002) 127-132
    • (2002) Horm Res , vol.57 , pp. 127-132
    • Kratzsch, J.1    Berthold, A.2    Lammert, A.3
  • 22
    • 0027484675 scopus 로고
    • TNF in vascular pathology: the importance of platelet-endothelium interactions
    • Grau G.E., and Lou J. TNF in vascular pathology: the importance of platelet-endothelium interactions. Res Immunol 144 (1993) 355-363
    • (1993) Res Immunol , vol.144 , pp. 355-363
    • Grau, G.E.1    Lou, J.2
  • 23
    • 0028367655 scopus 로고
    • Effects of cytokines tumor necrosis factor alpha and interleukin 1 beta on endotoxin-mediated inhibition of endothelium-derived relaxing factor bioactivity and nitric oxide production in vascular endothelium
    • Myers P.R., Parker J.L., Tanner M.A., and Adams H.R. Effects of cytokines tumor necrosis factor alpha and interleukin 1 beta on endotoxin-mediated inhibition of endothelium-derived relaxing factor bioactivity and nitric oxide production in vascular endothelium. Shock 1 (1994) 73-78
    • (1994) Shock , vol.1 , pp. 73-78
    • Myers, P.R.1    Parker, J.L.2    Tanner, M.A.3    Adams, H.R.4
  • 24
    • 0033964671 scopus 로고    scopus 로고
    • Insulin-mediated stimulation of protein kinase Akt: a potent survival signaling cascade for endothelial cells
    • Hermann C., Assmus B., Urbich C., Zeiher A.M., and Dimmeler S. Insulin-mediated stimulation of protein kinase Akt: a potent survival signaling cascade for endothelial cells. Arterioscler Thromb Vasc Biol 20 (2000) 402-409
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 402-409
    • Hermann, C.1    Assmus, B.2    Urbich, C.3    Zeiher, A.M.4    Dimmeler, S.5
  • 25
    • 24644479276 scopus 로고    scopus 로고
    • The potential role of resistin in atherogenesis
    • Burnett M.S., Lee C.W., Kinnaird T.D., et al. The potential role of resistin in atherogenesis. Atherosclerosis 182 (2005) 241-248
    • (2005) Atherosclerosis , vol.182 , pp. 241-248
    • Burnett, M.S.1    Lee, C.W.2    Kinnaird, T.D.3
  • 26
    • 0037023656 scopus 로고    scopus 로고
    • Leptin induces endothelin-1 in endothelial cells in vitro
    • Quehenberger P., Exner M., Sunder-Plassmann R., et al. Leptin induces endothelin-1 in endothelial cells in vitro. Circ Res 90 (2002) 711-718
    • (2002) Circ Res , vol.90 , pp. 711-718
    • Quehenberger, P.1    Exner, M.2    Sunder-Plassmann, R.3
  • 27
    • 0032999682 scopus 로고    scopus 로고
    • Leptin induces oxidative stress in human endothelial cells
    • Bouloumie A., Marumo T., Lafontan M., and Busse R. Leptin induces oxidative stress in human endothelial cells. FASEB J 13 (1999) 1231-1238
    • (1999) FASEB J , vol.13 , pp. 1231-1238
    • Bouloumie, A.1    Marumo, T.2    Lafontan, M.3    Busse, R.4
  • 28
    • 0035973147 scopus 로고    scopus 로고
    • Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
    • Park H.Y., Kwon H.M., Lim H.J., et al. Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp Mol Med 33 (2001) 95-102
    • (2001) Exp Mol Med , vol.33 , pp. 95-102
    • Park, H.Y.1    Kwon, H.M.2    Lim, H.J.3
  • 29
    • 33644668189 scopus 로고    scopus 로고
    • Pathophysiological levels of the obesity related peptides resistin and ghrelin increase adhesion molecule expression on human vascular endothelial cells
    • Skilton M.R., Nakhla S., Sieveking D.P., Caterson I.D., and Celermajer D.S. Pathophysiological levels of the obesity related peptides resistin and ghrelin increase adhesion molecule expression on human vascular endothelial cells. Clin Exp Pharmacol Physiol 32 (2005) 839-844
    • (2005) Clin Exp Pharmacol Physiol , vol.32 , pp. 839-844
    • Skilton, M.R.1    Nakhla, S.2    Sieveking, D.P.3    Caterson, I.D.4    Celermajer, D.S.5
  • 30
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin
    • Ouchi N., Kihara S., Arita Y., et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100 (1999) 2473-2476
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 31
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N., Kihara S., Arita Y., et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 102 (2000) 1296-1301
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 32
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin stimulates production of nitric oxide in vascular endothelial cells
    • Chen H., Montagnani M., Funahashi T., Shimomura I., and Quon M.J. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 278 (2003) 45021-45026
    • (2003) J Biol Chem , vol.278 , pp. 45021-45026
    • Chen, H.1    Montagnani, M.2    Funahashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 33
    • 2942720979 scopus 로고    scopus 로고
    • Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin
    • Kobayashi H., Ouchi N., Kihara S., et al. Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circ Res 94 (2004) e27-e31
    • (2004) Circ Res , vol.94
    • Kobayashi, H.1    Ouchi, N.2    Kihara, S.3
  • 34
    • 0036006743 scopus 로고    scopus 로고
    • Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris
    • Wilson S.H., Best P.J., Edwards W.D., et al. Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris. Atherosclerosis 160 (2002) 147-153
    • (2002) Atherosclerosis , vol.160 , pp. 147-153
    • Wilson, S.H.1    Best, P.J.2    Edwards, W.D.3
  • 35
    • 0028170816 scopus 로고
    • Structure, regulation and function of NF-kappa B
    • Siebenlist U., Franzoso G., and Brown K. Structure, regulation and function of NF-kappa B. Annu Rev Cell Biol 10 (1994) 405-455
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 405-455
    • Siebenlist, U.1    Franzoso, G.2    Brown, K.3
  • 36
    • 0032410406 scopus 로고    scopus 로고
    • The role of adhesion molecules in atherosclerosis
    • Chia M.C. The role of adhesion molecules in atherosclerosis. Crit Rev Clin Lab Sci 35 (1998) 573-602
    • (1998) Crit Rev Clin Lab Sci , vol.35 , pp. 573-602
    • Chia, M.C.1
  • 37
    • 0842303207 scopus 로고    scopus 로고
    • Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome
    • Wang T.D., Chen W.J., Lin J.W., Chen M.F., and Lee Y.T. Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome. Am J Cardiol 93 (2004) 362-365
    • (2004) Am J Cardiol , vol.93 , pp. 362-365
    • Wang, T.D.1    Chen, W.J.2    Lin, J.W.3    Chen, M.F.4    Lee, Y.T.5
  • 38
    • 33644853793 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activation with pioglitazone improves endothelium-dependent dilation in nondiabetic patients with major cardiovascular risk factors
    • Campia U., Matuskey L.A., and Panza J.A. Peroxisome proliferator-activated receptor-gamma activation with pioglitazone improves endothelium-dependent dilation in nondiabetic patients with major cardiovascular risk factors. Circulation 113 (2006) 867-875
    • (2006) Circulation , vol.113 , pp. 867-875
    • Campia, U.1    Matuskey, L.A.2    Panza, J.A.3
  • 39
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (prospective pioglitazone clinical trial in macrovascular events): a randomised controlled trial
    • Dormandy J.A., Charbonnel B., Eckland D.J., et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (prospective pioglitazone clinical trial in macrovascular events): a randomised controlled trial. Lancet 366 (2005) 1279-1289
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.3
  • 40
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARgamma
    • Lehrke M., and Lazar M.A. The many faces of PPARgamma. Cell 123 (2005) 993-999
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 41
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu J.G., Javorschi S., Hevener A.L., et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51 (2002) 2968-2974
    • (2002) Diabetes , vol.51 , pp. 2968-2974
    • Yu, J.G.1    Javorschi, S.2    Hevener, A.L.3
  • 42
    • 0036930844 scopus 로고    scopus 로고
    • Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone
    • Motoshima H., Wu X., Sinha M.K., et al. Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone. J Clin Endocrinol Metab 87 (2002) 5662-5667
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5662-5667
    • Motoshima, H.1    Wu, X.2    Sinha, M.K.3
  • 43
    • 0036481709 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
    • Yang W.S., Jeng C.Y., Wu T.J., et al. Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 25 (2002) 376-380
    • (2002) Diabetes Care , vol.25 , pp. 376-380
    • Yang, W.S.1    Jeng, C.Y.2    Wu, T.J.3
  • 44
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization
    • Combs T.P., Wagner J.A., Berger J., et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 143 (2002) 998-1007
    • (2002) Endocrinology , vol.143 , pp. 998-1007
    • Combs, T.P.1    Wagner, J.A.2    Berger, J.3
  • 45
    • 15444347751 scopus 로고    scopus 로고
    • Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat
    • Hallakou S., Doare L., Foufelle F., et al. Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat. Diabetes 46 (1997) 1393-1399
    • (1997) Diabetes , vol.46 , pp. 1393-1399
    • Hallakou, S.1    Doare, L.2    Foufelle, F.3
  • 46
    • 15844415080 scopus 로고    scopus 로고
    • Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice
    • Zhang B., Graziano M.P., Doebber T.W., et al. Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice. J Biol Chem 271 (1996) 9455-9459
    • (1996) J Biol Chem , vol.271 , pp. 9455-9459
    • Zhang, B.1    Graziano, M.P.2    Doebber, T.W.3
  • 47
    • 0029894050 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes
    • Kallen C.B., and Lazar M.A. Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci USA 93 (1996) 5793-5796
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5793-5796
    • Kallen, C.B.1    Lazar, M.A.2
  • 48
    • 0000113890 scopus 로고    scopus 로고
    • Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma
    • de Vos P., Lefebvre A.M., Miller S.G., et al. Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma. J Clin Invest 98 (1996) 1004-1009
    • (1996) J Clin Invest , vol.98 , pp. 1004-1009
    • de Vos, P.1    Lefebvre, A.M.2    Miller, S.G.3
  • 49
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
    • Okuno A., Tamemoto H., Tobe K., et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest 101 (1998) 1354-1361
    • (1998) J Clin Invest , vol.101 , pp. 1354-1361
    • Okuno, A.1    Tamemoto, H.2    Tobe, K.3


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