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Volumn 113, Issue 6, 2006, Pages 867-875

Peroxisome proliferator-activated receptor-γ activation with pioglitazone improves endothelium-dependent dilation in nondiabetic patients with major cardiovascular risk factors

Author keywords

Atherosclerosis; Endothelium derived factors; Inflammation; Risk factors; Vasodilation

Indexed keywords

ACETYLCHOLINE; BRADYKININ; C REACTIVE PROTEIN; FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; NITROPRUSSIDE SODIUM; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PLACEBO; TRIACYLGLYCEROL; VASODILATOR AGENT; 2,4 THIAZOLIDINEDIONE DERIVATIVE;

EID: 33644853793     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.105.549618     Document Type: Article
Times cited : (112)

References (30)
  • 1
    • 0025334367 scopus 로고
    • Regulatory functions of the vascular endothelium
    • Vane JR, Änggård EE, Botting RM. Regulatory functions of the vascular endothelium. N Engl J Med. 1990;323:27-36.
    • (1990) N Engl J Med , vol.323 , pp. 27-36
    • Vane, J.R.1    Änggård, E.E.2    Botting, R.M.3
  • 2
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 3
    • 0028918698 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with essential hypertension: Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway
    • Panza JA, Garcia C, Kilcoyne CM, Quyyumi AA, Cannon RO. Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that nitric oxide abnormality is not localized to a single signal transduction pathway. Circulation. 1995;91:1732-1738.
    • (1995) Circulation , vol.91 , pp. 1732-1738
    • Panza, J.A.1    Garcia, C.2    Kilcoyne, C.M.3    Quyyumi, A.A.4    Cannon, R.O.5
  • 4
    • 0027445135 scopus 로고
    • The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients
    • Casino PR, Kilcoyne CM, Quyyumi AA, Hoeg JM, Panza JA. The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients. Circulation. 1993;88:2541-2547.
    • (1993) Circulation , vol.88 , pp. 2541-2547
    • Casino, P.R.1    Kilcoyne, C.M.2    Quyyumi, A.A.3    Hoeg, J.M.4    Panza, J.A.5
  • 7
    • 4944250523 scopus 로고    scopus 로고
    • Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes. Further evidence for the existence of the "vulnerable" patient
    • Fichtlscherer S, Breuer S, Zeiher AM. Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes. Further evidence for the existence of the "vulnerable" patient. Circulation. 2004;110:1926-1932.
    • (2004) Circulation , vol.110 , pp. 1926-1932
    • Fichtlscherer, S.1    Breuer, S.2    Zeiher, A.M.3
  • 8
    • 0033536224 scopus 로고    scopus 로고
    • Epidemiology of insulin resistance and its relation to coronary artery disease
    • Haffner SM. Epidemiology of insulin resistance and its relation to coronary artery disease. Am J Cardiol. 1999;84:11J-14J.
    • (1999) Am J Cardiol , vol.84
    • Haffner, S.M.1
  • 9
    • 0842277242 scopus 로고    scopus 로고
    • Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
    • Grundy SM, Brewer HB, Cleeman JI, Smith SC, Lenfant C. Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation. 2004;109:433-438.
    • (2004) Circulation , vol.109 , pp. 433-438
    • Grundy, S.M.1    Brewer, H.B.2    Cleeman, J.I.3    Smith, S.C.4    Lenfant, C.5
  • 10
    • 0347628963 scopus 로고    scopus 로고
    • Insulin impairs endothelium-dependent vasodilation independent of insulin sensitivity or lipid profile
    • Campia U, Sullivan G, Bryant MB, Waclawiw MA, Quon MJ, Panza JA. Insulin impairs endothelium-dependent vasodilation independent of insulin sensitivity or lipid profile. Am J Physiol. 2004;286:H76-H82.
    • (2004) Am J Physiol , vol.286
    • Campia, U.1    Sullivan, G.2    Bryant, M.B.3    Waclawiw, M.A.4    Quon, M.J.5    Panza, J.A.6
  • 11
    • 2442711384 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor and atherogenesis: Regulator of gene expression in vascular cells
    • Marx N, Duez H, Fruchart JC, Staels B. Peroxisome proliferator activated receptor and atherogenesis: regulator of gene expression in vascular cells. Circ Res. 2004;94:1168-1178.
    • (2004) Circ Res , vol.94 , pp. 1168-1178
    • Marx, N.1    Duez, H.2    Fruchart, J.C.3    Staels, B.4
  • 12
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Järvinen H. Thiazolidinediones. N Engl J Med. 2004;351:1106-1118.
    • (2004) N Engl J Med , vol.351 , pp. 1106-1118
    • Yki-Järvinen, H.1
  • 13
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
    • Lehman JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem. 1995;270:12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehman, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 14
    • 0842289940 scopus 로고    scopus 로고
    • In type 2 diabetes, rosiglitazone therapy for insulin resistance ameliorates endothelial dysfunction independent of glucose control
    • Pistrosch F, Passauer J, Fischer S, Fuecker K, Hanefeld M, Gross P. In type 2 diabetes, rosiglitazone therapy for insulin resistance ameliorates endothelial dysfunction independent of glucose control. Diabetes Care. 2004;27:484-490.
    • (2004) Diabetes Care , vol.27 , pp. 484-490
    • Pistrosch, F.1    Passauer, J.2    Fischer, S.3    Fuecker, K.4    Hanefeld, M.5    Gross, P.6
  • 15
    • 0034456568 scopus 로고    scopus 로고
    • Quantitative Insulin-sensitivity Check Index (QUICKI): A simple, accurate method for assessing insulin sensitivity in humans
    • Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative Insulin-sensitivity Check Index (QUICKI): a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85:2402-2410.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2402-2410
    • Katz, A.1    Nambi, S.S.2    Mather, K.3    Baron, A.D.4    Follmann, D.A.5    Sullivan, G.6    Quon, M.J.7
  • 16
    • 0026560294 scopus 로고
    • Blood pressure control by the renin-angiotensin system in normotensive subjects: Assessment by angiotensin converting enzyme and renin inhibition
    • Kiowski W, Linder L, Kleinbloesem C, van Brummelen P, Buhler FR. Blood pressure control by the renin-angiotensin system in normotensive subjects: assessment by angiotensin converting enzyme and renin inhibition. Circulation. 1992;85:1-8.
    • (1992) Circulation , vol.85 , pp. 1-8
    • Kiowski, W.1    Linder, L.2    Kleinbloesem, C.3    Van Brummelen, P.4    Buhler, F.R.5
  • 17
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle to acetylcholine
    • Furchgott RF, Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle to acetylcholine. Nature. 1980;288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadski, J.V.2
  • 18
    • 0017795243 scopus 로고
    • Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic-GMP formation in smooth muscles and platelets
    • Bohme E, Graf H, Schultz G. Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic-GMP formation in smooth muscles and platelets. Adv Cycl Nucl Res. 1978;9:131-143.
    • (1978) Adv Cycl Nucl Res , vol.9 , pp. 131-143
    • Bohme, E.1    Graf, H.2    Schultz, G.3
  • 20
    • 0027161713 scopus 로고
    • Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension
    • Panza JA, Casino PR, Kilcoyne CM, Quyyumi AA. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation. 1993;87:1468-1474.
    • (1993) Circulation , vol.87 , pp. 1468-1474
    • Panza, J.A.1    Casino, P.R.2    Kilcoyne, C.M.3    Quyyumi, A.A.4
  • 21
    • 0033520304 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
    • Delerive P, Martin-Nizard F, Chinetti G, Trottein F, Fruchart JC, Najib J, Duriez P, Staels B. Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res. 1999;85:394-402.
    • (1999) Circ Res , vol.85 , pp. 394-402
    • Delerive, P.1    Martin-Nizard, F.2    Chinetti, G.3    Trottein, F.4    Fruchart, J.C.5    Najib, J.6    Duriez, P.7    Staels, B.8
  • 22
    • 0037231474 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands increase release of nitric oxide from endothelial cells
    • Calnek DS, Mazzella L, Roser S, Roman J, Hart MC. Peroxisome proliferator-activated receptor γ ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol. 2003;23:52-57.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 52-57
    • Calnek, D.S.1    Mazzella, L.2    Roser, S.3    Roman, J.4    Hart, M.C.5
  • 23
    • 0034660182 scopus 로고    scopus 로고
    • PPARγ activators inhibit interferon-γ-induced expression of the T cell active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
    • Marx N, Mach F, Sauty A, Sarafi M, Libby P, Plutzky J, Luster AD. PPARγ activators inhibit interferon-γ-induced expression of the T cell active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J Immunol. 2000;164:6503-6508.
    • (2000) J Immunol , vol.164 , pp. 6503-6508
    • Marx, N.1    Mach, F.2    Sauty, A.3    Sarafi, M.4    Libby, P.5    Plutzky, J.6    Luster, A.D.7
  • 24
    • 0034633847 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells
    • Takeda K, Ichiki T, Tokunou T, Funakoshi Y, Iino N, Hirano K, Kanaide H, Takeshita A. Peroxisome proliferator-activated receptor activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells. Circulation. 2000;102:1834-1839.
    • (2000) Circulation , vol.102 , pp. 1834-1839
    • Takeda, K.1    Ichiki, T.2    Tokunou, T.3    Funakoshi, Y.4    Iino, N.5    Hirano, K.6    Kanaide, H.7    Takeshita, A.8
  • 25
    • 0344333464 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor γ activators inhibit gene expression and migration in human vascular smooth muscle cells
    • Marx N, Schönbeck U, Lazar MA, Libby P, Plutzky J. Peroxisome proliferator activated receptor γ activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res. 1998;83:1097-1103.
    • (1998) Circ Res , vol.83 , pp. 1097-1103
    • Marx, N.1    Schönbeck, U.2    Lazar, M.A.3    Libby, P.4    Plutzky, J.5
  • 26
    • 0033034381 scopus 로고    scopus 로고
    • Effects of troglitazone on frequency of coronary vasospastic-induced angina pectoris in patients with diabetes mellitus
    • Murakami T, Mizuno S, Ohsato K, Moriuchi I, Arai Y, Nio Y, Kaku B, Takahashi Y, Ohnaka M. Effects of troglitazone on frequency of coronary vasospastic-induced angina pectoris in patients with diabetes mellitus. Am J Cardiol. 1999;84:92-94.
    • (1999) Am J Cardiol , vol.84 , pp. 92-94
    • Murakami, T.1    Mizuno, S.2    Ohsato, K.3    Moriuchi, I.4    Arai, Y.5    Nio, Y.6    Kaku, B.7    Takahashi, Y.8    Ohnaka, M.9
  • 27
    • 0034730098 scopus 로고    scopus 로고
    • Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease
    • Fichtlscherer S, Rosenberger G, Walter DH, Breuer S, Dimmeler S, Zeiher AM. Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease. Circulation. 2000;102:1000-1006.
    • (2000) Circulation , vol.102 , pp. 1000-1006
    • Fichtlscherer, S.1    Rosenberger, G.2    Walter, D.H.3    Breuer, S.4    Dimmeler, S.5    Zeiher, A.M.6
  • 29
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptor at the crossroads between lipid metabolism and inflammation
    • Chinetti G, Fruchard J-C, Staels B. Peroxisome proliferator-activated receptors (PPARs): nuclear receptor at the crossroads between lipid metabolism and inflammation. Inflammation Res. 2000;49:497-505.
    • (2000) Inflammation Res , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchard, J.-C.2    Staels, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.