Non-synonymous polymorphisms in the human SLCO1B1 gene: An in vitro analysis of SNP c.1929A>C

Molecular Genetics and Genomics

Volumn 279, Issue 2, 2008, Pages 149-157

  Seithel, Annick ^a   Klein, Kathrin ^b   Zanger, Ulrich M ^b   Fromm, Martin F ^a   König, Jörg ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

Hepatic uptake; OATP1B1; Organic anion transporters; Pharmacogenetic; Polymorphism; Pravastatin; SLCO1B1 gene

Indexed keywords

AMINO ACID; BROMSULFOPHTHALEIN; ESTRADIOL 17 GLUCURONIDE; GENOMIC DNA; ORGANIC ANION TRANSPORTER; POLYCLONAL ANTIBODY; PRAVASTATIN; TAUROCHOLIC ACID; TRITIUM;

ADULT; AGED; ARTICLE; ASIAN; BLOOD SAMPLING; CAUCASIAN; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG DISPOSITION; DRUG TRANSPORT; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; ISOTOPE LABELING; LIVER RESECTION; LIVER TUMOR; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; OATP1B1 GENE; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RACE DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS; SLCO1B1 GENE;

AGED; BIOLOGICAL TRANSPORT; CELL LINE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; IMMUNOBLOTTING; LIVER; MALE; MIDDLE AGED; ORGANIC ANION TRANSPORTERS; POLYMORPHISM, SINGLE NUCLEOTIDE; PRAVASTATIN; SULFOBROMOPHTHALEIN; TAUROCHOLIC ACID; TRANSFECTION;

EID: 38349039581     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-007-0303-4     Document Type: Article

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