Localization of the Na+-D-glucose cotransporter SGLT1 in the blood-brain barrier

Histochemistry and Cell Biology

Volumn 121, Issue 3, 2004, Pages 201-207

  Elfeber, Katrin ^a   Köhler, Alwin ^a   Lutzenburg, Michael ^b   Osswald, Christina ^a   Galla, Hans Joachim ^c   Witte, Otto W ^b   Koepsell, Hermann ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Blood brain barrier; Brain ischemia; SGLT1; Sodium D glucose cotransporter; Sugar transport

Indexed keywords

COTRANSPORTER; GLUCOSE TRANSPORTER; MESSENGER RNA; SODIUM GLUCOSE COTRANSPORTER; SODIUM GLUCOSE COTRANSPORTER 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CAPILLARY ENDOTHELIUM; CELL MEMBRANE; CELL VACUOLE; CONTROLLED STUDY; GLUCOSE TRANSPORT; HEMISPHERE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REPERFUSION; SWINE; WESTERN BLOTTING;

ANIMALS; BLOOD-BRAIN BARRIER; CELLS, CULTURED; ENDOTHELIAL CELLS; GLUCOSE; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE GLYCOPROTEINS; MONOSACCHARIDE TRANSPORT PROTEINS; RATS; RATS, WISTAR; SODIUM-GLUCOSE TRANSPORTER 1; SWINE; UP-REGULATION;

RATTUS NORVEGICUS; SUS SCROFA;

EID: 1842737553     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-004-0633-9     Document Type: Article

References (30)

1. Bedersen JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17:472-476
2. +-glucose cotransporter. J Cell Biochem 84:115-131
3. 11C-methyl-D-glucoside, a tracer of the sodium-dependent glucose transporters. J Nucl Med 44:1075-1081
4. +-D-glucose cotransporter in muscle capillaries increases glucose permeability. Biochim Biophys Res Commun 314:301-305
5. Farrell CL, Pardridge WM (1991) Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary endothelial lumenal and ablumenal membranes: an electron microscopic immunogold study. Proc Natl Acad Sci U S A 88:5779-5783
6. 18F-fluoroalkyl-β-D-glucosides and their evaluation as tracers for sodium-dependent glucose transporters. J Nucl Med 44:1973-1981
7. Harik SI, Behmand RA, LaManna JC (1994) Hypoxia increases glucose transport at blood-brain barrier in rats. J Appl Physiol 77:896-901
8. Hawkins RA, Mans AM, Davis WD, Hibbard LS, Lu DM (1983) Glucose availability to individual cerebral structures is correlated to glucose metabolism. J Neurochem 40:1013-1018
9. Hediger MA, Rhoads DB (1994) Molecular physiology of sodium-glucose cotransporters. Physiol Rev 74:993-1026
10. +/glucose cotransporter. Biochim Biophys Acta 1103:37-44
11. Karnovsky MJ (1967) The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. J Cell Biol 35:213-236
12. Kipp H, Khoursandi S, Scharlau D, Kinne RKH (2003) More than apical: distribution of SGLT1 in Caco-2 cells. Am J Physiol Cell Physiol 285:C737-C749
13. 1 cells. J Biol Chem 276:45330-45340
14. Kyhse-Andersen J (1984) Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J Biochem Biophys Methods 10:203-209
15. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
16. +/glucose cotransporter. Re-evaluation of function and distribution of expression. J Biol Chem 269:12032-12039
17. Longa LZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91
18. Maher F, Vannucci SJ, Simpson IA (1994) Glucose transporter proteins in brain. FASEB J 8:1003-1011
19. Morgan DJ (1996) Permeability of myocardial capillaries to hydrophilic drugs: the paracellular pathway. Clin Exp Pharmacol Physiol 23:975-979
20. +/glucose transport in bovine brain artery endothelial cells. Stroke 29:844-849
21. Nishizaki T, Kammesheidt A, Sumikawa K, Asada T, Okada Y (1995) A sodium- and energy-dependent glucose transporter with similarities to SGLT1-2 is expressed in bovine cortical vessels. Neurosci Res 22:13-22
22. 1 cells: effects of D-glucose and monosaccharides. Mol Cell Biol 10:6491-6499
23. +-D-glucose cotransporter SGLT1 in neurons. J Neurochem 69:84-94
24. 18F] fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man. Circ Res 44:127-137
25. +/glucose cotransporter (SGLT1). FEBS Lett 469:98-100
26. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897-916
27. +-dependent glucose transporter in rat jejunum. Cell Tissue Res 267:3-9
28. +-dependent D-glucose symporters (SGLT1) in the ovine enterocyte and the parotid acinar cells. Biochem J 312:293-300
29. Tewes B, Franke H, Hellwig S, Hoheisel D, Decker S, Griesche D, Tilling T, Wegener J, Galla H-J (1997) Preparation of endothelial cells in primary cultures obtained from the brains of 6-month-old pigs. In: Boer AG de, Sutano W (eds) Drug transport across the blood-brain barrier (BBB): in vivo and in vitro techniques. Harwood Academic, Amsterdam, pp 91-97
30. Thorens B (1993) Facilitated glucose transporters in epithelial cells. Annu Rev Physiol 55:591-608