Expression of SDF-1-CXCR4 axis and an anti-remodelling effectiveness of foetal-liver stem cell transplantation in the infarcted rat heart

Journal of Physiology and Pharmacology

Volumn 58, Issue 4, 2007, Pages 729-744

  Czarnowska, E ^a   Gajerska Dzieciatkowska M ^b   Kusmierski K ^c   Lichomski, J ^c   Machaj, E K ^d   Pojda, Z ^d   Brudek, M ^a   Berȩsewicz, Andrzej ^b  

^a CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

^c INSTITUTE OF CARDIOLOGY   (Poland)

^d INSTITUTE OF ONCOLOGY   (Poland)

Author keywords

Capillary growth; Cardiomyocyte hypertrophy; Collagen accumulation; CXCR4; Foetal liver stem cells; Myocardial infarction; Rat; SDF 1; Remodelling; Stem cells; stem cells transplantation

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; COLLAGEN; GREEN FLUORESCENT PROTEIN; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DOWN REGULATION; DRUG INHIBITION; HEART INFARCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IMMUNOHISTOCHEMISTRY; LIVER TRANSPLANTATION; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; STEM CELL TRANSPLANTATION;

ANIMALS; CHEMOKINE CXCL12; FETAL STEM CELLS; LIVER; MYOCARDIAL INFARCTION; MYOCARDIUM; RATS; RATS, WISTAR; RECEPTORS, CXCR4; TIME FACTORS; VENTRICULAR REMODELING;

EID: 38149059817     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Nadal-Ginard B, Kajstura J, Leri A, Anversa P. Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ Res 2003; 92: 139-150.
2. Schachinger V, Assmus B, Britten MB et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial. J Am Coll Cardiol 2004; 44: 1690-1699.
3. Lee MS, Makkar RR. Stem-cell transplantation in myocardial infarction: a status report. Ann Intern Med 2004; 140: 729-737.
4. Muller P, Beltrami AP, Cesselli D, Pfeiffer P, Kazakov A, Bohm M. Myocardial regeneration by endogenous adult progenitor cells. J Mol Cell Cardiol 2005; 39: 377-387.
5. Vandervelde S, van Luyn MJ, Tio RA, Harmsen MC. Signaling factors in stem cell-mediated repair of infarcted myocardium. J Mol Cell Cardiol 2005; 39: 363-376.
6. Kucia M, Ratajczak MZ. Stem cells as a two edged sword - from regeneration to tumor formation. J Physiol Pharmacol 2006; 57 (Suppl 7): 5-16.
7. Bel A, Messas E, Agbulut O et al. Transplantation of autologous fresh bone marrow into infarcted myocardium: a word of caution. Circulation 2003; 108 (Suppl II): II247-II252.
8. Kucia M, Dawn B, Hunt G et al. Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction. Circ Res 2004; 95: 1191-1199.
9. Ceradini DJ, Kulkarni AR, Callaghan MJ et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004; 10: 858-864.
10. Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005; 106: 1901-1910.
11. Ratajczak MZ, Reca R, Wysoczynski M, Yan J, Ratajczak J. Modulation of the SDF-1-CXCR4 axis by the third complement component (C3) - implications for trafficking of CXCR4+ stem cells. Exp Hematol 2006; 34: 986-995.
12. Kollet O, Shivtiel S, Chen YQ et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. J Clin Invest 2003; 112: 160-169.
13. Askari AT, Unzek S, Popovic ZB et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet 2003; 362: 697-703.
14. Abbott JD, Huang Y, Liu D, Hickey R, Krause DS, Giordano FJ. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 2004; 110: 3300-3305.
15. Shintani S, Murohara T, Ikeda H et al. Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 2001; 103: 2776-2779.
16. Wojakowski W, Tendera M, Michalowska A et al. Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction. Circulation 2004; 110: 3213-3220.
17. Sandri M, Adams V, Gielen S et al. Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: results of 3 randomized studies. Circulation 2005; 111: 3391-3399.
18. Adams V, Lenk K, Linke A et al. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler Thromb Vasc Biol 2004; 24: 684-690.
19. Damas JK, Waehre T, Yndestad A et al. Stromal cell-derived factor-1 alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects. Circulation 2002; 106: 36-42.
20. Machaj EK, Grabowska I, Gajkowska A et al. Differentiation potential of the fetal rat liver-derived cells. Folia Histochem Cytobiol 2005; 43: 217-222.
21. Pillarisetti K, Gupta SK. Cloning and relative expression analysis of rat stromal cell derived factor-1 (SDF-1): SDF-1 alpha mRNA is selectively induced in rat model of myocardial infarction. Inflammation 2001; 25: 293-300.
22. Yamaguchi J, Kusano KF, Masuo O et al. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation 2003; 107: 1322-1328.
23. Hiasa K, Ishibashi M, Ohtani K et al. Gene transfer of stromal cell-derived factor-1 alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway - Next-generation chemokine therapy for therapeutic neovascularization. Circulation 2004; 109: 2454-2461.
24. Masuda H, Asahara T. Post-natal endothelial progenitor cells for neovascularization in tissue regeneration. Cardiovasc Res 2003; 58: 390-398.
25. Aiuti A, Webb IJ, Bleul C, Springer T, Gutierrez-Ramos JC. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 1997; 185: 111-120.
26. Mohle R, Bautz F, Rafii S, Moore MA, Brugger W, Kanz L. The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 1998; 91: 4523-4530.
27. Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 1996; 184: 1101-1109.
28. Gupta SK, Pillarisetti K, Lysko PG. Modulation of CXCR4 expression and SDF-lalpha functional activity during differentiation of human monocytes and macrophages. J Leukoc Biol 1999; 66: 135-143.
29. Gupta SK, Lysko PG, Pillarisetti K, Ohlstein E, Stadel JM. Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines. J Biol Chem 1998; 273: 4282-4287.
30. Pyo RT, Sui J, Dhume A et al. CXCR4 modulates contractility in adult cardiac myocytes. J Mol Cell Cardiol 2006; 41: 834-844.
31. Segret A, Rucker-Martin C, Pavoine C et al. Structural localization and expression of CXCL12 and CXCR4 in rat heart and isolated cardiac myocytes. J Histochem Cytochem 2007; 55: 141-150.
32. Damas JK, Eiken HG, Oie E et al. Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure. Cardiovasc Res 2000; 47: 778-787.
33. Durand C, Dzierzak E. Embryonic beginnings of adult hematopoietic stem cells. Haematologica 2005; 90: 100-108.
34. Dan YY, Riehle KJ, Lazaro C et al. Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proc Natl Acad Sci U S A 2006; 103: 9912-9917.
35. Olivetti G, Capasso JM, Meggs LG, Sonnenblick EH, Anversa P. Cellular basis of chronic ventricular remodeling after myocardial infarction in rats. Circ Res 1991; 68: 856-869.
36. Anversa P, Beghi C, Kikkawa Y, Olivetti G. Myocardial infarction in rats. Infarct size, myocyte hypertrophy, and capillary growth. Circ Res 1986; 58: 26-37.
37. Kocher AA, Schuster MD, Szabolcs MJ et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001; 7: 430-436.
38. Schuster MD, Kocher AA, Seki T et al Myocardial neovascularization by bone marrow angioblasts results in cardiomyocyte regeneration. Am J Physiol 2004; 287: H525-H532.
39. Cleutjens JP, Verluyten MJ, Smiths JF, Daemen MJ. Collagen remodeling after myocardial infarction in the rat heart. Am J Pathol 1995; 147: 325-338.
40. Lutgens E, Daemen MJ, de Muinck ED, Debets J, Leenders P, Smits JF. Chronic myocardial infarction in the mouse: cardiac structural and functional changes. Cardiovasc Res 1999; 41: 586-593.
41. Orlic D, Kajstura J, Chimenti S et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705.
42. Murry CE, Soonpaa MH, Reinecke H et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 2004; 428: 664-668.
43. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 2004; 428: 668-673.
44. Nygren JM, Jovinge S, Breitbach M et al. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med 2004; 10: 494-501.
45. Heidemann J, Ogawa H, Rafiee P et al. Mucosal angiogenesis regulation by CXCR4 and its ligand CXCL12 expressed by human intestinal microvascular endothelial cells. Am J Physiol 2004; 286: G1059-G1068.
46. Mirshahi F, Pourtau J, Li H et al. SDF-1 activity on microvascular endothelial cells: consequences on angiogenesis in in vitro and in vivo models. Thromb Res 2000; 99: 587-594.
47. Ii M, Nishimura H, Iwakura A et al. Endothelial progenitor cells are rapidly recruited to myocardium and mediate protective effect of ischemic preconditioning via "imported" nitric oxide synthase activity. Circulation 2005; 111: 1114-1120.