Modulation of CXCR4 expression and SDF-1α functional activity during differentiation of human monocytes and macrophages

Journal of Leukocyte Biology

Volumn 66, Issue 1, 1999, Pages 135-143

  Gupta, Shalley K ^a   Pillarisetti, Kodandaram ^a   Lysko, Paul G ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Atherosclerosis; HL 60 cells; Intracellular calcium

Indexed keywords

CALCIUM ION; CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LOW DENSITY LIPOPROTEIN; MESSENGER RNA;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL FUNCTION; CELL ISOLATION; CELL MIGRATION; FOAM CELL; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA ANALYSIS; RNA DEGRADATION; TRANSCRIPTION REGULATION;

EID: 0032994867     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.66.1.135     Document Type: Article

References (38)

1. Edgington, S. M. (1993) Chemokines in cardiovascular disease. Do chemoattractant cytokines regulate the progression of atherosclerosis? Biotechnol. 11, 676-681.
2. Nelken, N. A., Coughlin, S. R., Gordon, D., Wilcox, J. N. (1991) Monocyte chemoattractant protein-1 in human atheromatous plaques. J. Clin. Invest. 88, 1121-1127.
3. Wang, N., Tabas, I., Winchester, R., Ravalli, S., Rabbani, L. E., Tall, A. (1996) Interleukin 8 is induced by cholesterol loading of macrophages and expressed by macrophage foam cells in human atheroma. J. Biol. Chem. 271, 8837-8842.
4. Taub, D. D., Oppenheim, J. J. (1994) Chemokines, inflammation and the immune system. Ther. Immunol. 1, 229-246.
5. Stoeckle, M. Y., Barker, K. A. (1990) Two burgeoning families of platelet factor 4-related proteins: Mediators of the inflammatory response. New Biol. 2, 313-323.
6. Kelner, G. S., Kennedy, J., Bacon, K. B., Kleyensteuber, S., Largaespada, D. A., Jenkins, N. A., Copeland, N. G., Bazan, J. F., Moore, K. W., Schall, T. J., Zlotnik, A. (1994) Lymphotactin: a cytokine that represents a new class of chemokine. Science 266, 1395-1399.
7. Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A., Schall, T. J. (1997) A new class of membrane-bound chemokine with a CX3C motif. Nature 385, 640-644.
8. Rollins, B. J. (1997) Chemokines. Blood 90, 909-928.
9. Oberlin, E., Amara, A., Bachelerie, F., Bessia, C., Virelizier, J-L., Arenzana-Seisdedos, F., Schwartz, O., Heard, J-L., Clark-Lewis, I., Legler, D. F., Loetscher, M., Baggiolini, M., Moser, B. (1996) The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell line-adapted HIV-1. Nature 382, 833-835.
10. Feng, Y., Broder, C. C., Kennedy, P. E., Berger, E. A. (1996) HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272, 872-877.
11. Bleul, C. C., Fuhlbrigge, R. C., Casanovas, J. M., Aiuti, A., Springer, T. A. (1996) A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J. Exp. Med. 184, 1101-1109.
12. Nomura, H., Nielsen, B. W., Matsushima, K. (1993) Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors. Int. Immunol. 5, 1239-1249.
13. Loetscher, M., Geiser, T., O'Reilly, T., Zwahlen, R., Baggiolini, M., Moser, B. (1994) Cloning of a human seven-transmembrane receptor, LESTR, that is highly expressed in leukocytes. J. Biol. Chem. 269, 232-237.
14. Hori, T., Sakaida, H., Sato, A., Nakajima, T., Shida, H., Yoshie, O., Uchiyama, T. (1998) Detection and delineation of CXCR-4 (fusin) as an entry and fusion cofactor for T cell-tropic HIV-1 by three different monoclonal antibodies. J. Immunol. 160, 180-188.
15. Nagasawa, T., Kikutani, H., Kishimoto, T. (1994) Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl. Acad. Sci. USA 91, 2305-2309.
16. Shirozu. M., Nakano, T., Inazawa, J., Tashiro, K., Tada, H., Shinohara, T., Honjo, T. (1995) Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF 1) gene. Genomics 28, 495-500.
17. Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S., Kitamura, Y., Yoshida, N., Kikutani, H., Kishimoto, T. (1996) Defects of B-cell lymphopoiesis and hone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382, 635-638.
18. Tachibana, K., Hirota, S., Iizasa, H., Yoshida, H., Kawabata, K., Kataoka, Y., Kitamura, Y., Matsushima, K., Yoshida, N., Nishikawa, S., Kishimoto, T., Nagasawa, T. (1998) The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393, 591-594.
19. Zou, Y-R., Kottman, A. H., Kuroda, M., Taniuchi, I., Littman, D. R. (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393, 595-599.
20. Gupta, S. K., Lysko, P. G., Pillarisetti, K., Ohlstein, E., Stadel, J. M. (1998) Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines. J. Biol. Chem. 273, 4282-4287.
21. Volin, M. V., Joseph, L., Shockley, M. S., Davies, P. F. (1998) Chemokine receptor CXCR4 expression in endothelium. Biochem. Biophys. Res. Commun. 242, 46-53.
22. Ross, R. (1992) Inflammation: Basic Principles and Clinical Correlates, 2nd ed. (J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds.) New York: Raven Press.
23. Birchall, A. M., Bishop, J., Bradshaw, D., Cline, A., Coffey, J., Elliott, L. H., Gibson, V. M., Greenham, A., Hallam, T. J., Harris, W., Hill, C. H., Hutchings, A., Lament, A. G., Lawton, G., Lewis, E. J., Maw, A., Nixon, J. S., Pole, D., Wadsworth, J., Wilkinson, S. E. (1994) Ro 32-0432, a selective and orally active inhibitor of protein kinase C prevents T-cell activation. J. Pharmacol. Exp. Ther. 268, 922-929.
24. Colotta, F., Peri, G., Villa, A., Mantovani, A. (1984) Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells. I. Effectors belong to the monocyte-macrophage lineage. J. Immunol. 132, 936-944.
25. Collins, S. J. (1987) The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood 70, 1233-1244.
26. Marzio, P. D., Tse, J., Landau, N. R. (1997) Chemokine receptor regulation and HIV type 1 tropism in monocyte-macrophages. AIDS Res. Human Retroviruses 14, 129-138.
27. Ross, R. (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809.
28. Homma, Y., Genimell, M. A., Huberman, E. (1988) Protein kinase C activities with different characteristics, including substrate specificity, from two human HL-60 leukemia cell variants. Cancer Res. 48, 2744-2748.
29. Signoret, N., Oldridge, J., Pelchen-Matthews, A., Klasse, P. J., Tran, T., Brass, L. F., Rosenkilde, M. M., Schwartz, T. W., Holmes, W., Dallas, W., Luther, M. A., Wells, T. N. C., Hoxie, J. A.. Marsh, M. (1997) Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. J. Cell Biol. 139, 651-664.
30. Haribabu, B., Richardson, R. M., Fisher, I., Sozzani, S., Peiper, S. C., Horuk, R., Ali, H., Snyderman, R. (1997) Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization. J. Biol. Chem. 272, 28726-28731.
31. 4 in humans. Am. Rev. Respir. Dis. 131, 368-372.
32. Metcalf, D. (1991) Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. Science 254, 529-533.
33. Koren, H. S., Anderson, S. J., Larrick, J. W. (1979) In vitro activation of a human macrophage-like cell line. Nature 279, 328-331.
34. Tsuchiya, S., Yamabe, M., Yamaguchi, Y., Kobayashi, Y., Konno, T., Tada, K. (1980) Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int. J. Cancer 26, 171-176.
35. Forster, R., Kremer, E., Schubel, A., Breitfeld, D., Kleinschmidt, A., Nerl, C., Bernhardt, G., Lipp, M. (1998) Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. J. Immunol. 160, 1522-1531.
36. Schols, D., Struyf, S., Damme, J. V., Este, J. A., Henson, G., Clercq, E. D. (1997) Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J. Exp. Med. 186, 1383-1388.
37. Murukami, T., Nakajima, T., Koyanagi, Y., Tachibana, K., Fujii, N., Tamamura, H., Yoshida, N., Waki, M., Matsumoto, A., Yoshie, O., Kishimoto, T., Yamamoto, N., Nagasawa, T. (1997) A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection. J. Exp. Med. 186, 1389-1395.
38. Doranz, B. J., Grovit-Ferbas, K., Sharron, M. P., Mao, S-H., Goetz, M. D., Daar, E. S., Doms, R. W., O'Brien, W. A. (1997) A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J. Exp. Med. 186, 1395-1400.