Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: Molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer

Journal of Computer-Aided Molecular Design

Volumn 20, Issue 7-8, 2006, Pages 495-509

  Lynch, Diane L ^a   Reggio, Patricia H ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

Author keywords

Anandamide; Bilayer; Cannabinoid; CB1; Endocannabinoid; GPCR; Groove; Lipid; Molecular dynamics

Indexed keywords

HYDROGEN BONDS; LIPID BILAYERS; PHOSPHOLIPIDS;

ANANDAMIDE; BI-LAYER; CANNABINOIDS; DYNAMICS SIMULATION; ENDOCANNABINOID; GPCR; GROOVE; MODELLING SYSTEMS; PHOSPHOLIPIDS BILAYER; TRANSMEMBRANE HELIX;

MOLECULAR DYNAMICS;

ANANDAMIDE; BRANCHED CHAIN AMINO ACID; CANNABINOID 1 RECEPTOR; DIOLEOYLPHOSPHATIDYLCHOLINE; ENDOCANNABINOID; HYDROGEN; MEMBRANE PROTEIN; PHOSPHOLIPID;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HYDROGEN BOND; HYPOTHESIS; LIPID BILAYER; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SIMULATION;

EID: 37849186561     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-006-9068-9     Document Type: Article

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