Rhodopsin photointermediates in two-dimensional crystals at physiological temperatures

Biochemistry

Volumn 45, Issue 15, 2006, Pages 4974-4982

  Szundi, Istvan ^a   Ruprecht, Jonathan J ^b   Epps, Jacqueline ^a   Villa, Claudio ^b   Swartz, Trevor E ^a   Lewis, James W ^a   Schertler, Gebhard F X ^b   Kliger, David S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION; BIOLOGICAL MEMBRANES; CRYSTALLINE MATERIALS; DECAY (ORGANIC); PHYSIOLOGY; POLARIZATION;

RHODOPSIN CRYSTAL SUSPENSIONS; RHODOPSIN MEMBRANE; TIME-RESOLVED ABSORBANCE;

ENZYMES;

G PROTEIN COUPLED RECEPTOR; RHODOPSIN; SCHIFF BASE;

ARTICLE; BLEACHING; CRYSTAL; CRYSTAL STRUCTURE; KINETICS; LASER; LIGHT ABSORPTION; LINEAR DICHROISM; MEMBRANE; METABOLITE; PH; PHOTOCHEMICAL QUENCHING; PHOTOREACTIVITY; PHOTOSTIMULATION; PHYSIOLOGIC TEMPERATURE; PRIORITY JOURNAL; PROTON TRANSPORT; REACTIVE INTERMEDIATE; RECEPTOR UPREGULATION; TEMPERATURE; TWO DIMENSIONAL CRYSTAL;

ANIMALS; CATTLE; CRYSTALLIZATION; KINETICS; RHODOPSIN; SPECTROPHOTOMETRY; TEMPERATURE;

BOVINAE;

EID: 33645897322     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0524619     Document Type: Article

References (32)

1. Kliger, D. S., and Lewis, J. W. (1995) Spectral and kinetic characterization of visual pigment photointermediates, Isr. J. Chem. 35, 289-307.
2. Vilardaga, J.-P., Bünemann, M., Krasel, C., Castro, M., and Lohse, M. J. (2003) Measurement of the millisecond activation switch of G protein-coupled receptors in living cells, Nat. Biotechnol. 21, 807-812.
3. Kobilka, B. (2004) Agonist binding: A multistep process, Mol. Pharmacol. 65, 1060-1062.
4. Hoffmann, C., Gaietta, G., Bunemann, M., Adams, S. R., Oberdorff-Maass, S., Behr, B., Vilardaga, J. P., Tsien, R. Y., Eisman, M. H., and Lohse, M. J. (2005) A F1AsH-based FRET approach to determine G protein-coupled receptor activation in living cells, Nat. Methods 2, 171-176.
5. Okada, T., Sugihara, M., Bondar, A. N., Elstner, M., Entel, P., and Buss, V. (2004) The retinal conformation and its environment in rhodopsin in light of a new 2.2 angstrom crystal structure, J. Mol. Biol. 342, 571-583.
6. Li, J., Edwards, P. C., Burghammer, M., Villa, C., and Schertler, G. F. X. (2004) Structure of bovine rhodopsin in a trigonal crystal form, J. Mol. Biol. 343, 1409-1438.
7. Lewis, J. W., and Kliger, D. S. (2000) Absorption spectroscopy in studies of visual pigments: Spectral and kinetic characterization of intermediates, Methods Enzymol. 315, 164-178.
8. Ruprecht, J. J., Mielke, T., Vogel, R., Villa, C., and Schertler, G. F. X. (2004) Electron crystallography reveals the structure of metarhodopsin I, EMBO J. 23, 3609-3620.
9. Beck, M., Sakmar, T. P., and Siebert, F. (1998) Spectroscopic evidence for interaction between transmembrane helices 3, 4 and 5 in rhodopsin, Biochemistry 37, 7360-7639.
10. Vogel, R., Fan, G. B., Siebert, F., and Sheves, M. (2001) Anions stabilize a metarhodopsin II-like photoproduct with a protonated Schiff base, Biochemistry 40, 13342-13352.
11. Vogel, R., Ruprecht, J., Villa, C., Mielke, T., Schertler, G. F. X., and Siebert, F. (2004) Rhodopsin photoproducts in 2D crystals, J. Mol. Biol. 338, 597-609.
12. 1 crystal from bovine rhodopsin, J. Mol. Biol. 282, 991-1003.
13. Mielke, T., Villa, C., Edwards, P. C., Schertler. G. F. X., and Heyn, M. P. (2002) X-ray diffraction of heavy-atom labelled two-dimensional crystals of rhodopsin identifies the position of cysteine 140 in helix 3 and cysteine 316 in helix 8, J. Mol. Biol. 316, 693-709.
14. Lewis, J. W., and Kliger, D. S. (1991) Rotational diffusion effects on absorbency measurements-limitations to the magic-angle approach, Photochem. Photobiol. 54, 963-968.
15. Hug, S. J., Lewis, J. W., Einterz, C. M., Thorgeirsson, T. E., and Kliger, D. S. (1990) Nanosecond photolysis of rhodopsin: evidence for a new, blue-shifted intermediate, Biochemistry 29, 1475-1485.
16. Szundi, I., Lewis, J. W., and Kliger, D. S. (1997) Deriving reaction mechanisms from kinetic spectroscopy. Application to late rhodopsin intermediates, Biophys. J. 73, 688-702.
17. Albeck, A., Friedman, N., Ottolenghi, M., Sheves, M., Einterz, C. M., Hug, S. J., Lewis, J. W., and Kliger, D. S. (1988) Photolysis intermediates of the artificial visual pigment cis-5,6-dihydroisorhodopsin, Biophys. J. 55, 233-241.
18. Thorgeirsson, T. E., Lewis, J. W., Wallace-Williams, S. E., and Kliger, D. S. (1993) Effects of temperature on photointermediates from lumirhodopsin to metarhodopsin II, Biochemistry 32, 13861-13872.
19. Matthews, R. G., Hubbard, R., Brown, P. K., and Wald, G. (1963) Tautomeric forms of metarhodopsin, J. Gen. Physiol. 47, 215-240.
20. Jäger, S., Szundi, I., Lewis, J. W., Mah, T. L., and Kliger, D. S. (1998) Effects of pH on rhodopsin photointermediates from lumirhodopsin to metarhodopsin II, Biochemistry 37, 6998-7005.
21. Emrich, H. E., and Reich, R. (1974) Primary reactions of the visual process-Thermodynamic and kinetic influence of pH on the metarhodopsin I-II transition-Proton consumption as an effect of a conformational change, Z. Naturforsch., Teil C 29, 577-591.
22. Amis, S., Fahmy, K., Hofmann, K.-P., and Sakmar, T. P. (1994) A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin, J. Biol. Chem. 269, 23879-23881.
23. Szundi, I., Mah, T. L., Lewis, J. W., Jäger, S., Ernst, O. P., Hofmann, K. P., and Kliger, D. S. (1998) Proton-transfer reactions linked to rhodopsin activation, Biochemistry 37, 14237-14244.
24. Szundi, I., Lewis, J. W., van Kuijk, F. J. G. M., and Kliger, D. S. (2000) Effect of NADPH on formation and decay of human metarhodopsin III at physiological temperatures, Vision Res. 40, 3039-3048.
25. O'Brien, D. F., Costa, L. F., and Ott, R. A. (1977) Photochemical functionality of rhodopsin-phospholipid recombinant membranes, Biochemistry 16, 1295-1303.
26. Baldwin, P. A., and Hubbell, W. L. (1985) Effects of lipid environment on the light-induced conformational-changes of rhodopsin. 1. Absence of metarhodopsin-II production in dimyristoylphosphatidylcholine recombinant membranes, Biochemistry 24, 2624-2632.
27. Baldwin, P. A., and Hubbell, W. L. (1985) Effects of lipid environment on the light-induced conformational-changes of rhodopsin. 2. Roles of lipid chain-length, unsaturation, and phase state, Biochemistry 24, 2633-2639.
28. Schleicher, A., Franke, R., Hofmann, K. P., Finkelmann, H., and Weite, W. (1987) Deoxylysolecithin and a new bipheny detergent as solubilizing agents for bovine rhodopsin. Functional test by formation of metarhodopsin II and binding of G-protein, Biochemistry 26, 5908-5916.
29. Szundi, I., Lewis, J. W., and Kliger, D. S. (2005) Effect of digitonin on the Meta I-Meta II equilibrium, Photochem. Photobiol. 81, 866-873.
30. Mitchell, D. C., Straume, M., and Litman, B. J. (1992) Role of sn-1-saturated,sn-2-polyunsaturated phospholipids in control of membrane receptor conformational equilibrium: effects of cholesterol and acyl chain unsaturation on the metarhodopsin I ⇌ metarhodopsin II equilibrium, Biochemistry 31, 662-670.
31. Niu, S.-L., Mitchell, D. C., and Litman, B. J. (2002) Manipulation of cholesterol levels in rod disk membranes by methyl-β-cyclodextrin, J. Biol. Chem. 277, 20139-20145.
32. Lamola, A. A., Yamane, T., and Zipp, A. (1974) Effects of detergents and high pressure upon the metarhodopsin I ⇌ metarhodopsin II equilibrium, Biochemistry 13, 738-745.