Analysis of plasma serotonin levels and hemodynamic responses following chronic serotonin infusion in broilers challenged with bacterial lipopolysaccharide and microparticles

Poultry Science

Volumn 87, Issue 1, 2008, Pages 116-124

  Chapman, M E ^a   Taylor, R L ^b   Wideman Jr , R F ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

^b UNIVERSITY OF NEW HAMPSHIRE   (United States)

Author keywords

Broiler; Hypertension; Lipopolysaccharide; Microparticle; Serotonin

Indexed keywords

BACTERIA (MICROORGANISMS);

EID: 37849047465     PISSN: 00325791     EISSN: 15253171     Source Type: Journal    
DOI: 10.3382/ps.2007-00160     Document Type: Article

References (55)

1. Abenhaim, L., Y. Moride, F. Brenot, S. Rich, J. Benichou, X. Kurz, T. Higenbottam, C. Oakley, E. Wouters, M. Aubier, G. Simonneau, and B. Begaud. 1996. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N. Engl. J. Med. 335:609-616.
2. Ball, H. A., J. R. Parratt, and I. J. Zeitlin. 1983. Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anesthetized cats. Br. J. Clin. Pharmacol. 15:127-131.
3. Boe, J., B. Simonsson, and E. Stahl. 1980. Effect of histamine, 5-hydroxytryptamine and prostaglandins on isolated pulmonary arteries. Eur. J. Respir. Dis. 61:12-19.
4. Bowen, O. T., G. F. Erf, N. B. Anthony, and R. F. Wideman. 2006. Pulmonary hypertension triggered by lipopolysaccharide in ascites-susceptible and -resistant broilers is not amplified by aminoguanidine, a specific inhibitor of inducible nitric oxide synthase. Poult. Sci. 85:528-536.
5. Brigham, K. L., and B. Meyrick. 1986. Endotoxin and lung injury. Am. Rev. Respir. Dis. 133:913-927.
6. Chapman, M. E., and R. F. Wideman. 2001. Pulmonary wedge pressures confirm pulmonary hypertension in broilers is initiated by an excessive pulmonary arterial (precapillary) resistance. Poult. Sci. 80:468-473.
7. Chapman, M. E., and R. F. Wideman. 2002. Hemodynamic responses of broiler pulmonary vasculature to intravenously infused serotonin. Poult. Sci. 81:231-238.
8. Chapman, M. E., and R. F. Wideman. 2006a. Evaluation of the serotonin receptor blockers ketanserin and methiothepin on the pulmonary hypertensive responses of broilers to intravenously infused serotonin. Poult. Sci. 85:777-786.
9. Chapman, M. E., and R. F. Wideman. 2006b. Evaluation of the serotonin receptor blocker methiothepin in broilers injected intravenously with lipopolysaccharide and microparticles. Poult. Sci. 85:2222-2230.
10. Choi, D. S., and L. Maroteaux. 1996. Immunohistochemical localisation of the serotonin 5-HT2B receptor in mouse gut, cardiovascular system, and brain. FEBS Lett. 391:45-51.
11. Cox, C. P. 1985. Activation of washed chicken thrombocytes by 1-0-hexadecyl/octadecyl-2-acetyl-sn-glycero-3- phosphorylcholine (platelet activating factor). Comp. Biochem. Physiol. 82:145-151.
12. Douglas, J. G., J. F. Munro, A. H. Kitchin, A. L. Muir, and A. T. Proudfoot. 1981. Pulmonary hypertension and fenfluramine. Br. Med. J. 283:881-883.
13. Eddahibi, S., V. Fabre, C. Boni, M. P. Martres, B. Raffestin, M. Harmon, and S. Adnot. 1999. Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells - Relationship with the mitogenic action of serotonin. Circ. Res. 84:329-336.
14. Eddahibi, S., B. Raffestin, I. Pham, J. M. Launay, P. Aegerter, M. Sitbon, and S. Adnot. 1997. Treatment with 5-HT potentiates development of pulmonary hypertension in chronically hypoxic rats. Am. J. Physiol. 272:H1173-H1181.
15. Fanburg, B. L., and S. L. Lee. 1997. A new role for an old molecule: Serotonin as a mitogen. Am. J. Physiol. 272:L795-L806.
16. Ghosh, S., R. D. Latimer, B. M. Gray, R. J. Harwood, and A. Oduro. 1993. Endotoxin-induced organ injury. Crit. Care Med. 21:19-24.
17. Gobbi, G., P. Mirandola, P. L. Tazzari, F. Ricci, L. Caimi, A. Cacchioli, S. Papa, R. Conte, and M. Vitale. 2003. Flow cytometry detection of serotonin content and release in resting and activated platelets. Br. J. Haematol. 121:892-896.
18. Gonzalez, A.-M., A. P. L. Smith, C. J. Emery, and T. W. Higenbottam. 1998. The pulmonary hypertensive fawn-hooded rat has a normal serotonin transporter coding sequence. Am. J. Respir. Cell Mol. Biol. 19:245-249.
19. Hahn, A. W., T. J. Resink, T. Scott-Burden, J. Powell, Y. Dohi, and F. R. Buhler. 1990. Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: A novel autocrine function. Cell Regul. 1:649-659.
20. Hervé, P., J. M. Launay, M. L. Scrobohaci, F. Brenot, G. Simonneau, P. Petitpretz, P. Poubeau, J. Cerrina, P. Duroux, and L. Drouet. 1995. Increased plasma serotonin in primary pulmonary hypertension. Am. J. Med. 99:249-254.
21. Humbert, M., N. W. Morrell, S. L. Archer, K. R. Stenmark, M. R. MacLean, I. M. Lang, B. W. Christman, E. K. Weir, O. Eickelberg, N. F. Voelkel, and M. Rabinovitch. 2004. Cellular and molecular pathobiology of pulmonary arterial hypertension. J. Am. Coll. Cardiol. 43:13-24.
22. Jandel Scientific. 1994. SigmaStat Statistical Software User's Manual. Jandel Scientific Software, San Rafael, CA.
23. Julian, R. J. 1993. Ascites in poultry. Avian Pathol. 22:419-454.
24. Keegan, A., I. Morecroft, D. Smillie, M. N. Hicks, and M. R. MacLean. 2001. Contribution of the 5-HT(1B) receptor to hypoxia-induced pulmonary hypertension: Converging evidence using 5-HT(1B)-receptor knockout mice and the 5-HT(1B/1D)-receptor antagonist GR127935. Circ. Res. 89:1231-1239.
25. Kubo, K., and T. Kobayashi. 1985. Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. Am. Rev. Respir. Dis. 132:494-499.
26. Lacoste-Eleaume, A. S., C. Bleux, P. Quere, F. Coudert, C. Corbel, and C. Kanellopoulos-Langevin. 1994. Biochemical and functional characterization of an avian homolog of the integrin GPIIb-IIIa present on chicken thrombocytes. Exp. Cell Res. 213:198-209.
27. Lee, S. L., W. W. Wang, J. J. Lanzillo, and B. L. Fanburg. 1994. Serotonin produces both hyperplasia and hypertrophy of bovine pulmonary artery smooth muscle cells in culture. Am. J. Physiol. 266:146-152.
28. Lee, S. L., W. W. Wang, B. J. Moore, and B. L. Fanburg. 1991. Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture. Circ. Res. 68:1362-1368.
29. MacLean, M. R., G. Sweeney, M. Baird, K. M. McCulloch, M. Houslay, and I. Morecroft. 1996. 5-Hydroxytryptamine receptors mediating vasoconstriction in pulmonary arteries from control and pulmonary hypertensive rats. Br. J. Pharmacol. 119:917-930.
30. McCorkle, F. M., and R. L. Taylor. 1989. Continuous administration of 5-hydroxytryptamine alters cellular immunity in chickens. Comp. Biochem. Physiol. 94:511-514.
31. Meyer, D. C., and P. D. Sturkie. 1974. Distribution of serotonin among blood cells of the domestic fowl. Proc. Soc. Exp. Biol. Med. 147:382-386.
32. Meyrick, B. O., U. S. Ryan, and K. L. Brigham. 1986. Direct effects of E. coli endotoxin on structure and permeability of pulmonary endothelial monolayers and the endothelial layer of intimal explants. Am. J. Pathol. 1221:140-151.
33. Moro, M. A., V. M. Darley-Usmar, I. Lizasoain, Y. Su, R. G. Knowles, M. W. Rodomski, and S. Moncoda. 1995. The formation of nitric oxide donors from peroxynitrite. Br. J. Pharmacol. 116:1999-2004.
34. Nagaoka, T., M. Muramatsu, K. Sato, I. McMurtry, M. Oka, and Y. Fukuchi. 2001. Mild hypoxia causes severe pulmonary hypertension in fawn-hooded but not tester Moriyama rats. Respir. Physiol. 127:53-60.
35. Nemecek, G. M., S. R. Coughlin, D. A. Handley, and M. A. Moskowitz G. 1986. Stimulation of aortic smooth muscle cell mitogenesis by serotonin. Proc. Natl. Acad. Sci. USA 83:674-678.
36. Peacock, A. J., C. Picket, K. Morris, and J. T. Reeves. 1989. The relationship between rapid growth and pulmonary hemodynamics in the fast-growing broiler chicken. Am. Rev. Respir. Dis. 139:1524-1530.
37. Ramamoorthy, S., A. L. Bauman, K. R. Moore, H. Han, T. Yang-Feng, A. S. Chang, V. Ganapathy, and R. D. Blakely. 1993. Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization. Proc. Natl. Acad. Sci. USA 90:2542-2546.
38. Snapper, J. R., A. A. Hutchinson, M. L. Ogletree, and K. L. Brigham. 1983. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. J. Clin. Invest. 72:63-76.
39. Tschopp, T. B., and M. B. Zucker. 1972. Hereditary defect in platelet function in rats. Blood 40:217-226.
40. Tyler, R. C., M. Muramatsu, S. H. Abman, T. J. Selzner, D. M. Rodman, K. D. Bloch, and I. F. McMurtry. 1999. Variable expression of endothelial NO synthase in three forms of rat pulmonary hypertension. Am. J. Physiol. 276:L297-L303.
41. Wang, W., R. F. Wideman Jr., T. K. Bersi, and G. F. Erf. 2003. Pulmonary and hematological inflammatory responses to intravenous cellulose micro-particles in broilers. Poult. Sci. 82:771-780.
42. Wang, W., R. F. Wideman, and G. F. Erf. 2002a. Pulmonary hypertensive response to endotoxin in cellulose-primed and unprimed broiler chickens. Poult. Sci. 81:1224-1230.
43. Wideman, R. F. 2000. Cardio-pulmonary hemodynamics and ascites in broiler chickens. Poult. Avian Biol. Rev. 11:1-23.
44. Wideman, R. F. 2001. Pathophysiology of heart/lung disorders: Pulmonary hypertension syndrome in broiler chickens. World's Poult. Sci. J. 57:289-307.
45. Wideman, R. F., and G. F. Erf. 2002. Intravenous micro-particle injection and pulmonary hypertension in broiler chickens: Cardio-pulmonary hemodynamic responses. Poult. Sci. 81:877-886.
46. Wideman, R. F., and W. G. Bottje. 1993. Current understanding of the ascites syndrome and future research directions. Pages 1-20 in Nutr. Tech. Symp. Proc. Novus Int. Inc., St. Louis, MO.
47. Wideman, R. F., O. T. Bowen, G. F. Erf, and M. E. Chapman. 2006. Influence of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on the pulmonary hypertensive response to microparticle injections in broilers. Poult. Sci. 85:511-527.
48. Wideman, R. F., M. E. Chapman, W. Wang, and G. F. Erf. 2004. Immune modulation of the pulmonary hypertensive response to bacterial lipopolysaccharide (endotoxin) in broilers. Poult. Sci. 83:624-637.
49. Wideman, R. F., G. F. Erf, and M. E. Chapman. 2001. Intravenous endotoxin triggers pulmonary vasoconstriction and pulmonary hypertension in broiler chickens. Poult. Sci. 80:647-655.
50. Wideman, R. F., G. F. Erf, and M. E. Chapman. 2005b. N[omega]- nitro-L-arginine methyl ester (L-NAME) amplifies the pulmonary hypertensive response to microparticle injections in broilers. Poult. Sci. 84:1077-1091.
51. Wideman, R. F., G. F. Erf, M. E. Chapman, W. Wang, N. B. Anthony, and L. Xiaofang. 2002. Intravenous micro-particle injections and pulmonary hypertension in broiler chickens: Acute post-injection mortality and ascites susceptibility. Poult. Sci. 81:1203-1217.
52. Wideman, R. F., Y. K. Kirby, M. F. Forman, N. Marson, R. W. McNew, and R. L. Owen. 1998a. The infusion rate dependent influence of acute metabolic acidosis on pulmonary vascular resistance in broilers. Poult. Sci. 77:309-321.
53. Wideman, R. F., Y. K. Kirby, C. D. Tacket, N. E. Marson, and R. W. McNew. 1996. Cardio-pulmonary function during acute unilateral occlusion of the pulmonary artery in broilers fed diets containing normal or high levels of arginine-HCl. Poult. Sci. 79:257-264.
54. Wideman, R. F., P. Maynard, and W. G. Bottje. 1999a. Thromboxane mimics the pulmonary but not systemic vascular responses to bolus HCl injections in broiler chickens. Poult. Sci. 78:714-721.
55. Xie, H., N. C. Rath, G. R. Huff, W. E. Huff, and J. M. Balog. 2000. Effects of Salmonella typhimurium lipopolysaccharide on broiler chickens. Poult. Sci. 79:33-40.