Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity

Virology

Volumn 371, Issue 1, 2008, Pages 71-85

  Sekine Osajima, Yuko ^a   Sakamoto, Naoya ^a   Mishima, Kako ^a   Nakagawa, Mina ^a   Itsui, Yasuhiro ^a   Tasaka, Megumi ^a   Nishimura Sakurai, Yuki ^a   Chen, Cheng Hsin ^a   Kanai, Takanori ^a   Tsuchiya, Kiichiro ^a   Wakita, Takaji ^b   Enomoto, Nobuyuki ^c   Watanabe, Mamoru ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Apoptosis; ER stress; HCV cell culture; HCV JFH1; NS5B RNA dependent RNA polymerase; Plaque assay; Unfolded protein responses

Indexed keywords

APOPTOSIS; ARTICLE; CYTOPATHOGENIC EFFECT; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS CULTURE; VIRUS ISOLATION; VIRUS REPLICATION;

AMINO ACID SUBSTITUTION; ANNEXIN A5; APOPTOSIS; CELL LINE, TUMOR; CYTOPATHOGENIC EFFECT, VIRAL; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; FLUORESCENT DYES; GENTIAN VIOLET; HEAT-SHOCK PROTEINS; HEPACIVIRUS; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; MOLECULAR CHAPERONES; PLAQUE ASSAY; REPLICON; RNA, VIRAL; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; VIRAL PROTEINS; VIRUS REPLICATION;

HEPATITIS C VIRUS;

EID: 37849040237     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.09.019     Document Type: Article

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