TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest

Oncogene

Volumn 27, Issue 1, 2008, Pages 116-125

  Schneider, L ^a   Essmann, F ^a   Kletke, A ^a   Rio, P ^a,c   Hanenberg, H ^a,b   Schulze Osthoff, K ^a   Nurnberg B ^a   Piekorz, R P ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CIEMAT   (Spain)

Author keywords

Apoptosis; Mitosis; p21WAF; p53; Paclitaxel; TACC3

Indexed keywords

CELL PROTEIN; CENTROSOMAL PROTEIN TRANSFORMING ACIDIC COILED COIL 3 PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYTOPLASM PROTEIN; DOXYCYCLINE; PACLITAXEL; PROTEIN KINASE B; PROTEIN TACC3; UNCLASSIFIED DRUG;

ANEUPLOIDY; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE ARREST; CELL DEATH; CELL TRANSFORMATION; CHROMOSOME SEGREGATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE COURSE; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MITOSIS SPINDLE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYPLOIDY; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARRIER PROTEINS; CELL CYCLE; CELL DEATH; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; FETAL PROTEINS; HUMANS; MICE; NIH 3T3 CELLS; PACLITAXEL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 37849038558     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210628     Document Type: Article

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