-
2
-
-
0034694088
-
BAFF mediates survival of peripheral immature B lymphocytes
-
11085747
-
Batten M Groom J Cachero TG Qian F Schneider P Tschopp J Browning JL Mackay F BAFF mediates survival of peripheral immature B lymphocytes J Exp Med 2000, 192:1453-1465. 11085747
-
(2000)
J Exp Med
, vol.192
, pp. 1453-1465
-
-
Batten, M.1
Groom, J.2
Cachero, T.G.3
Qian, F.4
Schneider, P.5
Tschopp, J.6
Browning, J.L.7
Mackay, F.8
-
3
-
-
3342921914
-
The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers
-
15251127
-
Mackay F Tangye SG The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers Curr Opin Pharmacol 2004, 4:347-354. 15251127
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 347-354
-
-
Mackay, F.1
Tangye, S.G.2
-
4
-
-
0036144353
-
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
-
150825 11781351
-
Groom J Kalled SL Cutler AH Olson C Woodcock SA Schneider P Tschopp J Cachero TG Batten M Wheway J Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome J Clin Invest 2002, 109:59-68. 150825 11781351
-
(2002)
J Clin Invest
, vol.109
, pp. 59-68
-
-
Groom, J.1
Kalled, S.L.2
Cutler, A.H.3
Olson, C.4
Woodcock, S.A.5
Schneider, P.6
Tschopp, J.7
Cachero, T.G.8
Batten, M.9
Wheway, J.10
-
5
-
-
33748441252
-
Alternative and classical NF-κB signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease
-
16973390
-
Enzler T Bonizzi G Silverman GJ Otero DC Widhopf GF Anzelon-Mills A Rickert RC Karin M Alternative and classical NF-κB signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease Immunity 2006, 25:403-415. 16973390
-
(2006)
Immunity
, vol.25
, pp. 403-415
-
-
Enzler, T.1
Bonizzi, G.2
Silverman, G.J.3
Otero, D.C.4
Widhopf, G.F.5
Anzelon-Mills, A.6
Rickert, R.C.7
Karin, M.8
-
6
-
-
84856488806
-
Crossroads of B cell activation in autoimmunity: Rationale of targeting B cells
-
16652439
-
Dorner T Crossroads of B cell activation in autoimmunity: Rationale of targeting B cells J Rheumatol Suppl 2006, 77:3-11. 16652439
-
(2006)
J Rheumatol Suppl
, vol.77
, pp. 3-11
-
-
Dorner, T.1
-
7
-
-
33644660402
-
Similarities and differences between selective and nonselective BAFF blockade in murine SLE
-
1366500 16485042
-
Ramanujam M Wang XB Huang WQ Liu Z Schiffer L Tao HO Frank D Rice J Diamond B Yu KO Similarities and differences between selective and nonselective BAFF blockade in murine SLE J Clin Invest 2006, 116:724-734. 1366500 16485042
-
(2006)
J Clin Invest
, vol.116
, pp. 724-734
-
-
Ramanujam, M.1
Wang, X.B.2
Huang, W.Q.3
Liu, Z.4
Schiffer, L.5
Tao, H.O.6
Frank, D.7
Rice, J.8
Diamond, B.9
Yu, K.O.10
-
8
-
-
33644505807
-
Hormonal regulation of B cell development: 17β-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint
-
16493025
-
Grimaldi CM Jeganathan V Diamond B Hormonal regulation of B cell development: 17β-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint J Immunol 2006, 176:2703-2710. 16493025
-
(2006)
J Immunol
, vol.176
, pp. 2703-2710
-
-
Grimaldi, C.M.1
Jeganathan, V.2
Diamond, B.3
-
9
-
-
35648975634
-
Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host disease
-
1779408 16859527
-
Kuroiwa T Iwasaki T Imado T Sekiguchi M Fujimoto J Sano H Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host disease Arthritis Res Ther 2006, 8:R123. 1779408 16859527
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Kuroiwa, T.1
Iwasaki, T.2
Imado, T.3
Sekiguchi, M.4
Fujimoto, J.5
Sano, H.6
-
10
-
-
33748117796
-
Interleukin-6: Discovery of a pleiotropic cytokine
-
16899106
-
Kishimoto T Interleukin-6: Discovery of a pleiotropic cytokine Arthritis Res Ther 2006, 8(Suppl 2):S2. 16899106
-
(2006)
Arthritis Res Ther
, vol.8
, Issue.SUPPL. 2
-
-
Kishimoto, T.1
-
11
-
-
33748092926
-
Interleukin-6 and rheumatic diseases
-
16899108
-
Lipsky PE Interleukin-6 and rheumatic diseases Arthritis Res Ther 2006, 8(Suppl 2):S4. 16899108
-
(2006)
Arthritis Res Ther
, vol.8
, Issue.SUPPL. 2
-
-
Lipsky, P.E.1
-
13
-
-
33144467291
-
Targeting toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus
-
1526546 16542467
-
Lenert PS Targeting toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus Arthritis Res Ther 2006, 8:203. 1526546 16542467
-
(2006)
Arthritis Res Ther
, vol.8
, pp. 203
-
-
Lenert, P.S.1
-
14
-
-
33845236216
-
Ligands to nucleic acid-specific toll-like receptors and the onset of lupus nephritis
-
17082246
-
Pawar RD Patole PS Ellwart A Lech M Segerer S Schlondorff D Anders HJ Ligands to nucleic acid-specific toll-like receptors and the onset of lupus nephritis J Am Soc Nephrol 2006, 17:3365-3373. 17082246
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 3365-3373
-
-
Pawar, R.D.1
Patole, P.S.2
Ellwart, A.3
Lech, M.4
Segerer, S.5
Schlondorff, D.6
Anders, H.J.7
-
15
-
-
33745864016
-
Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus
-
16818796
-
Lartigue A Courville P Auquit I Francois A Arnoult C Tron F Gilbert D Musette P Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus J Immunol 2006, 177:1349-1354. 16818796
-
(2006)
J Immunol
, vol.177
, pp. 1349-1354
-
-
Lartigue, A.1
Courville, P.2
Auquit, I.3
Francois, A.4
Arnoult, C.5
Tron, F.6
Gilbert, D.7
Musette, P.8
-
16
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
16973389
-
Christensen SR Shupe J Nickerson K Kashgarian M Flavell RA Shlomchik MJ Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus Immunity 2006, 25:417-428. 16973389
-
(2006)
Immunity
, vol.25
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
Kashgarian, M.4
Flavell, R.A.5
Shlomchik, M.J.6
-
17
-
-
33748470505
-
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
-
16973388
-
Berland R Fernandez L Kari E Han JH Lomakin I Akira S Wortis HH Kearney JF Ucci AA Imanishi-Kari T Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice Immunity 2006, 25:429-440. 16973388
-
(2006)
Immunity
, vol.25
, pp. 429-440
-
-
Berland, R.1
Fernandez, L.2
Kari, E.3
Han, J.H.4
Lomakin, I.5
Akira, S.6
Wortis, H.H.7
Kearney, J.F.8
Ucci, A.A.9
Imanishi-Kari, T.10
-
19
-
-
33745617886
-
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
-
1502563 16777955
-
Subramanian S Tus K Li QZ Wang A Tian XH Zhou J Liang C Bartov G McDaniel LD Zhou XJ A Tlr7 translocation accelerates systemic autoimmunity in murine lupus Proc Natl Acad Sci USA 2006, 103:9970-9975. 1502563 16777955
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9970-9975
-
-
Subramanian, S.1
Tus, K.2
Li, Q.Z.3
Wang, A.4
Tian, X.H.5
Zhou, J.6
Liang, C.7
Bartov, G.8
McDaniel, L.D.9
Zhou, X.J.10
-
20
-
-
33645076274
-
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
-
16492804
-
Ehlers M Fukuyama H Mcgaha TL Aderem A Ravetch JV TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE J Exp Med 2006, 203:553-561. 16492804
-
(2006)
J Exp Med
, vol.203
, pp. 553-561
-
-
Ehlers, M.1
Fukuyama, H.2
Mcgaha, T.L.3
Aderem, A.4
Ravetch, J.V.5
-
21
-
-
22544487815
-
FcγRIV: A novel FcR with distinct IgG subclass specificity
-
16039578
-
Nimmerjahn F Bruhns P Horiuchi K Ravetch JV FcγRIV: A novel FcR with distinct IgG subclass specificity Immunity 2005, 23: 41-51 16039578
-
(2005)
Immunity
, vol.23
, pp. 41-51
-
-
Nimmerjahn, F.1
Bruhns, P.2
Horiuchi, K.3
Ravetch, J.V.4
-
22
-
-
33751564664
-
TLR2/TLR4-independent neutrophil activation and recruitment upon endocytosis of nucleosomes reveals a new pathway of innate immunity in systemic lupus erythematosus
-
17114445
-
Rönnefarth VM Erbacher AI Lamkemeyer T Madlung J Nordheim A Rammensee HG Decker P TLR2/TLR4-independent neutrophil activation and recruitment upon endocytosis of nucleosomes reveals a new pathway of innate immunity in systemic lupus erythematosus J Immunol 2006, 177:7740-7749. 17114445
-
(2006)
J Immunol
, vol.177
, pp. 7740-7749
-
-
Rönnefarth, V.M.1
Erbacher, A.I.2
Lamkemeyer, T.3
Madlung, J.4
Nordheim, A.5
Rammensee, H.G.6
Decker, P.7
-
23
-
-
34247550779
-
Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus
-
1526610 16507174
-
Colonna L Dinnall JA Shivers DK Frisoni L Caricchio R Gallucci S Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus Arthritis Res Ther 2006, 8:R49. 1526610 16507174
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Colonna, L.1
Dinnall, J.A.2
Shivers, D.K.3
Frisoni, L.4
Caricchio, R.5
Gallucci, S.6
-
24
-
-
17544373868
-
Systemic lupus erythematosus arising during interferon-α therapy for cryoglobulinemic vasculitis associated with hepatitis C
-
15565395
-
Niewold TB Swedler WI Systemic lupus erythematosus arising during interferon-α therapy for cryoglobulinemic vasculitis associated with hepatitis C Clin Rheumatol 2005, 24:178-181. 15565395
-
(2005)
Clin Rheumatol
, vol.24
, pp. 178-181
-
-
Niewold, T.B.1
Swedler, W.I.2
-
25
-
-
0035423557
-
An etiopathogenic role for the type IIFN system in SLE
-
11473831
-
Rönnblom L Alm GV An etiopathogenic role for the type IIFN system in SLE Trends Immunol 2001, 22:427-431. 11473831
-
(2001)
Trends Immunol
, vol.22
, pp. 427-431
-
-
Rönnblom, L.1
Alm, G.V.2
-
26
-
-
0038639795
-
Systemic lupus erythematosus and the type I interferon system
-
165035 12718746
-
Rönnblom L Alm GV Systemic lupus erythematosus and the type I interferon system Arthritis Res Ther 2003, 5:68-75. 165035 12718746
-
(2003)
Arthritis Res Ther
, vol.5
, pp. 68-75
-
-
Rönnblom, L.1
Alm, G.V.2
-
27
-
-
3242805826
-
Type I IFN protects against murine lupus
-
15265950
-
Hron JD Peng SL Type I IFN protects against murine lupus J Immunol 2004, 173:2134-2142. 15265950
-
(2004)
J Immunol
, vol.173
, pp. 2134-2142
-
-
Hron, J.D.1
Peng, S.L.2
-
28
-
-
26844573357
-
Deficiency of type I interferon contributes to Sle2-associated component lupus phenotypes
-
16200585
-
Li J Liu Y Xie C Zhu J Kreska D Morel L Mohan C Deficiency of type I interferon contributes to Sle2-associated component lupus phenotypes Arthritis Rheum 2005, 52:3063-3072. 16200585
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3063-3072
-
-
Li, J.1
Liu, Y.2
Xie, C.3
Zhu, J.4
Kreska, D.5
Morel, L.6
Mohan, C.7
-
29
-
-
33749331301
-
Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus
-
16947629
-
Feng X Wu H Grossman JM Hanvivadhanakul P FitzGerald JD Park GS Dong X Chen W Kim MH Weng HH Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus Arthritis Rheum 2006, 54:2951-2962. 16947629
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2951-2962
-
-
Feng, X.1
Wu, H.2
Grossman, J.M.3
Hanvivadhanakul, P.4
FitzGerald, J.D.5
Park, G.S.6
Dong, X.7
Chen, W.8
Kim, M.H.9
Weng, H.H.10
-
30
-
-
33644530664
-
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjogren's syndrome
-
1413808 16477017
-
Gottenberg JE Cagnard N Lucchesi C Letourneur F Mistou S Lazure T Jacques S Ba N Ittah M Lepajolec C Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjogren's syndrome Proc Natl Acad Sci USA 2006, 103:2770-2775. 1413808 16477017
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2770-2775
-
-
Gottenberg, J.E.1
Cagnard, N.2
Lucchesi, C.3
Letourneur, F.4
Mistou, S.5
Lazure, T.6
Jacques, S.7
Ba, N.8
Ittah, M.9
Lepajolec, C.10
-
32
-
-
17244372491
-
Activation of the type I interferon system in primary Sjogren's syndrome - A possible etiopathogenic mechanism
-
15818675
-
Båve U Nordmark G Lövgren T Rönnelid J Cajander S Eloranta ML Alm GV Rönnblom L Activation of the type I interferon system in primary Sjogren's syndrome - a possible etiopathogenic mechanism Arthritis Rheum 2005, 52:1185-1195. 15818675
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1185-1195
-
-
Båve, U.1
Nordmark, G.2
Lövgren, T.3
Rönnelid, J.4
Cajander, S.5
Eloranta, M.L.6
Alm, G.V.7
Rönnblom, L.8
-
33
-
-
0035403969
-
Plasmacytoid dendritic cells (natural interferon-α/ β-producing cells) accumulate in cutaneous lupus erythematosus lesions
-
1850412 11438470
-
Farkas L Beiske K Lund-Johansen F Brandtzaeg P Jahnsen FL Plasmacytoid dendritic cells (natural interferon-α/β-producing cells) accumulate in cutaneous lupus erythematosus lesions Am J Pathol 2001, 159:237-243. 1850412 11438470
-
(2001)
Am J Pathol
, vol.159
, pp. 237-243
-
-
Farkas, L.1
Beiske, K.2
Lund-Johansen, F.3
Brandtzaeg, P.4
Jahnsen, F.L.5
-
34
-
-
26844467349
-
Nucleic acids of mammalian origin can act as endogenous ligands for toll-like receptors and may promote systemic lupus erythematosus
-
16230478
-
Barrat FJ Meeker T Gregorio J Chan JH Uematsu S Akira S Chang B Duramad O Coffman RL Nucleic acids of mammalian origin can act as endogenous ligands for toll-like receptors and may promote systemic lupus erythematosus J Exp Med 2005, 202:1131-1139. 16230478
-
(2005)
J Exp Med
, vol.202
, pp. 1131-1139
-
-
Barrat, F.J.1
Meeker, T.2
Gregorio, J.3
Chan, J.H.4
Uematsu, S.5
Akira, S.6
Chang, B.7
Duramad, O.8
Coffman, R.L.9
-
35
-
-
33745161013
-
Regulation of B cell tolerance by the lupus susceptibility gene Ly108
-
16778059
-
Kumar KR Li L Yan M Bhaskarabhatla M Mobley AB Nguyen C Mooney JM Schatzle JD Wakeland EK Mohan C Regulation of B cell tolerance by the lupus susceptibility gene Ly108 Science 2006, 312:1665-1669. 16778059
-
(2006)
Science
, vol.312
, pp. 1665-1669
-
-
Kumar, K.R.1
Li, L.2
Yan, M.3
Bhaskarabhatla, M.4
Mobley, A.B.5
Nguyen, C.6
Mooney, J.M.7
Schatzle, J.D.8
Wakeland, E.K.9
Mohan, C.10
-
36
-
-
33646368404
-
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
-
16642019
-
Graham RR Kozyrev SV Baechler EC Reddy MV Plenge RM Bauer JW Ortmann WA Koeuth T González Escribano MF Argentine and Spanish Collaborative Groups A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus Nat Genet 2006, 38:550-555. 16642019
-
(2006)
Nat Genet
, vol.38
, pp. 550-555
-
-
Graham, R.R.1
Kozyrev, S.V.2
Baechler, E.C.3
Reddy, M.V.4
Plenge, R.M.5
Bauer, J.W.6
Ortmann, W.A.7
Koeuth, T.8
González Escribano, M.F.9
-
37
-
-
34447099218
-
Systemic lupus erythematosus: Multiple immunological phenotypes in a complex genetic disease
-
17145301
-
Fairhurst AM Wandstrat AE Wakeland EK Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease Adv Immunol 2006, 92:1-69. 17145301
-
(2006)
Adv Immunol
, vol.92
, pp. 1-69
-
-
Fairhurst, A.M.1
Wandstrat, A.E.2
Wakeland, E.K.3
-
38
-
-
33750376202
-
Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus
-
16971955
-
Forabosco P Gorman JD Cleveland C Kelly JA Fisher SA Ortmann WA Johansson C Johanneson B Moser KL Gaffney PM Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus Genes Immun 2006, 7:609-614. 16971955
-
(2006)
Genes Immun
, vol.7
, pp. 609-614
-
-
Forabosco, P.1
Gorman, J.D.2
Cleveland, C.3
Kelly, J.A.4
Fisher, S.A.5
Ortmann, W.A.6
Johansson, C.7
Johanneson, B.8
Moser, K.L.9
Gaffney, P.M.10
-
39
-
-
34948862550
-
Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs
-
1526590 16507146
-
Lopez P Gomez J Mozo L Gutierrez C Suarez A Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs Arthritis Res Ther 2006, 8:R42. 1526590 16507146
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Lopez, P.1
Gomez, J.2
Mozo, L.3
Gutierrez, C.4
Suarez, A.5
-
40
-
-
33646239397
-
Association of smoking with dsDNA autoantibody production in systemic lupus erythematosus
-
16150789
-
Freemer MM King TE Criswell LA Association of smoking with dsDNA autoantibody production in systemic lupus erythematosus Ann Rheum Dis 2006, 65:581-584. 16150789
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 581-584
-
-
Freemer, M.M.1
King, T.E.2
Criswell, L.A.3
-
41
-
-
0034760335
-
Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: A case-control study
-
11708417
-
Ghaussy NO Sibbitt WL Qualls CR Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: A case-control study J Rheumatol 2001, 28:2449-2453. 11708417
-
(2001)
J Rheumatol
, vol.28
, pp. 2449-2453
-
-
Ghaussy, N.O.1
Sibbitt, W.L.2
Qualls, C.R.3
-
42
-
-
33646265065
-
Cigarette smoking and the risk of systemic lupus erythematosus and rheumatoid arthritis
-
16611864
-
Majka DS Holers VM Cigarette smoking and the risk of systemic lupus erythematosus and rheumatoid arthritis Ann Rheum Dis 2006, 65:561-563. 16611864
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 561-563
-
-
Majka, D.S.1
Holers, V.M.2
-
43
-
-
33748467673
-
Selective dysregulation of the FcγIIB receptor on memory B cells in SLE
-
16923849
-
Mackay M Stanevsky A Wang T Aranow C Li M Koenig S Ravetch JV Diamond B Selective dysregulation of the FcγIIB receptor on memory B cells in SLE J Exp Med 2006, 203:2157-2164. 16923849
-
(2006)
J Exp Med
, vol.203
, pp. 2157-2164
-
-
Mackay, M.1
Stanevsky, A.2
Wang, T.3
Aranow, C.4
Li, M.5
Koenig, S.6
Ravetch, J.V.7
Diamond, B.8
-
44
-
-
33747082349
-
Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial
-
16820790
-
Grootscholten C Ligtenberg G Hagen EC van den Wall Bake AW de Glas-Vos JW Bijl M Assmann KJ Bruijn JA Weening JJ van Houwelingen HC Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial Kidney Int 2006, 70:732-742. 16820790
-
(2006)
Kidney Int
, vol.70
, pp. 732-742
-
-
Grootscholten, C.1
Ligtenberg, G.2
Hagen, E.C.3
van den Wall Bake, A.W.4
de Glas-Vos, J.W.5
Bijl, M.6
Assmann, K.J.7
Bruijn, J.A.8
Weening, J.J.9
van Houwelingen, H.C.10
-
45
-
-
33750936797
-
The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus - Findings of a prospective, randomized, double-blind, placebo-controlled trial
-
17075807
-
Tseng CE Buyon JP Kim M Belmont HM Mackay M Diamond B Marder G Rosenthal P Haines K Ilie V Abramson SB The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus - findings of a prospective, randomized, double-blind, placebo-controlled trial Arthritis Rheum 2006, 54:3623-3632. 17075807
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3623-3632
-
-
Tseng, C.E.1
Buyon, J.P.2
Kim, M.3
Belmont, H.M.4
Mackay, M.5
Diamond, B.6
Marder, G.7
Rosenthal, P.8
Haines, K.9
Ilie, V.10
Abramson, S.B.11
-
46
-
-
37849011506
-
The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus
-
1779394 16859514
-
Fritsch-Stork R Mullegger D Skriner K Jahn-Schmid B Smolen JS Steiner G The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus Arthritis Res Ther 2006, 8:R118. 1779394 16859514
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Fritsch-Stork, R.1
Mullegger, D.2
Skriner, K.3
Jahn-Schmid, B.4
Smolen, J.S.5
Steiner, G.6
-
47
-
-
34247551065
-
Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: Possible involvement in excessive interferon-γ and anti-double-stranded DNA antibody production
-
1526621 16563187
-
Kawamoto M Harigai M Hara M Kawaguchi Y Tezuka K Tanaka M Sugiura T Katsumata Y Fukasawa C Ichida H Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: Possible involvement in excessive interferon-γ and anti-double-stranded DNA antibody production Arthritis Res Ther 2006, 8:R62. 1526621 16563187
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Kawamoto, M.1
Harigai, M.2
Hara, M.3
Kawaguchi, Y.4
Tezuka, K.5
Tanaka, M.6
Sugiura, T.7
Katsumata, Y.8
Fukasawa, C.9
Ichida, H.10
-
48
-
-
5644273872
-
Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus
-
15476242
-
Hutloff A Büchner K Reiter K Baelde HJ Odendahl M Jacobi A Dörner T Kroczek RA Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus Arthritis Rheum 2004, 50:3211-3220. 15476242
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3211-3220
-
-
Hutloff, A.1
Büchner, K.2
Reiter, K.3
Baelde, H.J.4
Odendahl, M.5
Jacobi, A.6
Dörner, T.7
Kroczek, R.A.8
-
49
-
-
0041331737
-
Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis
-
12960306
-
Iwai H Abe M Hirose S Tsushima F Tezuka K Akiba H Yagita H Okumura K Kohsaka H Miyasaka N Azuma M Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis J Immunol 2003, 171:2848-2854. 12960306
-
(2003)
J Immunol
, vol.171
, pp. 2848-2854
-
-
Iwai, H.1
Abe, M.2
Hirose, S.3
Tsushima, F.4
Tezuka, K.5
Akiba, H.6
Yagita, H.7
Okumura, K.8
Kohsaka, H.9
Miyasaka, N.10
Azuma, M.11
-
50
-
-
33749349457
-
Persistent expression of autoantibodies in SLE patients in remission
-
16966430
-
Yurasov S Tiller T Tsuiji M Velinzon K Pascual V Wardemann H Nussenzweig MC Persistent expression of autoantibodies in SLE patients in remission J Exp Med 2006, 203:2255-2261. 16966430
-
(2006)
J Exp Med
, vol.203
, pp. 2255-2261
-
-
Yurasov, S.1
Tiller, T.2
Tsuiji, M.3
Velinzon, K.4
Pascual, V.5
Wardemann, H.6
Nussenzweig, M.C.7
-
51
-
-
33750587819
-
Traditional and non-traditional risk factors contribute to the development of accelerated atherosclerosis in patients with systemic lupus erythematosus
-
17120595
-
de Leeuw K Freire B Srnit AJ Bootsma H Kallenberg CG Bijl M Traditional and non-traditional risk factors contribute to the development of accelerated atherosclerosis in patients with systemic lupus erythematosus Lupus 2006, 15:675-682. 17120595
-
(2006)
Lupus
, vol.15
, pp. 675-682
-
-
de Leeuw, K.1
Freire, B.2
Srnit, A.J.3
Bootsma, H.4
Kallenberg, C.G.5
Bijl, M.6
-
52
-
-
33744542226
-
Impact of antiphospholipid antibodies on cardiovascular disease in systemic lupus erythematosus
-
[abstract]
-
Farzaneh-Far A Roman MJ Lockshin MD Devereux RB Paget SA Crow MK Davis A Sammaritano L Levine DM Salmon JE Impact of antiphospholipid antibodies on cardiovascular disease in systemic lupus erythematosus [abstract] J Am Coll Cardiol 2006, 47(Suppl A):277A.
-
(2006)
J Am Coll Cardiol
, vol.47
, Issue.SUPPL. A
-
-
Farzaneh-Far, A.1
Roman, M.J.2
Lockshin, M.D.3
Devereux, R.B.4
Paget, S.A.5
Crow, M.K.6
Davis, A.7
Sammaritano, L.8
Levine, D.M.9
Salmon, J.E.10
-
53
-
-
33645940600
-
Particularities of the vasculature can promote the organ specificity of autoimmune attack
-
16444258
-
Binstadt BA Patel PR Alencar H Nigrovic PA Lee DM Mahmood U Weissleder R Mathis D Benoist C Particularities of the vasculature can promote the organ specificity of autoimmune attack Nature Immunology 2006, 7:284-292. 16444258
-
(2006)
Nature Immunology
, vol.7
, pp. 284-292
-
-
Binstadt, B.A.1
Patel, P.R.2
Alencar, H.3
Nigrovic, P.A.4
Lee, D.M.5
Mahmood, U.6
Weissleder, R.7
Mathis, D.8
Benoist, C.9
-
54
-
-
34447522347
-
Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus
-
1526639 16646981
-
Jackson M Ahmad Y Bruce IN Coupes B Brenchley PEC Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus Arthritis Res Ther 2006, 8:R81. 1526639 16646981
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Jackson, M.1
Ahmad, Y.2
Bruce, I.N.3
Coupes, B.4
Brenchley, P.E.C.5
-
55
-
-
28144433147
-
Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis
-
16306519
-
Ginzler EM Dooley MA Aranow C Kim MY Buyon J Merrill JT Petri M Gilkeson GS Wallace DJ Weisman MH Appel GB Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis N Engl J Med 2005, 353:2219-2228. 16306519
-
(2005)
N Engl J Med
, vol.353
, pp. 2219-2228
-
-
Ginzler, E.M.1
Dooley, M.A.2
Aranow, C.3
Kim, M.Y.4
Buyon, J.5
Merrill, J.T.6
Petri, M.7
Gilkeson, G.S.8
Wallace, D.J.9
Weisman, M.H.10
Appel, G.B.11
-
56
-
-
33847193118
-
Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis
-
1794528 17163990
-
Moore RA Derry S Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis Arthritis Res Ther 2006, 8:R182. 1794528 17163990
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Moore, R.A.1
Derry, S.2
-
57
-
-
33751523267
-
New immune modulatory drugs for systemic lupus erythematosus - What can we expect?
-
17133245
-
Davidson A New immune modulatory drugs for systemic lupus erythematosus - what can we expect? Nat Clin Pract Rheumatol 2006, 2:638-639. 17133245
-
(2006)
Nat Clin Pract Rheumatol
, vol.2
, pp. 638-639
-
-
Davidson, A.1
-
58
-
-
33646438805
-
B cell targeted therapies in autoimmune diseases
-
16652442
-
Isenberg DA B cell targeted therapies in autoimmune diseases J Rheumatol 2006, 33(Suppl 77):24-28. 16652442
-
(2006)
J Rheumatol
, vol.33
, Issue.SUPPL. 77
, pp. 24-28
-
-
Isenberg, D.A.1
-
59
-
-
33745010247
-
Signalling pathways in B cells: Implications for autoimmunity
-
Dorner T Lipsky PE Signalling pathways in B cells: Implications for autoimmunity Curr Concepts Autoimmun Chron Inflamm 2006, 305:213-240.
-
(2006)
Curr Concepts Autoimmun Chron Inflamm
, vol.305
, pp. 213-240
-
-
Dorner, T.1
Lipsky, P.E.2
-
60
-
-
0242495115
-
Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator
-
Baker KP Edwards BM Main SH Choi GH Wager RE Halpern WG Lappin PB Riccobene T Abramian D Sekut L Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator Arthritis Rheum 2003 48 3253 3265 14613291
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3253-3265
-
-
Baker, K.P.1
Edwards, B.M.2
Main, S.H.3
Choi, G.H.4
Wager, R.E.5
Halpern, W.G.6
Lappin, P.B.7
Riccobene, T.8
Abramian, D.9
Sekut, L.10
-
61
-
-
33646827589
-
Chronic administration of belimumab, a BLyS antagonist, decreases tissue and peripheral blood B-lymphocyte populations in cynomolgus monkeys: Pharmacokinetic,pharmacodynamic, and toxicologic effects
-
16517838
-
Halpern WG Lappin P Zanardi T Cai W Corcoran M Zhong J Baker KP Chronic administration of belimumab, a BLyS antagonist, decreases tissue and peripheral blood B-lymphocyte populations in cynomolgus monkeys: pharmacokinetic, pharmacodynamic, and toxicologic effects Toxicol Sci 2006, 91:586-599. 16517838
-
(2006)
Toxicol Sci
, vol.91
, pp. 586-599
-
-
Halpern, W.G.1
Lappin, P.2
Zanardi, T.3
Cai, W.4
Corcoran, M.5
Zhong, J.6
Baker, K.P.7
-
63
-
-
33749018225
-
Competence and competition: The challenge of becoming a long-lived plasma cell
-
16977339
-
Radbruch A Muehlinghaus G Luger EO Inamine A Smith KG Dörner T Hiepe F Competence and competition: The challenge of becoming a long-lived plasma cell Nat Rev Immunol 2006, 6:741-750. 16977339
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 741-750
-
-
Radbruch, A.1
Muehlinghaus, G.2
Luger, E.O.3
Inamine, A.4
Smith, K.G.5
Dörner, T.6
Hiepe, F.7
-
64
-
-
24344510429
-
Remission of proliferative lupus nephritis following anti-B cell therapy is preceded by downregulation of the T cell costimulatory molecule CD40-ligand
-
Sfikakis PP Boletis JN Lionaki S Vigklis V Fragiadaki KG Iniotaki A Moutsopoulos HM Remission of proliferative lupus nephritis following anti-B cell therapy is preceded by downregulation of the T cell costimulatory molecule CD40-ligand Arthritis Rheum 2004, 50(Suppl):S227.
-
(2004)
Arthritis Rheum
, vol.50
, Issue.SUPPL.
-
-
Sfikakis, P.P.1
Boletis, J.N.2
Lionaki, S.3
Vigklis, V.4
Fragiadaki, K.G.5
Iniotaki, A.6
Moutsopoulos, H.M.7
-
66
-
-
33750964016
-
B cell depletion therapy in systemic lupus erythematosus - Effect on autoantibody and antimicrobial antibody profiles
-
17075806
-
Cambridge G Leandro MJ Teodorescu M Manson J Rahman A Isenberg DA Edwards JC B cell depletion therapy in systemic lupus erythematosus - effect on autoantibody and antimicrobial antibody profiles Arthritis Rheum 2006, 54:3612-3622. 17075806
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3612-3622
-
-
Cambridge, G.1
Leandro, M.J.2
Teodorescu, M.3
Manson, J.4
Rahman, A.5
Isenberg, D.A.6
Edwards, J.C.7
-
68
-
-
70350520105
-
B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: Disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels
-
1526545 16356193
-
Collins CE Gavin AL Migone TS Hilbert DM Nemazee D Stohl W B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: Disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels Arthritis Res Ther 2006, 8:R6. 1526545 16356193
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Collins, C.E.1
Gavin, A.L.2
Migone, T.S.3
Hilbert, D.M.4
Nemazee, D.5
Stohl, W.6
-
70
-
-
53749095799
-
Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
-
1526638 16630358
-
Dorner T Kaufmann J Wegener WA Teoh N Goldenberg DM Burmester GR Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus Arthritis Res Ther 2006, 8:R74. 1526638 16630358
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Dorner, T.1
Kaufmann, J.2
Wegener, W.A.3
Teoh, N.4
Goldenberg, D.M.5
Burmester, G.R.6
-
72
-
-
28944445445
-
Combined oral contraceptives in women with systemic lupus erythematosus
-
16354891
-
Petri M Kim MY Kalunian KC Grossman J Hahn BH Sammaritano LR Lockshin M Merrill JT Belmont HM Askanase AD Combined oral contraceptives in women with systemic lupus erythematosus N Engl J Med 2005, 353:2550-2558. 16354891
-
(2005)
N Engl J Med
, vol.353
, pp. 2550-2558
-
-
Petri, M.1
Kim, M.Y.2
Kalunian, K.C.3
Grossman, J.4
Hahn, B.H.5
Sammaritano, L.R.6
Lockshin, M.7
Merrill, J.T.8
Belmont, H.M.9
Askanase, A.D.10
-
73
-
-
0029020939
-
Prevention of relapses in systemic lupus-erythematosus
-
7783536
-
Bootsma H Spronk P Derksen R de Boer G Wolters-Dicke H Hermans J Limburg P Gmelig-Meyling F Kater L Kallenberg C Prevention of relapses in systemic lupus-erythematosus Lancet 1995, 345:1595-1599. 7783536
-
(1995)
Lancet
, vol.345
, pp. 1595-1599
-
-
Bootsma, H.1
Spronk, P.2
Derksen, R.3
de Boer, G.4
Wolters-Dicke, H.5
Hermans, J.6
Limburg, P.7
Gmelig-Meyling, F.8
Kater, L.9
Kallenberg, C.10
-
74
-
-
37849039400
-
The role of long-lived plasma cells in autoimmunity
-
Hiepe F Manz RA Radbruch A The role of long-lived plasma cells in autoimmunity Ann Rheumatic Dis 2004, 63:16-17.
-
(2004)
Ann Rheumatic Dis
, vol.63
, pp. 16-17
-
-
Hiepe, F.1
Manz, R.A.2
Radbruch, A.3
-
75
-
-
37849011507
-
Impact of cellular therapies on autoreactive, long-lived plasma cells in autoimmune diseases
-
Hoyer BF Manz RA Radbruch A Hiepe F Impact of cellular therapies on autoreactive, long-lived plasma cells in autoimmune diseases Bone Marrow Transplant 2004, 33:S26.
-
(2004)
Bone Marrow Transplant
, vol.33
-
-
Hoyer, B.F.1
Manz, R.A.2
Radbruch, A.3
Hiepe, F.4
-
76
-
-
33947271519
-
Development of a secondary autoimmune disorder after hematopoeitic stem cell transplantation for autoimmune diseases: Role of conditioning regimen used
-
17119125
-
Loh Y Oyama Y Statkute L Quigley K Yaung K Gonda E Barr W Jovanovic B Craig R Stefoski D Development of a secondary autoimmune disorder after hematopoeitic stem cell transplantation for autoimmune diseases: Role of conditioning regimen used Blood 2007, 109:2643-2648. 17119125
-
(2007)
Blood
, vol.109
, pp. 2643-2648
-
-
Loh, Y.1
Oyama, Y.2
Statkute, L.3
Quigley, K.4
Yaung, K.5
Gonda, E.6
Barr, W.7
Jovanovic, B.8
Craig, R.9
Stefoski, D.10
|