Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host disease

Arthritis Research and Therapy

Volumn 8, Issue 4, 2006, Pages

  Kuroiwa, Takanori ^a   Iwasaki, Tsuyoshi ^a   Imado, Takehito ^a   Sekiguchi, Masahiro ^a   Fujimoto, Jiro ^a   Sano, Hajime ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; CD28 ANTIGEN; DNA; HLA ANTIGEN CLASS 2; IMMUNOGLOBULIN G; INTERLEUKIN 4; MESSENGER RNA; SCATTER FACTOR;

ANIMAL; B LYMPHOCYTE; BLOOD; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CHRONIC DISEASE; COMPLICATION; DISEASE MODEL; DOWN REGULATION; DRUG EFFECTS; FEMALE; GENETIC TRANSFECTION; GENETICS; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOLOGY; INBRED MOUSE STRAIN; LIVER CIRRHOSIS, BILIARY; LUPUS NEPHRITIS; LYMPHOCYTE COUNT; METABOLISM; MOUSE; OSMOLARITY; PATHOLOGY; PROTEINURIA; SJOGREN'S SYNDROME; SPLEEN; TH2 CELL;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIGENS, CD28; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DNA; DOWN-REGULATION; FEMALE; GRAFT VS HOST DISEASE; HEPATOCYTE GROWTH FACTOR; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-4; LIVER CIRRHOSIS, BILIARY; LUPUS NEPHRITIS; LYMPHOCYTE COUNT; MICE; MICE, INBRED STRAINS; OSMOLAR CONCENTRATION; PROTEINURIA; RNA, MESSENGER; SJOGREN'S SYNDROME; SPLEEN; TH2 CELLS; TRANSFECTION;

EID: 35648975634     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2012     Document Type: Article

References (32)

1. Burlingame RW, Rubin RL, Balderas RS, Theofilopoulos AN: Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J Clin Invest 1993, 91:1687-1696.
2. Desai-Mehta A, Mao C, Rajagopalan S, Robinson T, Datta SK: Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J Clin Invest 1995, 95:531-541.
3. Cohen PL, Litvin DA, Winfield JB: Association between endogeneously activated T cells and immunoglobulin-secreting B cells in patients with active systemic lupus erythematosus. Arthritis Rheum 1982, 25:168-173.
4. Gleichmann E, Pals ST, Rolink AG, Radaszkiewicz T, Gleichmann H: Graft-versus-host reactions: Clues to the etiopathology of a spectrum of immunological diseases. Immunol Today 1984, 5:324-332.
5. Rus VA, Svetic A, Nguyen P, Gausen WC, Via CS: Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease: Regulatory role of donor CD8+ T cells J Immunol 1995, 155:2396-2406.
6. Van Rappard-Van Der Veen FM, Radaszkiewicz T, Teraneo L, Gleichmann E: Attempts at standardization of lupus-like graftvs- host disease: inadvertent repopulation by DBA/2 spleen cells of H-2 different nonirradiated F1 mice. J Immunol 1983, 130:2693-2701.
7. Moser M, Iwasaki T, Shearer GM: Cellular interaction in graftversus-host-induced T cell immune deficiency. Immunol Rev 1985, 88:135-151.
8. Joseph LJ, Iwasaki T, Malek TR, Shearer GM: Interleukin 2 receptor dysfunction in mice undergoing a graft-vs-host reaction. J Immunol 1985, 135:1846-1850.
9. Iwasaki T, Fujiwara H, Iwasaki T, Shearer GM: Loss of proliferative capacity and T cell immune development potential by bone marrow from mice undergoing a graft-vs-host reaction. J Immunol 1986, 137:3100-3108.
10. Via CS, Finkelman FD: Critical role of interleukin-2 in the development of acute graft-versus-host disease. Int Immunol 1993, 5:565-572.
11. Schstov A, Luzina I, Nguyen P, Papadimitriou JC, Handwerger B, Elkon KB, Via CS: Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity. J Clin Invest 2000, 106:R39-47.
12. Via CS, Sharrow SO, Shearer GM: Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of chronic graft-vs-host disease. J Immunol 1987, 139 1840-1849.
13. Via CS, Rus V, Gately MK, Finkelman FD: IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versushost disease. J Immunol 1994, 153:4040-4047.
14. Okamoto I, Kohno K, Tanimoto T, Iwaki K, Ishihara T, Akamatsu S, Ikegami H, Kurimoto M: IL-18 prevents the development of chronic graft-versus-host disease in mice. J Immunol 2000, 164 6067-6074.
15. Kuroiwa T, Kakishita E, Hamano T, Kataoka Y, Seto Y, Iwata N, Kaneda Y, Matsumoto K, Nakamura T, Ueki T, et al.: Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function. J Clin Invest 2001, 107:1365-1373.
16. Imado T, Iwasaki T, Kataoka Y, Kuroiwa T, Hara H, Fujimoto J, Sanoh H: Hepatocyte growth factor preserves graft-versusleukemia effect and T cell reconstitution after marrow transplantation. Blood 2004, 104:1542-1549.
17. Morishita R, Sugimoto T, Aoki M, Kida I, Tomita N, Moriguchi A, Maeda K, Sawa Y, Kaneda Y, Higaki J, et al.: In vivo transfection of cis element "decoy" against nuclear factor-κB binding site prevents myocardial infarction. Nat Med 1997, 3:894-899.
18. Rus V, Svetic A, Nguyen P, Gause WC, Via CS: Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8+ T cells. J Immunol 1995, 155:2396-2406.
19. De Wit D, Van Mechelen M, Zanin C, Doutrelepont JM, Velu T, Gerard C, Abramowicz D, Scheerlinck JP, De Baetselier P, Urbain J, et al.: Preferential activation of Th2 cells in chronic graft-versushost reaction. J Immunol 1993, 150:361-366.
20. Garlisi CG, Pennline KJ, Smith SR, Siegel MI, Umland SP: Cytokine gene expression in mice undergoing chronic graftversus-host disease. Mol Immunol 1993, 30:669-677.
21. Doutrelepont JM, Moser M, Leo O, Abramowicz D, Vanderhaegen ML, Urbain J, Goldman M: Hyper IgE in stimulatory graft-Rersushost disease: role of interleukin-4. Clin Exp Immunol 1991, 83:133-136.
22. Umland SP, Razac S, Nakrebone DK, Seymour BW: Effect of in vivo administration of interferon (IFN)-γ, anti-IFN-γ, or antiinterleukin-4 monoclonal antibodies in chronic autoimmune graft-versus-host disease Clin Immunol Immunopathol 1992, 63:66-73.
23. Gause WC, Chen SJ, Greenwald RJ, Halvorson MJ, Lu P, Zhou XD, Morris SC, Lee KP, June CH, Finkelman FD, et al.: CD28 dependence of T cell differentiation of IL-4 production varies with the particular type 2 immune response. J Immunol 1997, 158:4082-4087.
24. Natesan M, Razi-Wolf Z, Reiser H: Costimulation of IL-4 production by murine B7-1 and B7-2 molecules. J Immunol 1996, 156 2783-2791.
25. Okamoto I, Kohno K, Tanimoto T, Ikegami H, Kurimoto: Development of CD8+ effector T cells is differentially regulated by IL18 and IL12. J Immunol 1999, 162:3202-3211.
26. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K: Immunobiology of dendritic cells. Annu Rev Immunol 2000, 18:767-811.
27. Steinman RM, Nussenzweig MT: Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci USA 2002, 99:351-358.
28. Ferrara JL, Cooke KR, Pan L, Krenger W: The immunopathophysiology of acute graft-versus-host disease. Stem Cells 1996, 14 473-489.
29. Chan GW, Gorgun G, Miller KB, Foss FM: Persistence of host dendritic cells after transplantation is associated with graftversus- host disease Biol Blood Marrow Transplant 2003, 9:170-176.
30. Mehling A, Loser K, Varga G, Metze D, Luger TA, Schwartz T, Grabbe S, Beissert S: Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity. J Exp Med 2001, 194:615-628.
31. Hawiger D, Inaba K, Dorsett Y, Guo K, Mahnke K, Rivera M, Ravetch JV, Steinman RM, Nussenzweig MC: Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001, 194:769-779.
32. Sato K, Yamashita N, Baba M, Matsuyama T: Modified myeloid dendritic cells act as regulatory cells to induce anergic and regulatory T cells Blood 2003, 101:3581-3589.