Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity

Biochemistry

Volumn 47, Issue 1, 2008, Pages 460-472

  Nieland, Thomas J F ^a,b   Shaw, Jared T ^b,c   Jaipuri, Firoz A ^b,c   Duffner, Jay L ^b,c   Koehler, Angela N ^b,c   Banakos, Sotirios ^a   Zannis, Vassilis I ^d   Kirchhausen, Tomas ^e   Krieger, Monty ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITORY ACTIVITY; PHARMACEUTICAL DRUGS; SEMICARBAZONE DERIVATIVES;

CELLS; DRUG PRODUCTS; ENZYME ACTIVITY; LIPOSOMES; MOLECULAR DYNAMICS; SULFUR;

ENZYME INHIBITION;

CHEMICAL COMPOUND; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN RECEPTOR; LIPID; LIPID TRANSPORT BLOCKER; LIPOSOME; MEMBRANE LIPID; OXYGEN 15; RECEPTOR BLOCKING AGENT; SCAVENGER RECEPTOR BI; SULFUR; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHEMICAL ANALYSIS; CONTROLLED STUDY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LIPID TRANSPORT; LIPOPROTEIN METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION;

AMINES; ANTIGENS, CD36; BIOLOGICAL TRANSPORT; CELL LINE; CYCLOPENTANES; HUMANS; LIPID METABOLISM; LIPOPROTEINS, HDL; LIPOSOMES; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, LIPOPROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE; THIOSEMICARBAZONES;

MAMMALIA;

EID: 37849004536     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701277x     Document Type: Article

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