Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1771, Issue 7, 2007, Pages 807-817

  Sahoo, Daisy ^a   Darlington, Yolanda F ^a   Pop, Diana ^a   Williams, David L ^a   Connelly, Margery A ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Detergent; Oligomerization; Scavenger receptor; Selective uptake; SR BI; Tetramer

Indexed keywords

CELL SURFACE RECEPTOR; CHOLESTEROL ESTER; DETERGENT; DIMER; HIGH DENSITY LIPOPROTEIN; MONOMER; SCAVENGER RECEPTOR B; TETRAMER;

ADRENAL GLAND; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CARDIOVASCULAR DISEASE; CELL LINE; CHOLESTEROL TRANSPORT; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; FAST PROTEIN LIQUID CHROMATOGRAPHY; GLYCOSYLATION; HUMAN; HUMAN CELL; LIVER; NONHUMAN; OLIGOMERIZATION; OVARY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEROIDOGENESIS; TESTIS;

ANIMALS; CENTRIFUGATION, DENSITY GRADIENT; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, LIQUID; COS CELLS; CRICETINAE; CRICETULUS; DETERGENTS; DIMERIZATION; HUMANS; IMMUNOPRECIPITATION; MICE; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SCAVENGER RECEPTORS, CLASS B;

EID: 34250028241     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2006.03.003     Document Type: Article

References (48)

1. Miller G.J., and Miller N.E. Plasma high density lipoprotein concentration and the development of ischaemic heart disease. Lancet 1 (1975) 16-19
2. Glomset J.A. The plasma lecithin:cholesterol acyltransferase reaction. J. Lipid Res. 9 (1968) 155-167
3. Lee J.Y., and Parks J.S. ATP-binding cassette transporter AI and its role in HDL formation. Curr. Opin. Lipidol. 16 (2005) 19-25
4. Van Eck M., Pennings M., Hoekstra M., Out R., and Van Berkel T.J. Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis. Curr. Opin. Lipidol. 16 (2005) 307-315
5. Yokoyama S. Assembly of high density lipoprotein by the ABCA1/apolipoprotein pathway. Curr. Opin. Lipidol. 16 (2005) 269-279
6. Wang N., Lan D., Chen W., Matsuura F., and Tall A.R. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 9774-9779
7. Kennedy M.A., Barrera G.C., Nakamura K., Baldan A., Tarr P., Fishbein M.C., Frank J., Francone O.L., and Edwards P.A. ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab. 1 (2005) 121-131
8. Vaughan A.M., and Oram J.F. ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins. J. Biol. Chem. 280 (2005) 30150-30157
9. Rigotti A., Edelman E.R., Seifert P., Iqbal S.N., DeMattos R.B., Temel R.E., Krieger M., and Williams D.L. Regulation by adrenocorticotropic hormone of the in vivo expression of scavenger receptor class B type I (SR-B1), a high density lipoprotein receptor, in steroidogenic cells of the murine adrenal gland. J. Biol. Chem. 271 (1996) 33545-33549
10. Landschulz K.T., Pathak R.K., Rigotti A., Krieger M., and Hobbs H.H. Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat. J. Clin. Invest. 98 (1996) 984-995
11. Reaven E., Nomoto A., Leers-Sucheta S., Temel R., Williams D.L., and Azhar S. Expression and microvillar localization of scavenger receptor, class B, type I (a high density lipoprotein receptor) in luteinized and hormone-desensitized rat ovarian models. Endocrinology 139 (1998) 2847-2856
12. Reaven E., Zhan L., Nomoto A., Leers-Sucheta S., and Azhar S. Expression and microvillar localization of scavenger receptor class B, type I and selective cholesteryl ester uptake in Leydig cells from rat testis. J. Lipid Res. 41 (2000) 343-356
13. Peng Y., Akmentin W., Connelly M.A., Lund-Katz S., Phillips M.C., and Williams D.L. Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein. Mol. Biol. Cell 15 (2004) 384-396
14. Temel R.E., Trigatti B., DeMattos R.B., Azhar S., Krieger M., and Williams D.L. Scavenger receptor B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13600-13605
15. Varban M.L., Rinninger F., Wang N., Fairchild-Huntress V., Dunmore J.H., Fang Q., Gosselin M.L., Dixon K.L., Deeds J.D., Acton S.L., Tall A.R., and Huszar D. Targeted mutation reveals a central role of SR-BI in hepatic selective uptake of high density lipoprotein cholesterol. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 4619-4624
16. Kozarsky K.F., Donahee M.H., Rigotti A., Iqbal S.N., Edelman E.R., and Krieger M. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature 387 (1997) 414-417
17. Rigotti A., Trigatti B.L., Penman M., Rayburn H., Herz J., and Krieger M. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 12610-12615
18. Ji Y., Wang N., Ramakrishnan R., Sehayek E., Huszar D., Breslow J.L., and Tall A.R. Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. J. Biol. Chem. 274 (1999) 33398-33402
19. Covey S.D., Krieger M., Wang W., Penman M., and Trigatti B.L. Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells. [see comment]. Arterioscler. Thromb. Vasc. Biol. 23 (2003) 1589-1594
20. Van Eck M., Bos I.S., Hildebrand R.B., Van Rij B.T., and Van Berkel T.J. Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development. Am. J. Pathol. 165 (2004) 785-794
21. Zhang W., Yancey P.G., Su Y.R., Babaev V.R., Zhang Y., Fazio S., and Linton M.F. Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 108 (2003) 2258-2263
22. Rodrigueza W.V., Thuahnai S.T., Temel R.E., Lund-Katz S., Phillips M.C., and Williams D.L. Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells. J. Biol. Chem. 274 (1999) 20344-20350
23. Liu B., and Krieger M. Highly purified scavenger receptor class B, type I reconstituted into phosphatidylcholine/cholesterol liposomes mediates high affinity high density lipoprotein binding and selective lipid uptake. J. Biol. Chem. 277 (2002) 34125-34135
24. Azhar S., Nomoto A., and Reaven E. Hormonal regulation of adrenal microvillar channel formation. J. Lipid Res. 43 (2002) 861-871
25. Silver D.L. A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver. J. Biol. Chem. 277 (2002) 34042-34047
26. Reaven E., Cortez Y., Leers-Sucheta S., Nomoto A., and Azhar S. Dimerization of the scavenger receptor class B type I (SR-BI): formation, function and localization in diverse cells and tissues. J. Lipid Res. 45 (2004) 513-528
27. Connelly M.A., Klein S.M., Azhar S., Abumrad N.A., and Williams D.L. Comparison of class B scavenger receptors, CD36 and SR-BI, shows that both receptors mediate HDL-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake. J. Biol. Chem. 274 (1999) 41-47
28. Connelly M.A., de la Llera-Moya M., Monzo P., Yancey P., Drazul D., Stoudt G., Fournier N., Klein S.M., Rothblat G.H., and Williams D.L. Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI) are localized to the extracellular receptor domain. Biochemistry 40 (2001) 5249-5259
29. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
30. Nieland T.J., Penman M., Dori L., Krieger M., and Kirchhausen T. Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 15422-15427
31. Gilboa L., Wells R.G., Lodish H.F., and Henis Y.I. Oligomeric structure of type I and type II transforming growth factor beta receptors: homodimers form in the ER and persist at the plasma membrane. J. Cell Biol. 140 (1998) 767-777
32. Schagger H., and von Jagow G. Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form. Anal. Biochem. 199 (1991) 223-231
33. Schagger H., Cramer W.A., and von Jagow G. Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal. Biochem. 217 (1994) 220-230
34. Kilic F., and Rudnick G. Oligomerization of serotonin transporter and its functional consequences. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 3106-3111
35. Richards M.R., Listenberger L.L., Kelly A.A., Lewis S.E., Ory D.S., and Schaffer J.E. Oligomerization of the murine fatty acid transport protein 1 (FATP1). J. Biol. Chem. 278 (2003) 10477-10483
36. 2A and β1-adrenergic receptors. J. Biol. Chem. 278 (2003) 10770-10777
37. Quirk J.C., and Reinhart P.H. Identification of a novel tetramerization domain in large conductance Kca channels. Neuron 32 (2001) 13-23
38. Van Aken T., Foxall-Van Aken S., Castleman S., and Ferguson-Miller S. Alkyl glucoside detergents-synthesis and applications to the study of membrane proteins. Methods Enzymol. 125 (1986) 27-35
39. 2+-ATPase from sarcoplasmic reticulum. J. Biol. Chem. 264 (1989) 4907-4915
40. Failer B.U., Aschrafi A., Schmalzing G., and Zimmermann H. Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes. Eur. J. Biochem. 270 (2003) 1802-1809
41. 3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. EMBO J. 17 (1998) 3016-3028
42. Richie-Jannetta R., Francis S.H., and Corbin J.D. Dimerization of cGMP-dependent protein kinase Ibeta is mediated by an extensive amino-terminal leucine zipper motif, and dimerization modulates enzyme function. J. Biol. Chem. 278 (2003) 50070-50079
43. Rishi V., Gal J., Krylov D., Fridriksson J., Boysen M.S., Mandrup S., and Vinson C. SREBP-1 dimerization specificity maps to both the helix-loop-helix and leucine zipper domains: use of a dominant negative. J. Biol. Chem. 279 (2004) 11863-11874
44. Kanki H., Kupershmidt S., Yang T., Wells S., and Roden D.M. A structural requirement for processing the cardiac K+ channel KCNQ1. J. Biol. Chem. 279 (2004) 33976-33983
45. Russ W.P., and Engelman D.M. The GxxxG motif: a framework for transmembrane helix-helix association. J. Mol. Biol. 296 (2000) 911-919
46. Curran A.R., and Engelman D.M. Sequence motifs, polar interactions and conformational changes in helical membrane proteins. Curr. Opin. Struct. Biol. 13 (2003) 412-417
47. Johnson M.S., Svensson P.A., Helou K., Billig H., Levan G., Carlsson L.M., and Carlsson B. Characterization and chromosomal localization of rat scavenger receptor class B type I, a high density lipoprotein receptor with a putative leucine zipper domain and peroxisomal targeting sequence. Endocrinology 139 (1998) 72-80
48. Parathath S., Sahoo D., Darlington Y.F., Peng Y., Collins H.L., Rothblat G.H., Williams D.L., and Connelly M.A. Glycine 420 near the C-terminal transmembrane domain of SR-BI Is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester. J. Biol. Chem. 279 (2004) 24976-24985