Effects of selective inhibition of N-acetylated-α-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasks

European Journal of Pharmacology

Volumn 579, Issue 1-3, 2008, Pages 202-207

  Łukawski, Krzysztof ^a,b   Kamiński, Rafał M ^b   Czuczwar, Stanisław J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

(Mice); NAALADase inhibition; Passive avoidance; Y maze

Indexed keywords

2 (PHOSPHONOMETHYL)PENTANEDIOIC ACID; DIZOCILPINE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; GLUTAMIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHRONOPHARMACOLOGY; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; ELECTRONICS; ENZYME INHIBITION; ENZYME MECHANISM; FEMALE; LATENT PERIOD; LEARNING; LOCOMOTION; LONG TERM MEMORY; MAZE TEST; MEMORY; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RECALL; SINGLE DRUG DOSE; SPATIAL MEMORY; TASK PERFORMANCE; TRAINING; WORKING MEMORY;

ANIMALS; AVOIDANCE LEARNING; DIPEPTIDES; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTAMATE CARBOXYPEPTIDASE II; MAZE LEARNING; MEMORY; MICE; MOTOR ACTIVITY; ORGANOPHOSPHORUS COMPOUNDS;

EID: 37549070398     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.10.032     Document Type: Article

References (25)

1. Adriani W., Felici A., Sargolini F., Roullet P., Usiello A., Oliverio A., and Mele A. N-methyl-d-aspartate and dopamine receptor involvement in the modulation of locomotor activity and memory processes. Exp. Brain Res. 123 (1998) 52-59
2. Aultman J.M., and Moghaddam B. Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task. Psychopharmacology 153 (2001) 353-364
3. Benvenga M.J., and Spaulding T.C. Amnesic effect of the novel anticonvulsant MK-801. Pharmacol. Biochem. Behav. 30 (1988) 205-207
4. 2 receptor-transfected cell membranes. Br. J. Pharmacol. 123 (1998) 497-504
5. Danysz W., Essmann U., Bresink I., and Wilke R. Glutamate antagonists have different effects on spontaneous locomotor activity in rats. Pharmacol. Biochem. Behav. 48 (1994) 111-118
6. Ginski M., and Witkin J.M. Sensitive and rapid behavioral differentiation of N-methyl-d-aspartate receptor antagonists. Psychopharmacology 114 (1994) 573-582
7. Higgins G.A., Ballard T.M., Kew J.N.C., Richards J.G., Kemp J.A., Adam G., Woltering T., Nakanishi S., and Mutel V. Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent. Neuropharmacology 46 (2004) 907-917
8. Jackson P.F., Cole D.C., Slusher B.S., Stetz S.L., Ross L.E., Donzanti B.A., and Trainor D.A. Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated-α-linked acidic dipeptidase. J. Med. Chem. 39 (1996) 619-622
9. Lea IV P.M., Wroblewska B., Sarvey J.M., and Neale J.H. Beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. J. Neurophysiol. 85 (2001) 1097-1106
10. Maurice T., Su T.-P., Parish D.W., Nabeshima T., and Privat A. PRE-084, a σ selective PCP derivative, attenuates MK-801-induced impairment of learning in mice. Pharmacol. Biochem. Behav 49 (1994) 859-869
11. Myhrer T. Neurotransmitter systems involved in learning and memory in the rat: a meta-analysis based on studies of four behavioral tasks. Brain Res. Rev. 41 (2003) 268-287
12. Parada-Turska J., and Turski W.A. Excitatory amino acid antagonists and memory: effect of drugs acting at N-methyl-d-aspartate receptors in learning and memory tasks. Neuropharmacology 29 (1990) 1111-1116
13. Parsons C.G., Danysz W., and Quack G. Glutamate in CNS disorders as a target for drug development: an update. Drug News Perspect. 11 (1998) 523-569
14. Popik P., Kozela E., Wróbel M., Wozniak K.M., and Slusher B.S. Morphine tolerance and reward but not expression of morphine dependence are inhibited by the selective glutamate carboxypeptidase II (GCP II, NAALADase) inhibitor, 2-PMPA. Neuropsychopharmacology 28 (2003) 457-467
15. Sarter M., Bodewitz G., and Stephens D.N. Attenuation of scopolamine-induced impairment of spontaneous alternation behavior by antagonist but not inverse agonist and agonist beta-carbolines. Psychopharmacology 94 (1988) 491-495
16. Sarvey J.M., Burgard E.C., and Decker G. Long-term potentiation: studies in the hippocampal slice. J. Neurosci. Methods 28 (1989) 109-124
17. Schweitzer C., Kratzeisen C., Adam G., Lundstrom K., Malherbe P., Ohresser S., Stadler H., Wichmann J., Woltering T., and Mutel V. Characterization of LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using Semliki Forest virus vectors. Neuropharmacology 39 (2000) 1700-1706
18. 3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain. Neurochem. Int. 38 (2001) 53-62
19. Slusher B.S., Thomas A., Paul M., Schad C.A., and Ashby C.R. Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N-acetylated-α-linked-acidic dipeptidase (NAALADase). Synapse 41 (2001) 22-28
20. Slusher B.S., Vornov J.J., Thomas A.G., Hurn P.D., Harukuni I., Bhardwaj A., Traystman J., Robinson M.B., Britton P., May Lu X.-C., Tortella F.C., Wozniak K.M., Yudkoff M., Potter B.M., and Jackson P.F. Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury. Nat. Med. 5 (1999) 1396-1402
21. Spinelli S., Ballard T., Gatti-McArthur S., Richards G.J., Kapps M., Woltering T., Wichmann J., Stadler H., Feldon J., and Pryce C.R. Effects of the mGluR2/3 agonist LY354740 on computerized tasks of attention and working memory in marmoset monkeys. Psychopharmacology 179 (2005) 292-302
22. Venault P., Chapouthier G., Prado de Carvalho L., Simiand J., Morre M., Dodd R.H., and Rossier J. Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks. Nature 321 (1986) 864-866
23. Witkin J.M., Gasior M., Schad C., Zapata A., Shippenberg T., Hartman T., and Slusher B.S. NAALADase (CGP II) inhibition prevents cocaine-kindled seizures. Neuropharmacology 43 (2002) 348-356
24. Wong E.H.F., Kemp J.A., Priestley T., Knight A.R., Woodruff G.N., and Iverson L.L. The anticonvulsant MK-801 is a potent N-methyl-d-aspartate antagonist. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 7104-7108
25. Wroblewska B., Wroblewski J.T., Pshenichkin S., Surin A., Sullivan S.E., and Neale J.H. NAAG selectively activates mGluR3 receptors in transfected cells. J. Neurochem. 69 (1997) 174-181