NAALADase (GCP II) inhibition prevents cocaine-kindled seizures

Neuropharmacology

Volumn 43, Issue 3, 2002, Pages 348-356

  Witkin, Jeffrey M ^a   Gasior, Maciej ^a   Schad, Christina ^b   Zapata, Agustin ^a   Shippenberg, Toni ^a   Hartman, Theresa ^b   Slusher, Barbara S ^b  

^a NIDA Addiction Research Center   (United States)

^b GUILFORD PHARMACEUTICALS INC   (United States)

Author keywords

Cocaine; Mice; NAAG; NAALADase inhibition; Seizure kindling

Indexed keywords

2 (PHOSPHONOMETHYL)PENTANEDIOIC ACID; BICUCULLINE; COCAINE; ENZYME INHIBITOR; GAMMA GLUTAMYL HYDROLASE; N METHYLASPARTIC ACID; PENTETRAZOLE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; ELECTRIC SHOCK; ENZYME INHIBITION; INCIDENCE; KINDLING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SEIZURE SUSCEPTIBILITY; SEIZURE THRESHOLD; SENSITIZATION;

ANIMALS; ANTICONVULSANTS; BEHAVIOR, ANIMAL; CARBOXYPEPTIDASES; COCAINE; CONVULSANTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY, TONIC-CLONIC; GLUTAMATE CARBOXYPEPTIDASE II; KINDLING, NEUROLOGIC; MALE; MICE; ORGANOPHOSPHORUS COMPOUNDS; SEIZURES;

EID: 0036710910     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00124-7     Document Type: Article

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