-
1
-
-
0002775591
-
Noncancer risk assessment: A probabilistic alternative to current practice
-
Baird, S. J. S., Cohen, J. T., Graham, J. D., Shlyakhter, A. I., and Evans, J. S. 1996. Noncancer risk assessment: a probabilistic alternative to current practice. Hum. Ecol. Risk Assess. 2:78-99.
-
(1996)
Hum. Ecol. Risk Assess
, vol.2
, pp. 78-99
-
-
Baird, S.J.S.1
Cohen, J.T.2
Graham, J.D.3
Shlyakhter, A.I.4
Evans, J.S.5
-
2
-
-
0026017378
-
Bronchial responsiveness in a Norwegian community
-
Bakke, S., Baste, V., and Gulsvik, A. 1991. Bronchial responsiveness in a Norwegian community. Am. Rev. Respir. Dis. 143:317-322.
-
(1991)
Am. Rev. Respir. Dis
, vol.143
, pp. 317-322
-
-
Bakke, S.1
Baste, V.2
Gulsvik, A.3
-
3
-
-
37549027507
-
-
Balmes, J. R., Aris, R. M., Chen, L. L., Scannell, C., Tager, I. B., Finkbeiner, W., Christian, D., Keller, T., Hearne, P. Q., Ferrando, R., and Welch, B. 1997. Airway inflammation and responsiveness to ozone in normal and asthmatic subjects. In Effects of ozone on normal and potentially sensitive subjects. Research Report Number 78. Cambridge, MA: Health Effects Institute, pp. 81-99.
-
Balmes, J. R., Aris, R. M., Chen, L. L., Scannell, C., Tager, I. B., Finkbeiner, W., Christian, D., Keller, T., Hearne, P. Q., Ferrando, R., and Welch, B. 1997. Airway inflammation and responsiveness to ozone in normal and asthmatic subjects. In Effects of ozone on normal and potentially sensitive subjects. Research Report Number 78. Cambridge, MA: Health Effects Institute, pp. 81-99.
-
-
-
-
4
-
-
84886549468
-
Supplemental guidance for assessing susceptibility from early-life exposure to carcinogens. EPA/630/R-03/003F
-
Washington, DC: U.S. EPA, accessed December 19
-
Barton, H., Cogliano, J., Firestone, M. P., Flowers, L., Setzer, R. W., Valcovic, L., and Woodruff, T. 2005. Supplemental guidance for assessing susceptibility from early-life exposure to carcinogens. EPA/630/R-03/003F. Risk Assessment Forum. Washington, DC: U.S. EPA. http://cfpub.epa.gov/ncea/cfm/ recordisplay.cfm?deid=160003 (accessed December 19, 2006).
-
(2005)
Risk Assessment Forum
-
-
Barton, H.1
Cogliano, J.2
Firestone, M.P.3
Flowers, L.4
Setzer, R.W.5
Valcovic, L.6
Woodruff, T.7
-
5
-
-
0043092167
-
Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling
-
Clewell, R. A., Merrill, E. A., Yu, K. O., Mahle, D. A., Sterner, T. R., Fisher, J. W., and Gearhart, J. M. 2003. Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling. Toxicol. Sci. 74:416-436.
-
(2003)
Toxicol. Sci
, vol.74
, pp. 416-436
-
-
Clewell, R.A.1
Merrill, E.A.2
Yu, K.O.3
Mahle, D.A.4
Sterner, T.R.5
Fisher, J.W.6
Gearhart, J.M.7
-
6
-
-
1042292061
-
A framework for assessing risks to children from exposure to environmental agents
-
Daston, G., Faustman, E., Ginsberg, G., Fenner-Crisp, P., Olin, S., Sonawane, B.R., Bruckner, J., Breslin, W., and McLaughlin, T. J. 2004. A framework for assessing risks to children from exposure to environmental agents. Environ. Health Perspecdt. 112:238-256. http://ehp.niehs.nih.gov/ members/2003/6182/6182.html
-
(2004)
Environ. Health Perspecdt
, vol.112
, pp. 238-256
-
-
Daston, G.1
Faustman, E.2
Ginsberg, G.3
Fenner-Crisp, P.4
Olin, S.5
Sonawane, B.R.6
Bruckner, J.7
Breslin, W.8
McLaughlin, T.J.9
-
7
-
-
26944449329
-
The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans
-
Dorne, J. L. C. M., and Renwick, A. G. 2005. The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans. Toxicol. Sci. 86:20-26.
-
(2005)
Toxicol. Sci
, vol.86
, pp. 20-26
-
-
Dorne, J.L.C.M.1
Renwick, A.G.2
-
8
-
-
0034993738
-
Uncertainty factors for chemical risk assessment: Human variability in the pharmacokinetics of CYP1A2 probe substrates
-
Dorne, J. L. C. M., Walton, K., and Renwick, A. G. 2001. Uncertainty factors for chemical risk assessment: human variability in the pharmacokinetics of CYP1A2 probe substrates. Food Chem. Toxicol. 39:681-696.
-
(2001)
Food Chem. Toxicol
, vol.39
, pp. 681-696
-
-
Dorne, J.L.C.M.1
Walton, K.2
Renwick, A.G.3
-
9
-
-
22044431800
-
Accounting for missing data in noncancer risk assessment
-
Evans, J. S., and Baird, S. J. S. 1998. Accounting for missing data in noncancer risk assessment. Hum. Ecol. Risk Assess. 4:291-317.
-
(1998)
Hum. Ecol. Risk Assess
, vol.4
, pp. 291-317
-
-
Evans, J.S.1
Baird, S.J.S.2
-
10
-
-
0027424629
-
Physiologically based toxicokinetic modeling of 1,3-butadiene lung metabolism in mice becomes more important at low doses
-
Evelo, C. T. A., Oostendorp, J. G. M., ten Berge, W. F., and Borm, P. J. A. 1993. Physiologically based toxicokinetic modeling of 1,3-butadiene lung metabolism in mice becomes more important at low doses. Environ. Health Perspect. 101:496-502.
-
(1993)
Environ. Health Perspect
, vol.101
, pp. 496-502
-
-
Evelo, C.T.A.1
Oostendorp, J.G.M.2
ten Berge, W.F.3
Borm, P.J.A.4
-
11
-
-
0010995012
-
Protection of children from environmental health risks and safety risks
-
Executive Order 13045
-
Executive Order 13045. 1997. Protection of children from environmental health risks and safety risks. Fed. Reg. 62(78):19883-19888. http://www.epa.gov/fedrgstr/eo/eo13045.htm
-
(1997)
Fed. Reg
, vol.62
, Issue.78
, pp. 19883-19888
-
-
-
12
-
-
0024524118
-
Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues
-
Gargas, M. L., Burgess, R. J., Voisard, D. E., Cason, G. H., and Andersen, M. E. 1989. Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 98:87-99.
-
(1989)
Toxicol. Appl. Pharmacol
, vol.98
, pp. 87-99
-
-
Gargas, M.L.1
Burgess, R.J.2
Voisard, D.E.3
Cason, G.H.4
Andersen, M.E.5
-
13
-
-
0346993717
-
A distributed-parameter model for formaldehyde uptake and disposition in the rat nasal lining
-
Georgieva, A. V., Kimbell, J. S., and Schlosser, P. M. 2003. A distributed-parameter model for formaldehyde uptake and disposition in the rat nasal lining. Inhal. Toxicol. 15:1435-1463.
-
(2003)
Inhal. Toxicol
, vol.15
, pp. 1435-1463
-
-
Georgieva, A.V.1
Kimbell, J.S.2
Schlosser, P.M.3
-
14
-
-
17444374921
-
Review and analysis of inhalation dosimetry methods for application to children's risk assessment
-
Ginsberg, G. L., Foos, B. P., and Firesetone, M. P. 2005a. Review and analysis of inhalation dosimetry methods for application to children's risk assessment. J. Toxicol. Environ. Health A 68:573-615.
-
(2005)
J. Toxicol. Environ. Health A
, vol.68
, pp. 573-615
-
-
Ginsberg, G.L.1
Foos, B.P.2
Firesetone, M.P.3
-
15
-
-
25844458497
-
Pharmacokinetic and pharmacodynamic factors that can affect sensitivity to neurotoxic sequelae in the elderly
-
Ginsberg, G., Hattis, D., Russ, A., and Sonawane, B. 2005b. Pharmacokinetic and pharmacodynamic factors that can affect sensitivity to neurotoxic sequelae in the elderly. Environ. Health Perspect. 113:1243-1249.
-
(2005)
Environ. Health Perspect
, vol.113
, pp. 1243-1249
-
-
Ginsberg, G.1
Hattis, D.2
Russ, A.3
Sonawane, B.4
-
16
-
-
0036211903
-
Evaluation of child/adult pharmacokinetic differences form a database derived from the therapeutic drug literature
-
Ginsberg, G., Hattis, D., Sonawane, B., Russ, A., Banati, P., Kozlak, M., Smolenski, S., and Goble, R. 2002. Evaluation of child/adult pharmacokinetic differences form a database derived from the therapeutic drug literature. Toxicol. Sci. 66:185-200.
-
(2002)
Toxicol. Sci
, vol.66
, pp. 185-200
-
-
Ginsberg, G.1
Hattis, D.2
Sonawane, B.3
Russ, A.4
Banati, P.5
Kozlak, M.6
Smolenski, S.7
Goble, R.8
-
17
-
-
1042304192
-
Incorporating children's toxicokinetics into a risk framework
-
Ginsberg, G.I., Slikker, W. Jr., Bruckner, J., and Sonawane, B. 2004. Incorporating children's toxicokinetics into a risk framework. Environ. Health Perspect. 112:272-283. http://ehp.niehs.nih.gov/members/2003/6013/ 6013.html
-
(2004)
Environ. Health Perspect
, vol.112
, pp. 272-283
-
-
Ginsberg, G.I.1
Slikker Jr., W.2
Bruckner, J.3
Sonawane, B.4
-
18
-
-
0034874732
-
A PBPK modeling-based approach to account for interactions in the health risk assessment of chemical mixtures
-
Haddad, S., Beliveau, M., Tardif, R., and Krishnan, K. 2001. A PBPK modeling-based approach to account for interactions in the health risk assessment of chemical mixtures. Toxicol. Sci. 63:125-131.
-
(2001)
Toxicol. Sci
, vol.63
, pp. 125-131
-
-
Haddad, S.1
Beliveau, M.2
Tardif, R.3
Krishnan, K.4
-
19
-
-
0031710611
-
Effect of exposure to low levels of ozone on the response to inhaled allergen in allergic asthmatic patients
-
Hanania, N. A., Tarlo, S. M., Silverman, F., Urch, B., Senathirajah, N., Zamel, N., and Corey, P. 1998. Effect of exposure to low levels of ozone on the response to inhaled allergen in allergic asthmatic patients. Chest 114:752-756.
-
(1998)
Chest
, vol.114
, pp. 752-756
-
-
Hanania, N.A.1
Tarlo, S.M.2
Silverman, F.3
Urch, B.4
Senathirajah, N.5
Zamel, N.6
Corey, P.7
-
20
-
-
45349085332
-
The conception of variability in risk analyses - Developments since 1980
-
eds. T. McDaniels and M. Small, pp, Cambridge, MA: Cambridge University Press
-
Hattis, D. 2003. The conception of variability in risk analyses - Developments since 1980. In Risk analysis and society in the 21st century: An interdisciplinary characterization of the field, eds. T. McDaniels and M. Small, pp. 15-45. Cambridge, MA: Cambridge University Press.
-
(2003)
Risk analysis and society in the 21st century: An interdisciplinary characterization of the field
, pp. 15-45
-
-
Hattis, D.1
-
21
-
-
37549006807
-
Distributional analyses for children's inhalation risk assessments
-
Hattis, D. 2007. Distributional analyses for children's inhalation risk assessments. J. Toxicol. Environ. Health A, 71:218-226.
-
(2007)
J. Toxicol. Environ. Health A
, vol.71
, pp. 218-226
-
-
Hattis, D.1
-
22
-
-
0036386331
-
A straw man proposal for a quantitative definition of the RfD
-
Hattis, D., Baird, S., and Goble, R., 2002. A straw man proposal for a quantitative definition of the RfD. Drug Chem. Toxicol. 25:403-436.
-
(2002)
Drug Chem. Toxicol
, vol.25
, pp. 403-436
-
-
Hattis, D.1
Baird, S.2
Goble, R.3
-
23
-
-
0033178105
-
Human interindividual variability in parameters related to health risks
-
Hattis, D., Banati, P., Goble, R., and Burmaster, D. 1999. Human interindividual variability in parameters related to health risks. Risk Anal. 19:705-720.
-
(1999)
Risk Anal
, vol.19
, pp. 705-720
-
-
Hattis, D.1
Banati, P.2
Goble, R.3
Burmaster, D.4
-
24
-
-
0028149336
-
Assessment of variability and uncertainty distributions for practical risk analyses
-
Hattis, D., and Burmaster, D. E. 1994. Assessment of variability and uncertainty distributions for practical risk analyses. Risk Anal. 14:713-730.
-
(1994)
Risk Anal
, vol.14
, pp. 713-730
-
-
Hattis, D.1
Burmaster, D.E.2
-
25
-
-
0242501567
-
Differences in pharmacokinetics between children and adults. II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling
-
Hattis, D., Ginsberg, G, Sonawane, B., Smolenski, S., Russ, A., Kozlak, M., and Goble, R. 2003. Differences in pharmacokinetics between children and adults. II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling. Risk Anal. 23:117-142.
-
(2003)
Risk Anal
, vol.23
, pp. 117-142
-
-
Hattis, D.1
Ginsberg, G.2
Sonawane, B.3
Smolenski, S.4
Russ, A.5
Kozlak, M.6
Goble, R.7
-
26
-
-
18044376877
-
Age-related differences in susceptibility to carcinogenesis. II. Approaches for application and uncertainty analyses for individual genetically acting carcinogens
-
Hattis, D., Goble, R., and Chu, M. 2005. Age-related differences in susceptibility to carcinogenesis. II. Approaches for application and uncertainty analyses for individual genetically acting carcinogens. Environ. Health Perspect. 113:509-516.
-
(2005)
Environ. Health Perspect
, vol.113
, pp. 509-516
-
-
Hattis, D.1
Goble, R.2
Chu, M.3
-
27
-
-
4344679454
-
Age-related differences in susceptibility to carcinogenesis - A quantitative analysis of empirical animal bioassay data
-
Hattis, D., Goble, R., Russ, A., Chu, M, and Ericson, J. 2004. Age-related differences in susceptibility to carcinogenesis - A quantitative analysis of empirical animal bioassay data. Environ. Health Perspect. 112:1152-1158.
-
(2004)
Environ. Health Perspect
, vol.112
, pp. 1152-1158
-
-
Hattis, D.1
Goble, R.2
Russ, A.3
Chu, M.4
Ericson, J.5
-
28
-
-
37549009802
-
-
Hattis, D., and Lynch, M. K. 2006. Interspecies differences and human interindividual variability in tissue-level pharmacokinetic parameters. Task 3 - Final report - Description and analyses of the databases. Report by Clark University to the U.S. Environmental Protection Agency under Purchase Order No. EP05W002147. http://www2.clarku.edu/faculty/dhattis (accessed December 19, 2006).
-
Hattis, D., and Lynch, M. K. 2006. Interspecies differences and human interindividual variability in tissue-level pharmacokinetic parameters. Task 3 - Final report - Description and analyses of the databases. Report by Clark University to the U.S. Environmental Protection Agency under Purchase Order No. EP05W002147. http://www2.clarku.edu/faculty/dhattis (accessed December 19, 2006).
-
-
-
-
29
-
-
85122908106
-
Empirically observed distributions of pharmacokinetic and pharmacodynamic variability in humans - Implications for the derivation of single point component uncertainty factors providing equivalent protection as existing RfDs
-
eds. J. C. Lipscomb and E. V. Ohanian, pp, New York: Marcel Dekker
-
Hattis, D., and Lynch, M. K. 2007. Empirically observed distributions of pharmacokinetic and pharmacodynamic variability in humans - Implications for the derivation of single point component uncertainty factors providing equivalent protection as existing RfDs. In Toxicokinetics in risk assessment, eds. J. C. Lipscomb and E. V. Ohanian, pp. 69-93. New York: Marcel Dekker.
-
(2007)
Toxicokinetics in risk assessment
, pp. 69-93
-
-
Hattis, D.1
Lynch, M.K.2
-
30
-
-
0035703460
-
Human interindividual variability in susceptibility to airborne particles
-
Hattis, D., Russ, A., Goble, R., Banati, P., and Chu, M. 2001. Human interindividual variability in susceptibility to airborne particles. Risk Anal. 21:585-599.
-
(2001)
Risk Anal
, vol.21
, pp. 585-599
-
-
Hattis, D.1
Russ, A.2
Goble, R.3
Banati, P.4
Chu, M.5
-
31
-
-
37549059822
-
-
Hattis, D., and Russ, A. 2004. Role of dosimetric scaling and species extrapolation in evaluating risks across life stages. II. Pharmacokinetic dosimetric considerations in old age. Final report to the U.S. Environmental Protection Agency under RFQ no. DC-03-0000. Washington, DC: U.S. EPA.
-
Hattis, D., and Russ, A. 2004. Role of dosimetric scaling and species extrapolation in evaluating risks across life stages. II. Pharmacokinetic dosimetric considerations in old age. Final report to the U.S. Environmental Protection Agency under RFQ no. DC-03-0000. Washington, DC: U.S. EPA.
-
-
-
-
33
-
-
0035172387
-
Dosimetry modeling of inhaled formaldehyde: Comparisons of local flux predictions in the rat, monkey, and human nasal passages
-
Kimbell, J. S., Subramaniam, R. P., Gross, E. A., Schlosser, P. M., and Morgan, K. T. 2001a. Dosimetry modeling of inhaled formaldehyde: Comparisons of local flux predictions in the rat, monkey, and human nasal passages. Toxicol. Sci. 64:100-110.
-
(2001)
Toxicol. Sci
, vol.64
, pp. 100-110
-
-
Kimbell, J.S.1
Subramaniam, R.P.2
Gross, E.A.3
Schlosser, P.M.4
Morgan, K.T.5
-
34
-
-
0035158910
-
Dosimetry modeling of inhaled formaldehyde: Binning nasal flux predictions for quantitative risk assessment
-
Kimbell, J. S., Overton, J. H., Subramaniam, R. P., Schlosser, P. M., Morgan, K. T., Conolly, R. B., and Miller, F. J. 2001b. Dosimetry modeling of inhaled formaldehyde: Binning nasal flux predictions for quantitative risk assessment. Toxicol. Sci. 64:111-121.
-
(2001)
Toxicol. Sci
, vol.64
, pp. 111-121
-
-
Kimbell, J.S.1
Overton, J.H.2
Subramaniam, R.P.3
Schlosser, P.M.4
Morgan, K.T.5
Conolly, R.B.6
Miller, F.J.7
-
35
-
-
8444235339
-
Children's susceptibility to chemicals: A review by developmental stage
-
Makri, A., Goveia, M., Balbus, J., and Parkin, B. 2004. Children's susceptibility to chemicals: A review by developmental stage. J. Toxicol. Environ. Health B 6:417-435.
-
(2004)
J. Toxicol. Environ. Health B
, vol.6
, pp. 417-435
-
-
Makri, A.1
Goveia, M.2
Balbus, J.3
Parkin, B.4
-
36
-
-
0001864615
-
Comparative response in carcinogenesis bioassay as a function of age at first exposure
-
eds. P. Guzelian, C. J. Henry, and S. S. Olin, pp, Washington, DC: ILSI Press
-
McConnell, E. E. 1992. Comparative response in carcinogenesis bioassay as a function of age at first exposure. In Similarities and difference between children and adults: Implications for risk assessment, eds. P. Guzelian, C. J. Henry, and S. S. Olin, pp. 66-78. Washington, DC: ILSI Press.
-
(1992)
Similarities and difference between children and adults: Implications for risk assessment
, pp. 66-78
-
-
McConnell, E.E.1
-
37
-
-
0003655906
-
-
National Research Council, National Research Council. Washington, DC: National Academy Press
-
National Research Council. 1993. Pesticides in the diets of infants and children. National Research Council. Washington, DC: National Academy Press. http://www.nap.edu/catalog/2126.html
-
(1993)
Pesticides in the diets of infants and children
-
-
-
38
-
-
0023631781
-
Analysis of dose-response curves to methacholine: An approach suitable for population studies
-
O'Connor, G., Sparrow, D. Taylor, D., Segal, M., and Weiss, S. 1987. Analysis of dose-response curves to methacholine: An approach suitable for population studies. Am. Rev. Respir. Dis. 136:1412-1417.
-
(1987)
Am. Rev. Respir. Dis
, vol.136
, pp. 1412-1417
-
-
O'Connor, G.1
Sparrow, D.2
Taylor, D.3
Segal, M.4
Weiss, S.5
-
40
-
-
0141740530
-
Workshop to develop a framework for assessing risks to children from exposure to environmental agents
-
Olin, S. S., and Sonawane, B.R. 2003. Workshop to develop a framework for assessing risks to children from exposure to environmental agents. Environ. Health Perspect. 111:1524-1526. http://ehp.niehs.nih.gov/members/2003/6183/ 6183.html
-
(2003)
Environ. Health Perspect
, vol.111
, pp. 1524-1526
-
-
Olin, S.S.1
Sonawane, B.R.2
-
41
-
-
0029017089
-
Distribution of bronchial responsiveness in a general population: Effect of sex, age, smoking, and level of pulmonary function
-
Paoletti, P., Carrozzi, L., Viegi, G., Modena, P., Ballerin, L., Di Pede, F., Grado, L., Baldacci, S., Pedreschi, M., Vellutini, M., Paggiaro, P., Mammini, U., Fabbri, L., and Giuntini, C. 1995. Distribution of bronchial responsiveness in a general population: Effect of sex, age, smoking, and level of pulmonary function. Am. J. Respir. Crit. Care Med. 151:1770-1777.
-
(1995)
Am. J. Respir. Crit. Care Med
, vol.151
, pp. 1770-1777
-
-
Paoletti, P.1
Carrozzi, L.2
Viegi, G.3
Modena, P.4
Ballerin, L.5
Di Pede, F.6
Grado, L.7
Baldacci, S.8
Pedreschi, M.9
Vellutini, M.10
Paggiaro, P.11
Mammini, U.12
Fabbri, L.13
Giuntini, C.14
-
42
-
-
0037436798
-
Physiological modeling of agespecific changes in the pharmacokinetics of organic chemicals in children
-
Price, K., Haddad, S., and Krishnan, K. 2003. Physiological modeling of agespecific changes in the pharmacokinetics of organic chemicals in children. J. Toxicol. Environ. Health A 66:417-433.
-
(2003)
J. Toxicol. Environ. Health A
, vol.66
, pp. 417-433
-
-
Price, K.1
Haddad, S.2
Krishnan, K.3
-
43
-
-
0031934439
-
Toxicokinetics in infants and children in relation to the ADI and TDI
-
Renwick, A. G. 1998. Toxicokinetics in infants and children in relation to the ADI and TDI. Food Addit. Contam. 15(Suppl.):17-35.
-
(1998)
Food Addit. Contam
, vol.15
, Issue.SUPPL.
, pp. 17-35
-
-
Renwick, A.G.1
-
44
-
-
0032438553
-
Empirical scaling of single oral lethal doses across mammalian species based on a large database
-
Rhomberg, L. R., and Wolff, S. K. 1998. Empirical scaling of single oral lethal doses across mammalian species based on a large database. Risk Anal. 18:741-753.
-
(1998)
Risk Anal
, vol.18
, pp. 741-753
-
-
Rhomberg, L.R.1
Wolff, S.K.2
-
45
-
-
0037732330
-
Evaluation of the potential impact of age- and gender-specific lung morphology and ventilation rate on the dosimetry of vapors
-
Sarangapani, R., Gentry, P.R., Covington, T.R., Teeguarden, J.G., and Clewell, H.J. 2003. Evaluation of the potential impact of age- and gender-specific lung morphology and ventilation rate on the dosimetry of vapors. Inhal. Toxicol. 15:987-1016.
-
(2003)
Inhal. Toxicol
, vol.15
, pp. 987-1016
-
-
Sarangapani, R.1
Gentry, P.R.2
Covington, T.R.3
Teeguarden, J.G.4
Clewell, H.J.5
-
46
-
-
0036686033
-
Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory-tract dosimetry in rodents and humans
-
Sarangapani, R., Teeguarden, J.G., Cruzan, G., Clewell, H., and Andersen, M.E. 2002. Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory-tract dosimetry in rodents and humans. Inhal. Toxicol. 14:789-834.
-
(2002)
Inhal. Toxicol
, vol.14
, pp. 789-834
-
-
Sarangapani, R.1
Teeguarden, J.G.2
Cruzan, G.3
Clewell, H.4
Andersen, M.E.5
-
47
-
-
0022591026
-
Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children
-
Sears, M., Jones, D. T., Holdaway, M. D., Hewitt, C. J., Flannery, E. M., Herbison, G. P., and Silva, P. A. 1986. Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children. Thorax 41:283-289.
-
(1986)
Thorax
, vol.41
, pp. 283-289
-
-
Sears, M.1
Jones, D.T.2
Holdaway, M.D.3
Hewitt, C.J.4
Flannery, E.M.5
Herbison, G.P.6
Silva, P.A.7
-
48
-
-
0028147006
-
An improved framework for uncertainty analysis: Accounting for unsuspected errors
-
Shlyakhter, A. I. 1994. An improved framework for uncertainty analysis: accounting for unsuspected errors. Risk Anal. 14:441-447.
-
(1994)
Risk Anal
, vol.14
, pp. 441-447
-
-
Shlyakhter, A.I.1
-
49
-
-
0029936262
-
Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease
-
Tashkin, D. P., Altose, M. D., Connett, J. E., Kanner, R. E., Lee, W. W., and Wise, R. A. 1996. Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 153:1802-1811.
-
(1996)
Am. J. Respir. Crit. Care Med
, vol.153
, pp. 1802-1811
-
-
Tashkin, D.P.1
Altose, M.D.2
Connett, J.E.3
Kanner, R.E.4
Lee, W.W.5
Wise, R.A.6
-
50
-
-
37549062063
-
-
U.S. 104th Congress. 1996a. Food Quality Protection Act (FQPA). P.L. 104-170. U.S. 104th Congress. http://www.epa.gov/opppsps1/fqpa/
-
U.S. 104th Congress. 1996a. Food Quality Protection Act (FQPA). P.L. 104-170. U.S. 104th Congress. http://www.epa.gov/opppsps1/fqpa/
-
-
-
-
51
-
-
37549049623
-
-
U.S. 104th Congress. 1996b. Safe Drinking Water Act (SDWA) Amendments. P.L. 104-182. U.S. 104th Congress. http://www.epa.gov/safewater/ sdwa/text.html
-
U.S. 104th Congress. 1996b. Safe Drinking Water Act (SDWA) Amendments. P.L. 104-182. U.S. 104th Congress. http://www.epa.gov/safewater/ sdwa/text.html
-
-
-
-
52
-
-
37549066567
-
-
U.S. Environmental Protection Agency. 1991. Guidelines for developmental toxicity risk assessment. Fed. Reg. 56(234):63798-63826. Washington, DC: U.S. EPA. http://www.epa.gov/ncea/raf/pdfs/devtox.pdf
-
U.S. Environmental Protection Agency. 1991. Guidelines for developmental toxicity risk assessment. Fed. Reg. 56(234):63798-63826. Washington, DC: U.S. EPA. http://www.epa.gov/ncea/raf/pdfs/devtox.pdf
-
-
-
-
53
-
-
1042264684
-
-
U.S. Environmental Protection Agency, U.S. Environmental Protection Agency, Office of the Administrator, Washington, DC
-
U.S. Environmental Protection Agency. 1995. Policy on evaluating health risks to children. U.S. Environmental Protection Agency, Office of the Administrator, Washington, DC. http://www.epa.gov/osa/spc/htm/memohlth.htm
-
(1995)
Policy on evaluating health risks to children
-
-
-
56
-
-
0005000022
-
-
U.S. Environmental Protection Agency, Office of the Administrator, Washington, DC
-
U.S. Environmental Protection Agency. 1997. Guidance on cumulative risk assessment. Part 1: Planning and scoping. Office of the Administrator, Washington, DC. http://epa.gov/osa/spc/htm/cumrisk2.htm
-
(1997)
Guidance on cumulative risk assessment. Part 1: Planning and scoping
-
-
-
57
-
-
37549054949
-
-
U.S. Environmental Protection Agency. 1998a. Guidelines for neurotoxicity risk assessment. Fed. Reg. 63(93):26926-26954. Washington, DC: U.S. EPA. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=4555
-
U.S. Environmental Protection Agency. 1998a. Guidelines for neurotoxicity risk assessment. Fed. Reg. 63(93):26926-26954. Washington, DC: U.S. EPA. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=4555
-
-
-
-
58
-
-
37549049243
-
-
U.S. Environmental Protection Agency. 1998b. Guidelines for ecological risk assessment. Fed. Reg. 63(93):26846-26924. Washington, DC: U.S. EPA. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=36512
-
U.S. Environmental Protection Agency. 1998b. Guidelines for ecological risk assessment. Fed. Reg. 63(93):26846-26924. Washington, DC: U.S. EPA. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=36512
-
-
-
-
59
-
-
37549047874
-
-
U.S. Environmental Protection Agency. 2000d. Strategy for research on environmental risks to children. U.S. Environmental Protection Agency, Office of Research and Development, Washington, D.C. EPA/600/R-00/068. http://www.epa.gov/ncea/pdfs/strat4resrch.pdf
-
U.S. Environmental Protection Agency. 2000d. Strategy for research on environmental risks to children. U.S. Environmental Protection Agency, Office of Research and Development, Washington, D.C. EPA/600/R-00/068. http://www.epa.gov/ncea/pdfs/strat4resrch.pdf
-
-
-
-
60
-
-
1842625273
-
-
U.S. Environmental Protection Agency, U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Washington, DC. EPA/600/P/00/002B
-
U.S. Environmental Protection Agency. 2002a. Child-specific exposure factor handbook (Interim report). U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Washington, DC. EPA/600/P/00/002B. http://oaspub.epa.gov/eims/ eimscomm.getfile?p_download_id=36528
-
(2002)
Child-specific exposure factor handbook (Interim report)
-
-
-
61
-
-
37549019920
-
A review of the reference dose and reference concentration processes
-
U.S. Environmental Protection Agency
-
U.S. Environmental Protection Agency. 2002b. A review of the reference dose and reference concentration processes. U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630/P-02/002F. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=36836
-
(2002)
U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630/P-02/002F
-
-
-
62
-
-
0005487191
-
-
U.S. Environmental Protection Agency, U.S. Environmental Protection Agency, Office of Pesticide Programs, Washington, DC
-
U.S. Environmental Protection Agency. 2002c. Determination of the appropriate FQPA safety factor(s) in tolerance assessment. U.S. Environmental Protection Agency, Office of Pesticide Programs, Washington, DC. http://www.epa.gov/oppfead1/trac/science/determ.pdf.
-
(2002)
Determination of the appropriate FQPA safety factor(s) in tolerance assessment
-
-
-
63
-
-
37549067606
-
Guidance on selecting the appropriate age groups for assessing childhood exposures to environmental contaminants (External review draft)
-
U.S. Environmental Protection Agency
-
U.S. Environmental Protection Agency. 2003. Guidance on selecting the appropriate age groups for assessing childhood exposures to environmental contaminants (External review draft). U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630/P-03/003A. http://oaspub.epa.gov/ eims/eimscomm.getfile?p_download_id=429113
-
(2003)
U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630/P-03/003A
-
-
-
64
-
-
37549022519
-
-
U.S. Environmental Protection Agency. 2005a. Guidelines for carcinogen risk assessment. U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630/P-R-03/001B.003. http://oaspub.epa. gov/eims/eimscomm.getfile?p_download_id=439797
-
U.S. Environmental Protection Agency. 2005a. Guidelines for carcinogen risk assessment. U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630/P-R-03/001B.003. http://oaspub.epa. gov/eims/eimscomm.getfile?p_download_id=439797
-
-
-
-
65
-
-
37549037334
-
Supplemental guidance for assessing cancer susceptibility from early-life exposure to carcinogens
-
U.S. Environmental Protection Agency
-
U.S. Environmental Protection Agency. 2005b. Supplemental guidance for assessing cancer susceptibility from early-life exposure to carcinogens. U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630600/R-03/003F. http://cfpuboaspub.epa.gov/ncea/raf/recordisplay.cfm?deid= 116283eims/eimscomm.getfile?p_download_id=36766
-
(2005)
U.S. Environmental Protection Agency, Risk Assessment Forum, Washington, DC. EPA/630600/R-03/003F
-
-
-
66
-
-
37549058281
-
-
U.S. Environmental Protection Agency. 2005c. Guidance on selecting age groups for monitoring and assessing childhood exposures to environmental contaminants. EPA/630/P-03/003F. Washington, DC: U.S. EPA. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=456258
-
U.S. Environmental Protection Agency. 2005c. Guidance on selecting age groups for monitoring and assessing childhood exposures to environmental contaminants. EPA/630/P-03/003F. Washington, DC: U.S. EPA. http://oaspub.epa.gov/eims/eimscomm.getfile?p_download_id=456258
-
-
-
-
67
-
-
37549068002
-
-
U.S. Environmental Protection Agency. 2006. Child-specific exposure factors handbook 2006 (External review draft). EPA/600/R-06/096A. Washington, DC: U.S. EPA. http://cfpub.epa.gov/ncea/cfm/recordisplay. cfm?deid=56747
-
U.S. Environmental Protection Agency. 2006. Child-specific exposure factors handbook 2006 (External review draft). EPA/600/R-06/096A. Washington, DC: U.S. EPA. http://cfpub.epa.gov/ncea/cfm/recordisplay. cfm?deid=56747
-
-
-
-
68
-
-
0034763336
-
A physiologically based pharmacokinetic model for inhalation and intravenous administration of naphthalene in rats and mice
-
Willems, B. A. T., Melnick, R. L., Kohn, M. C., and Portier, C. J. 2001. A physiologically based pharmacokinetic model for inhalation and intravenous administration of naphthalene in rats and mice. Toxicol. Appl. Pharmacol. 176:81-91.
-
(2001)
Toxicol. Appl. Pharmacol
, vol.176
, pp. 81-91
-
-
Willems, B.A.T.1
Melnick, R.L.2
Kohn, M.C.3
Portier, C.J.4
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