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Volumn , Issue , 2016, Pages 69-93

Empirically observed distributions of pharmacokinetic and pharmacodynamic variability in humans-implications for the derivation of single-point component uncertainty factors providing equivalent protection as existing reference doses

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EID: 85122908106     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (16)

References (12)
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    • (2002) Toxicology , vol.27 , pp. 115-120
    • Meek, M.E.1    Renwick, A.G.2    Chanian, E.3
  • 2
    • 0036386331 scopus 로고    scopus 로고
    • A straw man proposal for a quantitative definition of the RfD
    • Hattis D, Baird S, Goble R. A straw man proposal for a quantitative definition of the RfD. Drug Chem Toxicol 2002; 25:403-436.
    • (2002) Drug Chem Toxicol , vol.25 , pp. 403-436
    • Hattis, D.1    Baird, S.2    Goble, R.3
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    • http://www2.clarku.edu/faculty/dhattis.
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    • Human interindividual variability in parameters related to health risks
    • Hattis D, Banati P, Coble R, et al. Human interindividual variability in parameters related to health risks. Risk Anal 1999; 19:711-720.
    • (1999) Risk Anal , vol.19 , pp. 711-720
    • Hattis, D.1    Banati, P.2    Coble, R.3
  • 6
    • 0002775591 scopus 로고    scopus 로고
    • Noncancer risk assessment: A probabilistic alternative to current practice
    • Baird SJS, Cohen JT, Graham JD, et al. Noncancer risk assessment: a probabilistic alternative to current practice. Human Ecol Risk Assess 1996; 2:79-102.
    • (1996) Human Ecol Risk Assess , vol.2 , pp. 79-102
    • Baird, S.J.S.1    Cohen, J.T.2    Graham, J.D.3
  • 7
    • 0000291189 scopus 로고
    • Relationship between short and long-term feeding studies in designing an effective toxicity test
    • Weil CS, McCollister DD. Relationship between short and long-term feeding studies in designing an effective toxicity test. Agric Food Chem 1963; 11:486-491.
    • (1963) Agric Food Chem , vol.11 , pp. 486-491
    • Weil, C.S.1    McCollister, D.D.2
  • 8
    • 21444460517 scopus 로고
    • Subchronic to chronic exposure extrapolation: Toxicologic evidence for a reduced uncertainty factor
    • Nessel CS, Lewis SC, Stauber KL, et al. Subchronic to chronic exposure extrapolation: toxicologic evidence for a reduced uncertainty factor. Human Ecol Risk Assess 1995; 1:516-524.
    • (1995) Human Ecol Risk Assess , vol.1 , pp. 516-524
    • Nessel, C.S.1    Lewis, S.C.2    Stauber, K.L.3
  • 9
    • 22044431800 scopus 로고    scopus 로고
    • Accounting for missing data in noncancer risk assessment
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    • Evans JS, Baird SJS. Accounting for missing data in noncancer risk assessment. Human Ecol Risk Assess 1998; 4:291-317. [b12].
    • (1998) Human Ecol Risk Assess , vol.4 , pp. 291-317
    • Evans, J.S.1    Baird, S.J.S.2
  • 11
    • 0242501567 scopus 로고    scopus 로고
    • Differences in pharmacokinetics between children and adults. II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling
    • Hattis D, Ginsberg G, Sonawane B, et al. Differences in pharmacokinetics between children and adults. II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling. Risk Anal 2003; 23:117-142.
    • (2003) Risk Anal , vol.23 , pp. 117-142
    • Hattis, D.1    Ginsberg, G.2    Sonawane, B.3
  • 12
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    • Dose-response analysis using spreadsheets
    • Haas CN. Dose-response analysis using spreadsheets. Risk Anal 1994; 14:1097-1100.
    • (1994) Risk Anal , vol.14 , pp. 1097-1100
    • Haas, C.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.