Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5

Protein Science

Volumn 17, Issue 1, 2008, Pages 16-21

  Mosyak, Lidia ^a   Georgiadis, Katy ^a   Shane, Tania ^a   Svenson, Kristine ^a   Hebert, Tracy ^a   Mcdonagh, Thomas ^a   Mackie, Stewart ^a   Olland, Stephane ^a   Lin, Laura ^a   Zhong, Xiaotian ^a   Kriz, Ronald ^a   Reifenberg, Erica L ^a   Collins Racie, Lisa A ^a   Corcoran, Christopher ^a   Freeman, Bethany ^a   Zollner, Richard ^a   Marvell, Tod ^a   Vera, Matthew ^a   Sum, Phaik Eng ^a   Lavallie, Edward R ^a   Stahl, Mark ^a   Somers, William ^a   more..

^a PFIZER INC   (United States)

Author keywords

Aggrecanases; Enzymes; Metalloproteins; Protein structure

Indexed keywords

ADAMTS 4 PROTEIN; ADAMTS 5 PROTEIN; AGGRECANASE; METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME DEGRADATION; ENZYME STRUCTURE; FEMALE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ADAM PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; PROCOLLAGEN N-ENDOPEPTIDASE; PROTEIN CONFORMATION;

EID: 37549037806     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.073287008     Document Type: Article

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