Classification of conformational stability of protein mutants from 3D pseudo-folding graph representation of protein sequences using support vector machines

Proteins: Structure, Function and Genetics

Volumn 70, Issue 1, 2008, Pages 167-175

  Fernández, Michael ^a   Caballero, Julio ^a,b   Fernández, Leyden ^a   Abreu, Jose Ignacio ^a   Acosta, Gianco ^c  

^a UNIVERSITY OF MATANZAS   (Cuba)

^b UNIVERSIDAD DE TALCA   (Chile)

^c National Bioinformatics Center   (Cuba)

Author keywords

Graph similarity; Kernel based methods; Point mutations; Protein stability prediction

Indexed keywords

AMINO ACID; MUTANT PROTEIN; PREALBUMIN; PRION PROTEIN;

ACCURACY; AMINO ACID EUCLIDIAN DISTANCES MATRIX; AMINO ACID SEQUENCE; ARTICLE; CALCULATION; CHANGE MANAGEMENT; CLASSIFICATION; ENERGY; HUMAN; KERNEL METHOD; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; RADIAL BASIS FUNCTION KERNEL; SEQUENCE ANALYSIS; SUPPORT VECTOR MACHINE; THREE DIMENSIONAL IMAGING; THREE DIMENSIONAL PSEUDO FOLDING GRAPH; VALIDATION PROCESS;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS;

EID: 37349058879     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21524     Document Type: Article

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