Proteometric study of ghrelin receptor function variations upon mutations using amino acid sequence autocorrelation vectors and genetic algorithm-based least square support vector machines

Journal of Molecular Graphics and Modelling

Volumn 26, Issue 1, 2007, Pages 166-178

  Caballero, Julio ^a   Fernández, Leyden ^a   Garriga, Miguel ^a   Abreu, José Ignacio ^a,b   Collina, Simona ^c   Fernández, Michael ^a  

^a Faculty of Agronomy   (Cuba)

^b UNIVERSITY OF MATANZAS   (Cuba)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

7TM protein; Autocorrelation vectors; Constitutive activity; Ghrelin; Kernel based methods; Mutational studies; QSAR

Indexed keywords

GHRELIN RECEPTOR; MUTATION; PROTEOMETRIC STUDY; PUBERTY;

AMINO ACIDS; HYDROPHOBICITY; LEAST SQUARES APPROXIMATIONS; MATHEMATICAL MODELS; REGRESSION ANALYSIS; SUPPORT VECTOR MACHINES;

PROTEINS;

AMINO ACID; GHRELIN; GHRELIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; GENETIC ALGORITHM; HYDROPHOBICITY; KERNEL METHOD; MUTATION; OBESITY; PRIORITY JOURNAL; PROTEIN STRUCTURE; PUBERTY; SHORT STATURE; SUPPORT VECTOR MACHINE;

ALGORITHMS; AMINO ACID SEQUENCE; ARTIFICIAL INTELLIGENCE; DATABASES, PROTEIN; HUMANS; LEAST-SQUARES ANALYSIS; LINEAR MODELS; MODELS, MOLECULAR; MUTATION; NONLINEAR DYNAMICS; PROTEOMICS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, G-PROTEIN-COUPLED;

EID: 34250845013     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2006.11.002     Document Type: Article

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