메뉴 건너뛰기




Volumn 61, Issue SUPPL. 158, 2007, Pages 19-25

Lessons from oncology to understand and treat pulmonary hypertension

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR;

EID: 37249059051     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1742-1241.2007.01618.x     Document Type: Review
Times cited : (8)

References (32)
  • 1
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004 351 : 1425 36.
    • (2004) N Engl J Med , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 2
    • 0034776773 scopus 로고    scopus 로고
    • Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
    • Eddahibi S, Humbert M, Fadel E et al. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J Clin Invest 2001 108 : 1141 50.
    • (2001) J Clin Invest , vol.108 , pp. 1141-1150
    • Eddahibi, S.1    Humbert, M.2    Fadel, E.3
  • 3
    • 2442696430 scopus 로고    scopus 로고
    • Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension
    • Marcos E, Fadel E, Sanchez O et al. Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension. Circ Res 2004 94 : 1263 70.
    • (2004) Circ Res , vol.94 , pp. 1263-1270
    • Marcos, E.1    Fadel, E.2    Sanchez, O.3
  • 4
    • 33644865928 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: Implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
    • Teichert-Kuliszewska K, Kutryk MJ, Kuliszewski MA et al. Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ Res 2006 98 : 209 17.
    • (2006) Circ Res , vol.98 , pp. 209-217
    • Teichert-Kuliszewska, K.1    Kutryk, M.J.2    Kuliszewski, M.A.3
  • 5
    • 17944386754 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells
    • Zhang S, Fantozzi I, Tigno DD et al. Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2003 285 : L740 54.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Zhang, S.1    Fantozzi, I.2    Tigno, D.D.3
  • 6
    • 20444483234 scopus 로고    scopus 로고
    • Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
    • McMurtry MS, Archer SL, Altieri DC et al. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest 2005 115 : 1479 91.
    • (2005) J Clin Invest , vol.115 , pp. 1479-1491
    • McMurtry, M.S.1    Archer, S.L.2    Altieri, D.C.3
  • 7
    • 20444501324 scopus 로고    scopus 로고
    • Lessons learned from cancer may help in the treatment of pulmonary hypertension
    • Adnot S. Lessons learned from cancer may help in the treatment of pulmonary hypertension. J Clin Invest 2005 115 : 1461 3.
    • (2005) J Clin Invest , vol.115 , pp. 1461-1463
    • Adnot, S.1
  • 8
    • 26444540768 scopus 로고    scopus 로고
    • Reversal of experimental pulmonary hypertension by PDGF inhibition
    • Schermuly RT, Dony E, Ghofrani HA et al. Reversal of experimental pulmonary hypertension by PDGF inhibition. J Clin Invest 2005 115 : 2811 21.
    • (2005) J Clin Invest , vol.115 , pp. 2811-2821
    • Schermuly, R.T.1    Dony, E.2    Ghofrani, H.A.3
  • 9
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000 100 : 57 70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 10
    • 0027138356 scopus 로고
    • The role of p21ras in receptor tyrosine kinase signaling
    • Medema RH, Bos JL. The role of p21ras in receptor tyrosine kinase signaling. Crit Rev Oncog 1993 4 : 615 61.
    • (1993) Crit Rev Oncog , vol.4 , pp. 615-661
    • Medema, R.H.1    Bos, J.L.2
  • 12
    • 0030940521 scopus 로고    scopus 로고
    • Tenascin-C, proliferation and subendothelial accumulation of fibronectin in progressive pulmonary vascular disease
    • Jones P, Cowan K, Rabinovitch M. Tenascin-C, proliferation and subendothelial accumulation of fibronectin in progressive pulmonary vascular disease. Am J Pathol 1997 150 : 1349 60.
    • (1997) Am J Pathol , vol.150 , pp. 1349-1360
    • Jones, P.1    Cowan, K.2    Rabinovitch, M.3
  • 13
    • 0034126770 scopus 로고    scopus 로고
    • Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor
    • Cowan K, Heilbut A, Humpl T, Lam C, Ito S, Rabinovitch M. Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med 2000 6 : 698 702.
    • (2000) Nat Med , vol.6 , pp. 698-702
    • Cowan, K.1    Heilbut, A.2    Humpl, T.3    Lam, C.4    Ito, S.5    Rabinovitch, M.6
  • 14
    • 33646201514 scopus 로고    scopus 로고
    • Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: Critical role for serotonin-induced smooth muscle hyperplasia
    • Eddahibi S, Guignabert C, Barlier-Mur AM et al. Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia. Circulation 2006 113 : 1857 64.
    • (2006) Circulation , vol.113 , pp. 1857-1864
    • Eddahibi, S.1    Guignabert, C.2    Barlier-Mur, A.M.3
  • 15
    • 0029062419 scopus 로고
    • Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension
    • Humbert M, Monti G, Brenot F et al. Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension. Am J Respir Crit Care Med 1995 151 : 1628 31.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 1628-1631
    • Humbert, M.1    Monti, G.2    Brenot, F.3
  • 16
    • 0025104027 scopus 로고
    • TGF-beta stimulation and inhibition of cell proliferation: New mechanistic insights
    • Moses HL, Yang EY, Pietenpol JA. TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 1990 63 : 245 7.
    • (1990) Cell , vol.63 , pp. 245-247
    • Moses, H.L.1    Yang, E.Y.2    Pietenpol, J.A.3
  • 17
    • 33751227533 scopus 로고    scopus 로고
    • Pulmonary hypertension due to BMPR2 mutation: A new paradigm for tissue remodeling
    • Morrell NW. Pulmonary hypertension due to BMPR2 mutation: a new paradigm for tissue remodeling Proc Am Thorac Soc 2006 3 : 680 6.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 680-686
    • Morrell, N.W.1
  • 18
    • 0037046175 scopus 로고    scopus 로고
    • Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
    • Atkinson C, Stewart S, Upton PD et al. Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation 2002 105 : 1672 8.
    • (2002) Circulation , vol.105 , pp. 1672-1678
    • Atkinson, C.1    Stewart, S.2    Upton, P.D.3
  • 19
    • 33846200014 scopus 로고    scopus 로고
    • Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: Role for PDE1
    • Murray F, Patel HH, Suda RY et al. Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1. Am J Physiol Lung Cell Mol Physiol 2007 292 : L294 303.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Murray, F.1    Patel, H.H.2    Suda, R.Y.3
  • 20
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a strategy for cancer drug discovery
    • Fesik SW. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 2005 5 : 876 85.
    • (2005) Nat Rev Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 21
    • 0037267333 scopus 로고    scopus 로고
    • Validating survivin as a cancer therapeutic target
    • Altieri DC. Validating survivin as a cancer therapeutic target. Nat Rev Cancer 2003 3 : 46 54.
    • (2003) Nat Rev Cancer , vol.3 , pp. 46-54
    • Altieri, D.C.1
  • 22
    • 0037080541 scopus 로고    scopus 로고
    • Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels
    • Michelakis ED, McMurtry MS, Wu XC et al. Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels. Circulation 2002 105 : 244 50.
    • (2002) Circulation , vol.105 , pp. 244-250
    • Michelakis, E.D.1    McMurtry, M.S.2    Wu, X.C.3
  • 23
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • Taraseviciene-Stewart L, Kasahara Y, Alger L et al. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. Faseb J 2001 15 : 427 38.
    • (2001) Faseb J , vol.15 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3
  • 24
    • 33644872349 scopus 로고    scopus 로고
    • Spatio-temporal diversity of apoptosis within the vascular wall in pulmonary arterial hypertension: Heterogeneous BMP signaling may have therapeutic implications
    • Michelakis ED. Spatio-temporal diversity of apoptosis within the vascular wall in pulmonary arterial hypertension: heterogeneous BMP signaling may have therapeutic implications. Circ Res 2006 98 : 172 5.
    • (2006) Circ Res , vol.98 , pp. 172-175
    • Michelakis, E.D.1
  • 25
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005 120 : 513 22.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 26
  • 27
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1965 37 : 614 36.
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 28
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990 345 : 458 60.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 29
    • 0034003333 scopus 로고    scopus 로고
    • A critical role for telomeres in suppressing and facilitating carcinogenesis
    • Artandi SE, DePinho RA. A critical role for telomeres in suppressing and facilitating carcinogenesis. Curr Opin Genet Dev 2000 10 : 39 46.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 39-46
    • Artandi, S.E.1    Depinho, R.A.2
  • 30
    • 23244452684 scopus 로고    scopus 로고
    • Suppressing cancer: The importance of being senescent
    • Campisi J. Suppressing cancer: the importance of being senescent. Science 2005 309 : 886 7.
    • (2005) Science , vol.309 , pp. 886-887
    • Campisi, J.1
  • 31
    • 0035910729 scopus 로고    scopus 로고
    • Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension
    • Yeager ME, Halley GR, Golpon HA, Voelkel NF, Tuder RM. Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension. Circ Res 2001 88 : E2 E11.
    • (2001) Circ Res , vol.88
    • Yeager, M.E.1    Halley, G.R.2    Golpon, H.A.3    Voelkel, N.F.4    Tuder, R.M.5
  • 32
    • 0033769794 scopus 로고    scopus 로고
    • Imbalance between platelet VEGF and PDGF in pulmonary hypertension, effects of prostacyclin infusion
    • Eddahibi S, Humbert M, Sediame S et al. Imbalance between platelet VEGF and PDGF in pulmonary hypertension, effects of prostacyclin infusion. Am J Respir Crit Care Med 2000 162 : 1493 9.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1493-1499
    • Eddahibi, S.1    Humbert, M.2    Sediame, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.