-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
KERR, J.F., A.H. WYLLIE & A.R. CURRIE. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26: 239-257.
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
KERR, J.F.1
WYLLIE, A.H.2
CURRIE, A.R.3
-
2
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
THOMPSON, C.B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
THOMPSON, C.B.1
-
3
-
-
0038393112
-
Apoptosis in the development and maintenance of the immune system
-
OPFERMAN, J.T. & S.J. KORSMEYER. 2003. Apoptosis in the development and maintenance of the immune system. Nat. Immunol. 4: 410-415.
-
(2003)
Nat. Immunol
, vol.4
, pp. 410-415
-
-
OPFERMAN, J.T.1
KORSMEYER, S.J.2
-
4
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
GROSS, A., J.M. MCDONNELL & S.J. KORSMEYER. 1999. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13: 1899-1911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
GROSS, A.1
MCDONNELL, J.M.2
KORSMEYER, S.J.3
-
5
-
-
0032518787
-
-
O'CONNOR, L. et al. 1998. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 17: 384-395.
-
O'CONNOR, L. et al. 1998. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 17: 384-395.
-
-
-
-
6
-
-
0033104996
-
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
PUTHALAKATH, H. et al. 1999. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol. Cell 3: 287-296.
-
(1999)
Mol. Cell
, vol.3
, pp. 287-296
-
-
PUTHALAKATH, H.1
-
7
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
ACEHAN, D. et al. 2002. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol. Cell 9: 423-432.
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
ACEHAN, D.1
-
8
-
-
33645299092
-
Caspases at the crossroads of immune-cell life and death
-
SIEGEL, R.M. 2006. Caspases at the crossroads of immune-cell life and death. Nat. Rev. Immunol. 6: 308-317.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 308-317
-
-
SIEGEL, R.M.1
-
9
-
-
0033883377
-
The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germcells
-
O'REILLY, L.A. et al. 2000. The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germcells. Am. J. Pathol. 157: 449-461.
-
(2000)
Am. J. Pathol
, vol.157
, pp. 449-461
-
-
O'REILLY, L.A.1
-
10
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
BOUILLET, P. et al. 1999. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
BOUILLET, P.1
-
11
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
BOUILLET, P. et al. 2002. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415: 922-926.
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
BOUILLET, P.1
-
12
-
-
0035053624
-
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
-
PUTCHA, G.V. et al. 2001. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 29: 615-628.
-
(2001)
Neuron
, vol.29
, pp. 615-628
-
-
PUTCHA, G.V.1
-
13
-
-
0035049449
-
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
-
WHITFIELD, J. et al. 2001. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29: 629-643.
-
(2001)
Neuron
, vol.29
, pp. 629-643
-
-
WHITFIELD, J.1
-
14
-
-
10744232926
-
-
AKIYAMA, T. et al. 2003. Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member. Bim. Embo. J. 22: 6653-6664.
-
AKIYAMA, T. et al. 2003. Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member. Bim. Embo. J. 22: 6653-6664.
-
-
-
-
15
-
-
0033635733
-
BH3-Only proteins-essential initiators of apoptotic cell death
-
HUANG, D.C. & A. STRASSER. 2000. BH3-Only proteins-essential initiators of apoptotic cell death. Cell 103: 839-842.
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
HUANG, D.C.1
STRASSER, A.2
-
16
-
-
0035135349
-
Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors
-
SHINJYO, T. et al. 2001. Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol. Cell Biol. 21: 854-864.
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 854-864
-
-
SHINJYO, T.1
-
17
-
-
17444405985
-
Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells
-
ESSAFI, A. et al. 2005. Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells. Oncogene 24: 2317-2329.
-
(2005)
Oncogene
, vol.24
, pp. 2317-2329
-
-
ESSAFI, A.1
-
18
-
-
0042477712
-
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
-
GILLEY, J., P.J. COFFER & J. HAM. 2003. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J. Cell Biol. 162: 613-622.
-
(2003)
J. Cell Biol
, vol.162
, pp. 613-622
-
-
GILLEY, J.1
COFFER, P.J.2
HAM, J.3
-
19
-
-
23744515285
-
-
MOLLER, C. et al. 2005. Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim. Blood 106: 1330-1336.
-
MOLLER, C. et al. 2005. Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim. Blood 106: 1330-1336.
-
-
-
-
20
-
-
11144352431
-
Cytokine mediated suppression of TF-1 apoptosis requires PI3K activation and inhibition of Bim expression
-
ROSAS, M. et al. 2005. Cytokine mediated suppression of TF-1 apoptosis requires PI3K activation and inhibition of Bim expression. FEBS Lett. 579: 191-198.
-
(2005)
FEBS Lett
, vol.579
, pp. 191-198
-
-
ROSAS, M.1
-
21
-
-
0037094096
-
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
-
STAHL, M. et al. 2002. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J. Immunol. 168: 5024-5031.
-
(2002)
J. Immunol
, vol.168
, pp. 5024-5031
-
-
STAHL, M.1
-
22
-
-
10744230034
-
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
-
SUNTERS, A. et al. 2003. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J. Biol. Chem. 278: 49795-49805.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 49795-49805
-
-
SUNTERS, A.1
-
23
-
-
20444497875
-
FOXO-dependent expression of the proapoptotic protein Bim: Pivotal role for apoptosis signaling in endothelial progenitor cells
-
URBICH, C. et al. 2005. FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells. FASEB J. 19: 974-976.
-
(2005)
FASEB J
, vol.19
, pp. 974-976
-
-
URBICH, C.1
-
24
-
-
0037017396
-
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
-
DIJKERS, P.F. et al. 2002. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J. Cell Biol. 156: 531-542.
-
(2002)
J. Cell Biol
, vol.156
, pp. 531-542
-
-
DIJKERS, P.F.1
-
25
-
-
0038482050
-
-
LEY, R. et al. 2003. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein. Bim. J. Biol. Chem. 278: 18811-18816.
-
LEY, R. et al. 2003. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein. Bim. J. Biol. Chem. 278: 18811-18816.
-
-
-
-
26
-
-
23044514254
-
Regulatory phosphorylation of Bim: Sorting out the ERK from the JNK
-
LEY, R. et al. 2005. Regulatory phosphorylation of Bim: sorting out the ERK from the JNK. Cell Death Differ. 12: 1008-1014.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1008-1014
-
-
LEY, R.1
-
27
-
-
1542275411
-
Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover
-
LEY, R. et al. 2004. Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover. J. Biol. Chem. 279: 8837-8847.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 8837-8847
-
-
LEY, R.1
-
28
-
-
0242521470
-
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
-
LUCIANO, F. et al. 2003. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 22: 6785-6793.
-
(2003)
Oncogene
, vol.22
, pp. 6785-6793
-
-
LUCIANO, F.1
-
29
-
-
7444243152
-
Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity
-
HARADA, H. et al. 2004. Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity. Proc. Natl. Acad. Sci. USA 101: 15313-15317.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15313-15317
-
-
HARADA, H.1
-
30
-
-
0037147122
-
Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation
-
BISWAS, S.C. & L.A. GREENE. 2002. Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation. J. Biol. Chem. 277: 49511-49516.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 49511-49516
-
-
BISWAS, S.C.1
GREENE, L.A.2
-
31
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
LEI, K. & R.J. DAVIS. 2003. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. USA 100: 2432-2437.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2432-2437
-
-
LEI, K.1
DAVIS, R.J.2
-
32
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX dependent apoptosis
-
PUTCHA, G.V. et al. 2003. JNK-mediated BIM phosphorylation potentiates BAX dependent apoptosis. Neuron 38: 899-914.
-
(2003)
Neuron
, vol.38
, pp. 899-914
-
-
PUTCHA, G.V.1
-
33
-
-
33644865025
-
Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function
-
QI, X.J., G.M. WILDEY & P.H. HOWE. 2006. Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J. Biol. Chem. 281: 813-823.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 813-823
-
-
QI, X.J.1
WILDEY, G.M.2
HOWE, P.H.3
-
34
-
-
26444482157
-
Phosphorylation and down-regulation of Bim by muscarinic cholinergic receptor activation via protein kinase C
-
STYLES, N.A., W. ZHU & X. LI. 2005. Phosphorylation and down-regulation of Bim by muscarinic cholinergic receptor activation via protein kinase C. Neurochem. Int. 47: 519-527.
-
(2005)
Neurochem. Int
, vol.47
, pp. 519-527
-
-
STYLES, N.A.1
ZHU, W.2
LI, X.3
-
35
-
-
33646376225
-
Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons
-
MELLER, R. et al. 2006. Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. J. Biol. Chem. 281: 7429-7436.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 7429-7436
-
-
MELLER, R.1
-
36
-
-
0034707671
-
Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts
-
MIYAZAKI, T. et al. 2000. Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J. Cell Biol. 148: 333-342.
-
(2000)
J. Cell Biol
, vol.148
, pp. 333-342
-
-
MIYAZAKI, T.1
-
37
-
-
26644472432
-
An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit
-
MASUI, S. et al. 2005. An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res. 33: e43.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
MASUI, S.1
|