Dual effect of nitric oxide in immortalized and malignant human oral keratinocytes: Induction of apoptosis and differentiation

Journal of Oral Pathology and Medicine

Volumn 35, Issue 6, 2006, Pages 352-360

  Lee, S K ^a,d   Kim, H S ^a   Lee, H J ^a   Lee, J ^a   Jeon, B H ^b   Jun, C D ^c   Kim, E C ^a  

^a Wonkwang University   (South Korea)

^b Wonkwang University   (South Korea)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

^d Gangneung Wonju National University   (South Korea)

Author keywords

Apoptosis; Differentiation; Growth; Immortalized oral keratinocytes; Nitric oxide; Oral cancer

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; NITRIC OXIDE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DETERMINATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; KERATINOCYTE; MOUTH MUCOSA; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; HUMANS; KERATINOCYTES; MOUTH MUCOSA; MOUTH NEOPLASMS; NITRIC OXIDE;

EID: 33745035484     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2006.00439.x     Document Type: Article

References (40)

1. Marcus B Arenberg D Lee J, et al. Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma. Cancer 2004 15 : 2779 87.
2. Vokes EE Weichselbaum RR Lippman SM Hog WK. Head and neck cancer. N Engl J Med 1993 328 : 184 94.
3. Pignon JP Bourhis J Domenge C Designe L. Chemotheraphy added to locoregional treatment for head and neck squamous cell carcioma: three meta-analyses of updated individual data. MACH-NC collaborative group. Metaanalysis of chemotheraphy on head and neck cancer. Lancet 2000 355 : 949 55.
4. Garthwaite J Charles SL Chess-williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests a role as intracellular messenger in the brain. Nature 1988 336 : 385 8.
5. Furchgott RF Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980 288 : 373 60.
6. Busse R Mulsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett 1990 275 : 87 90.
7. Krishel V Bruch-Gerharz D Suscheck C Kroncke KD Ruzicka T Kolb-Bachofen V. Biphasic effect of exogenous nitric oxide on proliferation and differentiation in skin derived keratinocytes but not fibroblasts. J Invest Dermatol 1998 111 : 286 91.
8. Rossi A Catani MV Candi E Bernassola F Puddu P Melino G. Nitric oxide inhibits cornified envelope formation in human keratinocytes by inactivating transglutaminase and activating protein 1. J Invest Dermatol 1998 110 : 34 40.
9. Hajri A Metger E Vallat F, et al. Role of nitric oxide in pancreatic tumor growth: In vivo and in vitro studies. Br J Cancer 1998 78 : 841 9.
10. Drapier JC Wietzerbin J Hibbs JB Jr.. Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur J Immunol 1998 18 : 1587 92.
11. Kröncke KD Brener HH Rodriguez ML, et al. Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide. Biochim Biophys Acta 1993 1182 : 221 9.
12. Sandau K Brune B. The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis. Cell Signal 1996 8 : 173 7.
13. Dimmeler S Haendeler J Nehls M Zeiher AM. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1 beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32 like proteases. J Exp Med 1997 185 : 601 7.
14. Li J Bombeck CA Yang S Kim YM Billiar TR. Nitric oxide suppress apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Biol Chem 1999 274 : 17325 33.
15. Shimuzu Y Sakai M Umemura Y Ueda H. Immunohistochemical localization of nitric oxide synthase in normal human skin: expression of endothelial-type and inducible-type nitric oxide synthase in keratinocytes. J Dermatol 1997 24 : 80 7.
16. Suitani K Kamijo R Nagumo M. Cytotoxic effect of sodium nitroprusside on cancer cells: involvement of apoptosis and suppression of c-myc and c-myb proto-oncogene expression. Anticancer Res 1997 17 : 865 71.
17. Tsumori M Tanaka J Koshimura K Kawaguchi M Murakami Y Kato Y. Cytotoxic effect of nitric oxide on human hematological malignant cells. Acta Biochim Pol 2002 49 : 139 44.
18. Sokolowska M Rokita H Wlodek L. Activation of DNA biosynthesis in human hepatoblastoma HEPG2 cells by the nitric oxide donor, sodium nitroprusside. Fundam Clin Pharmacol 2003 17 : 599 607.
19. Wenzel U Kuntz S De Sousa UJ Daniel H. Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. Int J Cancer 2003 20 : 666 75.
20. Shang ZJ Li JR Li ZB. Effects of exogenous oxide on oral squamous cell carcioma: An in vitro study. J Oral Maxillofac Surg 2002 60 : 905 10.
21. Zhao SF Tong XY Zhu FD. Nitric oxide induced oral squamous cell carcinoma cells apoptosis with p53 accumulation. Oral Oncol 2005 41 : 785 90.
22. Oda D Bigler L Lee P Blanton R. HPV immortalization of human oral epithelial cells: a model for carcinogenesis. Exp Cell Res 1996 226 : 164 9.
23. Cardinali MH Pietraszkiewicz JF Robbins KC. Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies. Int J Cancer 1995 61 : 98 103.
24. Kubota T Takahara T Nagata M, et al. Colorimetric chemosensitivity testing using sulforhodamine B. J Surg Oncol 1993 52 : 83 8.
25. Thornberry NA Lazebnik Y. Caspases: enemies within. Science 1998 281 : 1312 6.
26. Yang J Liu X Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997 275 : 1129 32.
27. Ankarcrona M Dypbukt JM Brune B Nicotera P. Interleukin-1 beta induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Exp Cell Res 1994 213 : 172 7.
28. Kaneto H Fujii J Seo HG, et al. Apoptosis cell death triggered by nitric oxide in pancreatic beta cells. Diabetes 1995 44 : 733 8.
29. Fehsel K Kroncke KD Meyer KL Huber H Wahn V Kolb-Bachofen V. Nitric oxide induces apoptosis in mouse thymocytes. J Immunol 1995 155 : 2858 65.
30. Kim YM Bergonia H Lancaster JR. Nitrogen oxide-induced autoprotection in isolated rat heaptocytes. FEBS Lett 1995 374 : 228 32.
31. Suenobu N Schchiri M Iwashina M Marumo F Hirata Y. Natriuretic peptides and nitric oxide induce endothelial apoptosis via a cGMP-dependent mechanism. Arterioscler Thromb Vasc Biol 1999 19 : 140 6.
32. Battinelli E Loscalzo J. Nitric oxide induces apoptosis in megakaryocytic cell lines. Blood 2000 95 : 3451 9.
33. Taimor G Hofstaetter B Piper HM. Apoptosis induction by nitric oxide in adult cardiomyocytes via cGMP signaling and its impairment after stimulated ischemia. Cardiovasc Res 2000 45 : 588 94.
34. Kim YM De Vera ME Watkins SC Billar TR. Nitric oxide protects cultured rat hepatocytes from tumor necrosis alpha-induced apoptosis by inducing heat shock protein 70 expression. J Biol Chem 1997 272 : 1402 11.
35. Mannick JB Miao XQ Stamler JS. Nitric oxide inhibits Fas-induced apoptosis. J Biol Chem 1997 272 : 24125 8.
36. Sciorati C Rover P Ferranini M Heltai S Manfredi AA Climenti E. Autocrine nitric oxide modulates CD95-induced apoptosis in gamma delta T lymphocytes. J Biol Chem 1997 272 : 23211 5.
37. Studillo H Lopez T Castillo S Gariglio P Benitez L. p53, Bcl-2, PCNA expression, and apoptotic rates during cervical tumorigenesis. Ann N Y Acad Sci 2003 1010 : 771 4.
38. Oltvai ZN Miliman CL Korsmeyer SJ. Bcl-2 heterodimeized in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993 74 : 609 19.
39. Green DR Reed JC. Mitochondria and apoptosis. Science 1998 l28 : 1309 12.
40. Li P Nijhawan D Buduhardjo L, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptoic protease cascade. Cell 1997 91 : 479 89.