Effects of the natural isoflavonoid genistein on growth, signaling pathways and gene expression of matrix macromolecules by breast cancer cells

Mini-Reviews in Medicinal Chemistry

Volumn 6, Issue 3, 2006, Pages 331-337

  Kousidou, O Ch ^a   Tzanakakis, G N ^b   Karamanos, N K ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

Breast cancer; Estrogen receptor; Estrogens; Genistein; Signaling

Indexed keywords

COUMESTROL; DAIDZEIN; ENTERODIOL; ENTEROLACTONE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTRADIOL; ESTROGEN RECEPTOR; ESTRONE; FOCAL ADHESION KINASE; GENISTEIN; ISOFLAVONOID; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; RAS PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER INVASION; CANCER RISK; CELL PROLIFERATION; CLINICAL TRIAL; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; IN VITRO STUDY; MACROMOLECULE; NONHUMAN; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL PROLIFERATION; ESTROGEN RECEPTOR MODULATORS; FEMALE; FOCAL ADHESION KINASE 1; GENE EXPRESSION REGULATION, NEOPLASTIC; GENISTEIN; HUMANS; ISOFLAVONES; MODELS, CHEMICAL; NEOPLASM INVASIVENESS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 33646047101     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955706776073420     Document Type: Review

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