Induction of growth hormone by the roots of Astragalus membranaceus in pituitary cell culture

Archives of Pharmacal Research

Volumn 26, Issue 1, 2003, Pages 34-39

  Kim, Chungsook ^a   Ha, Hyekyung ^a   Jin, Sook Kim ^a   Yun, Tai Kim ^a   Kwon, Sun Chang ^b   Sie, Won Park ^c  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^b Biotech Research Institute   (South Korea)

^c Sangmyung University   (South Korea)

Author keywords

1 9,12 octadecadienoic acid (z,z) 2 ,3 dihydroxy propylester; 1 hexadecanoic acid 2 ,3 dihydroxy propylester; Astragalus membranaceus; Growth hormone; Leguminosae

Indexed keywords

GROWTH HORMONE; PLANT EXTRACT;

ANIMAL; ARTICLE; ASTRAGALUS MEMBRANACEUS; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; HYPOPHYSIS; ISOLATION AND PURIFICATION; MALE; METABOLISM; PLANT ROOT; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ASTRAGALUS MEMBRANACEUS; CELLS, CULTURED; GROWTH HORMONE; MALE; PITUITARY GLAND; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0041308170     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF03179928     Document Type: Article

References (26)

1. Finkenstedt, G., Gasser, R. W., Hofle, G., Watfah, C. and Fridrich, L., Effects of growth hormone (GH) replacement on bone metabolism and mineral density in adult onset of GH deficiency: results of double-blind placebo-controlled study with open follow-up. Eur. J. Endocrinol., 136, 282-289 (1997).
2. Geng, C. S., Advances in immuno-pharmacological studies on Astragalus membranaceus. Chung His I Chieh Ho Tsa Chih Chin. J. Mod. Develop. Trad. Med., 6(1), 62-4 (1986).
3. Greca, M. D., Monaco, P. and Previteva, L., Stigmasterols from Typha latifolia. J. Nat. Prod., 53, 1430-1435 (1990).
4. Harborne, J. B. and Baxter, H., Phytochemistry Dictionary. Taylor & Francis, London, pp. 673, (1993).
5. Hess, M., Meier, H. and Zeeh, B., Spektroskopische Methoden un der organischen Chemie. Georg Thieme Verlag, Stuttgart, pp. 240-241, (1991).
6. Horber, F. F. and Haymond, M. W., Human growth hormone prevents the protein catabolic side effects of prednisone in humans . J. Clin. Invest., 86, 265-272 (1990).
7. Kaiser, F. E., Silver, A. J. and Morley, J. E., The effect of recombinant human growth hormone on malnourished older individuals. J. Am. Geriat. Soc., 39, 235-240 (1991).
8. Khan, A. Q. and Malik, A., A Steroid from Calotropis procera. Phytochemistry, 28, 2859-2861 (1989).
9. Kim, C., Kim, J. S. and Park, S. J., Use of 7-Hydroxy-4′-methoxy isoflavone and its derivatives for releasing growth hormone. Korean Patent No. 0251519, (2000).
10. Kim, J. S. and Kim, C., A Study on the Constituents from the Roots of Astragalus membranaceus (II). Kor. J. Pharmacognosy, 28(2), 75-79 (1997).
11. Kim, J. S., Kim, Y. T. and Kim, C., A Study on the Constituents from the Roots of Astragalus membranaceus (I). Kor. J. Pharmacognosy, 27(4), 336-341 (1996).
12. Kobayashi, T., Sekine, K., Mackawa, Y., Suzuki, H., Shimoda, Z. and Ono, I., Additives for foods and pharmaceuticals. European Patent Apply No. EP 104043 A2, (1984).
13. Kohrt, W. M., Maily, M. T., Dalsky, G. P. and Holloszy, J. O., Body composition of healthy sedentary and trained, young and older men and women. Med. Sci. Sports Exercise, 24, 832-837 (1992).
14. Li, S. Z., Ben Cao Gang Mu (Compendium of Materia Medica). Ren Min Wei Sheng Publishing Co., Beijing, China, pp. 696, (1982).
15. Marcus, R., Butterfield, G., Holloway, L., Gilliland, L., Baylink, D. J., Hintz, R. L. and Sherman, B. W., Effects of short term administration of recombinant human growth hormone to elderly people. J. Clin. Endocrinol. Metab., 70, 519-527 (1990).
16. Pouchert, J. B. and Behnke, J., The Aldrich Library of 13C and 1H FTNMR spectra. 1, pp. 756B, (1993).
17. Pouchert, J. B. and Behnke, J., The Aldrich Library of 13C and 1H FTNMR spectra. 2, pp. 785B, (1993).
18. Ruh, M. F., Taylor, J. A., Howlett, A. C. and Welshons, W. V., Failure of cannabinoid compounds to stimulate estrogen receptors. Biochem. Pharmacol., 53(1), 35-41 (1997).
19. Siddiqui, M. T. and Siddiqui, M., Hydrolipidemic principles of Cicer arietinum: biochanin A and formononetin. Lipids., 11(3), 243-246 (1976).
20. Song, Z., Jia, Z. and Zhu, Q., Study on the components of Bupleurum sibiricum. Lanzhou Daxue Xuebao. Ziran Kexueban, 29(2), 85-89 (1993).
21. Tanaka, T., Shishiba, Y., Gout, D. W., Beer, C. T., Noble, R. L. and Friesen, H. G., Radioimmunoassay and bioassay of human growth hormone and human prolactin. J. Clin. Endocrinol., 56(1), 18-20 (1983).
22. Tang, W. and Eisenbrand, G., Chinese Drugs of Plant Origin. Springer-Verlag, Berlin, pp. 191, (1992).
23. Wang, W., Tanaka, Y., Han, Z. and Higuchi, C. M., Proliferative response of mammary glandular tissue to formononetin. Nutrit. Cancer, 23(2), 131-140 (1995).
24. Wroblewski, V. J., Masnyk, M. and Becker, G. W., Proteolytic cleavage of human growth hormone (hGH) by rat tissues in vitro: influence on the kinetics of exogenously administered hGH. Endocrinology, 129(1), 465-474 (1991).
25. Zachwieja, J. J., Bier, D. M. and Yarasheski, K. E., Growth hormone administration in older adults: effects on albumin synthesis. Am. J. Physiol., 266: (Endocrinol. Metab. 29), E840-844 (1994).
26. Zhang, Y. D., Shen, J. P., Zhu, S. H., Huang, D. K., Ding, Y. and Zhang, X. L., Effects of Astragalus on experimental liver injury. Acta. Pharmacologica. Sinica., 27(6), 401-406 (1992).