Cardiac protective effect of Astragalus on viral myocarditis mice: Comparison with Perindopril

American Journal of Chinese Medicine

Volumn 34, Issue 3, 2006, Pages 493-502

  Chen, Xiang Jian ^a   Bian, Zhi Ping ^a   Lu, Shu ^a   Xu, Jin Dan ^a   Gu, Chun Rong ^a   Yang, Di ^a   Zhang, Ji Nan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Astragalus; Endothelin; Myocarditis; Perindopril; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ASTRAGALUS MEMBRANACEUS EXTRACT; ATRIAL NATRIURETIC FACTOR; ENDOTHELIN RECEPTOR; PERINDOPRIL; TROPONIN I;

ACUTE DISEASE; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; COXSACKIE VIRUS B3; DISEASE CLASSIFICATION; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME ANALYSIS; EXPERIMENTAL DESIGN; HEART MUSCLE NECROSIS; HEART PROTECTION; INOCULATION; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PLANT ROOT; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; RECEPTOR AFFINITY; SARCOPLASMIC RETICULUM; SURVIVAL RATE; VIRUS MYOCARDITIS;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ASTRAGALUS PLANT; CARDIOTONIC AGENTS; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; PERINDOPRIL; VIRUS DISEASES;

EID: 33646709613     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X06004028     Document Type: Article

References (31)

1. Anandasabapathy, S. and W.H. Frishman. Innovative drug treatments for viral and autoimmune myocarditis. J. Clin. Pharmacol. 38: 295-308, 1998.
2. Baba, T., T. Kanda and I. Kobayashi. Reduction of cardiac endothelin-1 by angiotensin II type 1 receptor antagonist in viral myocarditis of mice. Life Sci. 67: 587-597, 2000.
3. Beck, M.A., N.M. Chapman, B.M. McManus, J.C. Mullican and S. Tracy. Secondary enterovirus infection in the murine model of myocarditis. Pathologic and immunologic aspects. Am. J. Pathol. 136: 669-681, 1990.
4. Beck, M.A. Increased virulence of coxsackievirus B3 in mice due to vitamin E or selenium deficiency. J. Nutr. 127: 966S-970S, 1997.
5. Chen, P. and J. Zhou. Abnormal metabolism of nitric oxide, oxidative stress and lipoperoxidative stress in patients with acute viral myocarditis. Chin. Med. J. (Engl.) 114: 1132-1135, 2001.
6. Duchman, S.M., V. Thohan, D. Kalra and G. Torre-Amione. Endothelin-1: A new target of therapeutic intervention for the treatment of heart failure. Curr. Opin. Cardiol. 15: 136-140, 2000.
7. Hu, X., H. Wang, W. Lu, Y. Dong and P. Cheng. The study on intramyocardial calcium overload and apoptosis induced by coxsackievirus B3. J. Tongji. Med. Univ. 21: 256=258, 262, 2001.
8. Kanda, T., M. Araki, M. Nakano, S. Imai, T. Suzuki, K. Murata and I. Kobayashi. Chronic effect of Losartan in a murine model of dilated cardiomyopathy: Comparison with Captopril. J. Pharmacol. Exp. Ther. 273: 955-958, 1995.
9. Kearney, M.T., J.M. Cotton, P.J. Richardson and A.M. Shah. Viral myocarditis and dilated cardiomyopathy: Mechanisms, manifestations, and management. Postgrad. Med. J. 77: 4-10, 2001.
10. Kishimoto, C., K. Shioji, M. Kinoshita, T. Iwase, S. Tamaki, M. Fujii, A. Murashige, H. Maruhashi, S. Takeda, H. Nonogi and T. Hashimoto. Treatment of acute inflammatory cardiomyopathy with intravenous immunoglobulin ameliorates left ventricular function associated with suppression of inflammatory cytokines and decreased oxidative stress. Int. J. Cardiol. 91: 173-178, 2003.
11. 2+-dependent pNPPase. Age-dependent changes. Basic Res. Cardiol. 90: 323-331, 1995.
12. Lu, S. and J.N. Zhang. Study development of the cardiovascular pharmacological effects of Astragalus. Zhong Cao Yao 29: 59-61, 1998.
13. Ma, X.Q., Q. Shi, J.A. Duan, T.T. Dong and K.W. Tsim. Chemical analysis of Radix Astragali (Huangqi) in China: A comparison with its adulterants and seasonal variations. J. Agric. Food Chem. 50: 4861-4866, 2002.
14. Meng, D., X.J. Chen, Y.Y. Bian, P. Li, D. Yang and J.N. Zhang. Effect of astragalosides on intracellular calcium overload in cultured cardiac myocytes of neonatal rats. Am. J. Chin. Med. 33: 11-20, 2005.
15. Modesti, P.A., S. Vanni, R. Paniccia, B. Bandinelli, I. Bertolozzi, G. Polidori, G. Sani and G.G.N. Serneri. Characterization of endothelin-1 receptor subtypes in isolated human cardiomyocytes. J. Cardiovasc. Pharmacol. 34: 333-339, 1999.
16. Nakamura, H., T. Yamamoto, T. Yamamura, F. Nakao, S. Umemoto, T. Shintaku, K. Yamaguchi, P. Liu and M. Matsuzaki. Repetitive coxsackievirus infection induces cardiac dilatation in post-myocarditic mice. Jpn. Circ. J. 63: 794-802, 1999.
17. 3 and encephalomyocarditis virus: An animal model of chronic myocarditis. J. Pathol. 167: 341-347, 1992.
18. Ono, K., A. Matsumori, T. Shioi, Y. Furukawa and S. Sasayama. Contribution of endothelin-1 to myocardial injury in a murine model of myocarditis: Acute effects of bosentan, an endothelin receptor antagonist. Circulation 100: 1823-1829, 1999.
19. Peng, T., Y. Yang, H. Riesemann and R. Kandolf. The inhibitory effect of astragalus membranaceus on coxsackie B-3 virus RNA replication. Chin. Med. Sci. J. 10: 146-150, 1995.
20. Petkova, S.B., H.B. Tanowitz, H.I. Magazine, S.M. Factor, J. Chan, R.G. Pestell, B. Bouzahzah, S.A. Douglas, V. Shtutin, S.A. Morris, E. Tsang, L.M. Weiss, G.J. Christ, M. Winner and H. Huang. Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection. Cardiovasc Pathol. 9: 257-265, 2000.
21. 2+ uptake. Circulation 102: 1582-1588, 2000.
22. Seta, Y., T. Kanda, T. Yokoyama, M. Arai, K. Sekiguchi, T. Tanaka, I. Kobayashi, M. Kurabayashi and R. Nagai. Therapy with the nonpeptide endothelin receptor antagonist 97-139 in a murine model of congestive heart failure. Jpn. Heart J. 41: 79-85, 2000.
23. Sharaf, A.R., J. Narula, P.D. Nicol, J.F. Southern and B.A. Khaw. Cardiac sarcoplasmic reticulum calcium ATPase, an autoimmune antigen in experimental cardiomyopathy. Circulation 89: 1217-1228, 1994.
24. Takata, S., H. Nakamura, S. Umemoto, K. Yamaguchil, T. Sekine, T. Kato, K. Nishioka and M. Matsuzaki. Identification of autoantibodies with the corresponding antigen for repetitive coxsackievirus infection-induced cardiomyopathy. Circ. J. 68: 677-682, 2004.
25. Wu, L., H. Liu, P. Xue, Z.G. Lu and K.F. Du. Influence of a triplex superimposed treatment on HBV replication and mutation during treating chronic hepatitis B. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 15: 236-238, 2001.
26. Yang, Y.Z. Treatement: Astragalus. In: Y.Z. Yang Viral Heart Diseases, Shanghai Scientific & Techincal Publishers, Shaihai, 2001, pp. 110-127.
27. Yin, X., Y. Zhang, H. Wu, X. Zhu, X. Zheng, S. Jiang, H. Zhuo, J. Shen, L. Li and J. Qiu. Protective effects of Astragalus saponin I on early stage of diabetic nephropathy in rats. J. Pharmacol. Sci. 95: 256-266, 2004.
28. Zhang, J.N., E.B. Su, J. Wei, M.H. Zhao, Z.Q. Liu, Y.Z Rong and W.Z. Ma. Elevation of cardiac troponin I and its association with diagnosis and progress of viral myocarditis. Zhonghua Xin Xue Guan Bing Za Zhi 27: 421-424, 1999.
29. Zheng, Z., D. Liu, C. Song, C. Cheng and Z. Hu. Studies on chemical constituents and immunological function activity of hairy root of Astragalus membranaceus. Chin. J. Biotechnol. 14: 93-97, 1998.
30. Zolk, O.J., J. Quattek, G. Sitzler, T. Schrader, G. Nickenig, P. Schnabel, K. Shimada, M. Takahashi and M. Bohm. Expression of endothelin-1, endothelin-converting enzyme, and endothelin receptors in chronic heart failure. Circulation 99: 2118-2123, 1999.
31. Zou, Y.H. and X.M. Liu. Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer. Zhongguo Zhong Xi Yi Jie He Za Zhi 23: 733-735, 2003.