Role of purinoceptors in immune-mediated disease (therapies targeting the P2X7 receptor)

Drug Discovery Today: Therapeutic Strategies

Volumn 4, Issue 1, 2007, Pages 33-37

  Tsukimoto, Mitsutoshi ^a   Harada, Hitoshi ^b   Degawa, Masakuni ^b  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

A 740003; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AZ 11645373; CYTOKINE; INTERLEUKIN 1BETA; ION CHANNEL; L SELECTIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; OXIDIZED ADENOSINE TRIPHOSPHATE; PHOSPHATIDYLSERINE; PURINE P2X7 RECEPTOR BLOCKING AGENT; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; STYLISSADINE A; STYLISSADINE B; UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; AMINO ACID SUBSTITUTION; ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; CATALYSIS; CELL DEATH; CELL MEMBRANE PERMEABILITY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG ISOLATION; DRUG SELECTIVITY; DRUG TARGETING; GENETIC POLYMORPHISM; HUMAN; HYPERALGESIA; IMMUNE SYSTEM; IMMUNOPATHOGENESIS; IMMUNOPATHOLOGY; IMMUNOREGULATION; INFLAMMATION; LYMPHOCYTE MIGRATION; MACROPHAGE ACTIVATION; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; RECEPTOR BINDING; RECEPTOR UPREGULATION; REVIEW; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE;

EID: 37249025702     PISSN: 17406773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddstr.2007.06.002     Document Type: Review

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