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Volumn 236, Issue 12, 2007, Pages 3208-3217

Transdifferentiation in developmental biology, disease, and in therapy

Author keywords

Cell therapy; Metaplasia; Regeneration; Transdifferentiation

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; INSULIN;

EID: 37249012804     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21336     Document Type: Review
Times cited : (42)

References (105)
  • 1
    • 0023484414 scopus 로고
    • Cell cycles and in vitro transdifferentiation and regeneration of isolated, striated muscle of jellyfish
    • Alder H, Schmid V. 1987. Cell cycles and in vitro transdifferentiation and regeneration of isolated, striated muscle of jellyfish. Dev Biol 124:358-369.
    • (1987) Dev Biol , vol.124 , pp. 358-369
    • Alder, H.1    Schmid, V.2
  • 2
    • 17544363798 scopus 로고    scopus 로고
    • Transdifferentiation of larval flagellated cells to choanocytes in the metamorphosis of the Demosponge Haliclona permollis
    • Amano S, Hori I. 1996. Transdifferentiation of larval flagellated cells to choanocytes in the metamorphosis of the Demosponge Haliclona permollis. Biol Bull 190: 161-172.
    • (1996) Biol Bull , vol.190 , pp. 161-172
    • Amano, S.1    Hori, I.2
  • 3
    • 72849170034 scopus 로고
    • Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer
    • Auerbach O, Stout AP, Hammond EC, Garfinkel L. 1961. Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer. N Engl J Med 265:253-267.
    • (1961) N Engl J Med , vol.265 , pp. 253-267
    • Auerbach, O.1    Stout, A.P.2    Hammond, E.C.3    Garfinkel, L.4
  • 4
    • 0027397539 scopus 로고
    • Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1 (TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts
    • Bachern MG, Sell KM, Melchior R, Kropf J, Eller T, Gressner AM. 1993. Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1 (TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts. Virchows Arch B Cell Pathol Incl Mol Pathol 63:123-130.
    • (1993) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.63 , pp. 123-130
    • Bachern, M.G.1    Sell, K.M.2    Melchior, R.3    Kropf, J.4    Eller, T.5    Gressner, A.M.6
  • 5
    • 12944327377 scopus 로고    scopus 로고
    • In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
    • Baeyens L, De Breuck S, Lardon J, Mfopou JK, Rooman I, Bouwens L. 2005. In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells. Diabetologia 48:49-57.
    • (2005) Diabetologia , vol.48 , pp. 49-57
    • Baeyens, L.1    De Breuck, S.2    Lardon, J.3    Mfopou, J.K.4    Rooman, I.5    Bouwens, L.6
  • 6
    • 0000051338 scopus 로고
    • The lower esophagus lined by columnar epithelium
    • Barrett NR. 1957. The lower esophagus lined by columnar epithelium. Surgery 41:881-894.
    • (1957) Surgery , vol.41 , pp. 881-894
    • Barrett, N.R.1
  • 7
    • 0028260056 scopus 로고
    • Pancreas transplantation in diabetic humans normalizes hepatic glucose production during hypoglycemia
    • Barrou Z, Seaquist ER, Robertson RP. 1994. Pancreas transplantation in diabetic humans normalizes hepatic glucose production during hypoglycemia. Diabetes 43:661-666.
    • (1994) Diabetes , vol.43 , pp. 661-666
    • Barrou, Z.1    Seaquist, E.R.2    Robertson, R.P.3
  • 8
    • 0032832511 scopus 로고    scopus 로고
    • Gut specific expression using mammalian promoters in transgenic Xenopus laevis
    • Beck CW, Slack JM. 1999. Gut specific expression using mammalian promoters in transgenic Xenopus laevis. Mech Dev 88: 221-227.
    • (1999) Mech Dev , vol.88 , pp. 221-227
    • Beck, C.W.1    Slack, J.M.2
  • 10
    • 85047690508 scopus 로고    scopus 로고
    • Opinion: The origin of the cancer stem cell: current controversies and new insights
    • Bjerkvig R, Tysnes BB, Aboody KS, Najbauer J, Terzis AJ. 2005. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer 5:899-904.
    • (2005) Nat Rev Cancer , vol.5 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.5
  • 11
    • 0001818103 scopus 로고
    • Zoogeography and life cycle patterns of Mediterranean hydromedusae
    • Boero F, Bouillon J. 1993. Zoogeography and life cycle patterns of Mediterranean hydromedusae. Biol J Linn Soc 48:239-266.
    • (1993) Biol J Linn Soc , vol.48 , pp. 239-266
    • Boero, F.1    Bouillon, J.2
  • 12
    • 0001893680 scopus 로고
    • Ultrastructure de la larve parenchymella d'Hamigera hamigera (Schmidt) (Demosponge, Poecilosclerida). Origines des cellules grises
    • Mar 17
    • Boury-Esnault N. 1976. Ultrastructure de la larve parenchymella d'Hamigera hamigera (Schmidt) (Demosponge, Poecilosclerida). Origines des cellules grises. Cah Biol Mar 17:9-20.
    • (1976) Cah Biol , pp. 9-20
    • Boury-Esnault, N.1
  • 14
    • 0036346608 scopus 로고    scopus 로고
    • Plasticity and reprogramming of differentiated cells in amphibian regeneration
    • Brockes JP, Kumar A. 2002. Plasticity and reprogramming of differentiated cells in amphibian regeneration. Nat Rev Mol Cell Biol 3:566-574.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 566-574
    • Brockes, J.P.1    Kumar, A.2
  • 15
    • 28444440251 scopus 로고    scopus 로고
    • Characterization of liver function in transdifferentiated hepatocytes
    • Burke ZD, Shen CN, Ralphs KL, Tosh D. 2006. Characterization of liver function in transdifferentiated hepatocytes. J Cell Physiol 206:147-159.
    • (2006) J Cell Physiol , vol.206 , pp. 147-159
    • Burke, Z.D.1    Shen, C.N.2    Ralphs, K.L.3    Tosh, D.4
  • 16
    • 34249799591 scopus 로고    scopus 로고
    • Stem cells in the adult pancreas and liver
    • Burke ZD, Thowfeequ S, Peran M, Tosh D. 2007. Stem cells in the adult pancreas and liver. Biochem J 404:169-178.
    • (2007) Biochem J , vol.404 , pp. 169-178
    • Burke, Z.D.1    Thowfeequ, S.2    Peran, M.3    Tosh, D.4
  • 18
    • 0016967667 scopus 로고
    • Stromal induction and specification of morphogenesis and cytodifferentiation of the epithelia of the Mullerian ducts and urogenital sinus during development of the uterus and vagina in mice
    • Cunha GR. 1976. Stromal induction and specification of morphogenesis and cytodifferentiation of the epithelia of the Mullerian ducts and urogenital sinus during development of the uterus and vagina in mice. J Exp Zool 196:361-370.
    • (1976) J Exp Zool , vol.196 , pp. 361-370
    • Cunha, G.R.1
  • 19
    • 33846608406 scopus 로고
    • A study of growth and cell differentiation in the hepato-pancreas of the crayfish
    • David LE, Burnett AL. 1964. A study of growth and cell differentiation in the hepato-pancreas of the crayfish. Dev Biol 10:122-153.
    • (1964) Dev Biol , vol.10 , pp. 122-153
    • David, L.E.1    Burnett, A.L.2
  • 20
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis RL, Weintraub H, Lassar AB. 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51: 987-1000.
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 21
    • 24144498763 scopus 로고    scopus 로고
    • CDX2 is a useful marker of intestinal-type differentiation: A tissue microarray-based study of 629 tumors from various sites
    • De Lott LB, Morrison C, Suster S, Cohn DE, Frankel WL. 2005. CDX2 is a useful marker of intestinal-type differentiation: a tissue microarray-based study of 629 tumors from various sites. Arch Pathol Lab Med 129:1100-1105.
    • (2005) Arch Pathol Lab Med , vol.129 , pp. 1100-1105
    • De Lott, L.B.1    Morrison, C.2    Suster, S.3    Cohn, D.E.4    Frankel, W.L.5
  • 22
    • 0035072545 scopus 로고    scopus 로고
    • A bipotential precursor population for pancreas and liver within the embryonic endoderm
    • Deutsch G, Jung J, Zheng M, Lora J, Zaret KS. 2001. A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development 128: 871-881.
    • (2001) Development , vol.128 , pp. 871-881
    • Deutsch, G.1    Jung, J.2    Zheng, M.3    Lora, J.4    Zaret, K.S.5
  • 23
    • 0000679767 scopus 로고
    • Genomic potential of differentiated cells analyzed by nuclear transplantation
    • Diberardino MA. 1987. Genomic potential of differentiated cells analyzed by nuclear transplantation. Am Zool 27:623-644.
    • (1987) Am Zool , vol.27 , pp. 623-644
    • Diberardino, M.A.1
  • 24
    • 0001058943 scopus 로고    scopus 로고
    • Regeneration in echinoderms
    • Dolmatov IY. 1999. Regeneration in echinoderms. Russ J Mar Biol 25:225-233.
    • (1999) Russ J Mar Biol , vol.25 , pp. 225-233
    • Dolmatov, I.Y.1
  • 25
    • 0025649363 scopus 로고
    • The corneoscleral limbus in human corneal epithelial wound healing
    • Dua HS, Forrester JV. 1990. The corneoscleral limbus in human corneal epithelial wound healing. Am J Ophthalmol 110:646-656.
    • (1990) Am J Ophthalmol , vol.110 , pp. 646-656
    • Dua, H.S.1    Forrester, J.V.2
  • 29
    • 14344253639 scopus 로고    scopus 로고
    • Barrett's oesophagus and oesophageal adenocarcinoma: How does acid interfere with cell proliferation and differentiation?
    • Fitzgerald RC. 2005. Barrett's oesophagus and oesophageal adenocarcinoma: how does acid interfere with cell proliferation and differentiation? Gut 54(Suppl 1):i21-i26.
    • (2005) Gut , vol.54 , Issue.SUPPL. 1
    • Fitzgerald, R.C.1
  • 30
    • 0033939028 scopus 로고    scopus 로고
    • Increased lung expansion alters the proportions of type I and type II alveolar epithelial cells in fetal sheep
    • Flecknoe S, Harding R, Maritz G, Hooper SB. 2000. Increased lung expansion alters the proportions of type I and type II alveolar epithelial cells in fetal sheep. Am J Physiol Lung Cell Mol Physiol 278: L1180-L1185.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278
    • Flecknoe, S.1    Harding, R.2    Maritz, G.3    Hooper, S.B.4
  • 32
    • 34248207324 scopus 로고    scopus 로고
    • Biomarkers of liver fibrosis: Clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests
    • Gressner OA, Weiskirchen R, Gressner AM. 2007. Biomarkers of liver fibrosis: clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests. Clin Chim Acta 381:107-113.
    • (2007) Clin Chim Acta , vol.381 , pp. 107-113
    • Gressner, O.A.1    Weiskirchen, R.2    Gressner, A.M.3
  • 33
  • 34
    • 0017118556 scopus 로고    scopus 로고
    • Hakim RS. 1976. Structural changes occurring during transformation of the labial gland cells to their adult form, in Manduca sexta. J Morphol 149:547-566.
    • Hakim RS. 1976. Structural changes occurring during transformation of the labial gland cells to their adult form, in Manduca sexta. J Morphol 149:547-566.
  • 36
    • 0029157019 scopus 로고
    • Transformations between epithelium and mesenchyme: Normal, pathological, and experimentally induced
    • Hay ED, Zuk A. 1995. Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced. Am J Kidney Dis 26:678-690.
    • (1995) Am J Kidney Dis , vol.26 , pp. 678-690
    • Hay, E.D.1    Zuk, A.2
  • 37
    • 1042265557 scopus 로고    scopus 로고
    • Ultrastructure of goblet-cell metaplasia from Clara cell in the allergic asthmatic airway inflammation in a mouse model of asthma in vivo
    • Hayashi T, Ishii A, Nakai S, Hasegawa K. 2004. Ultrastructure of goblet-cell metaplasia from Clara cell in the allergic asthmatic airway inflammation in a mouse model of asthma in vivo. Virchows Arch 444:66-73.
    • (2004) Virchows Arch , vol.444 , pp. 66-73
    • Hayashi, T.1    Ishii, A.2    Nakai, S.3    Hasegawa, K.4
  • 38
    • 0037458120 scopus 로고    scopus 로고
    • Experimental conversion of liver to pancreas
    • Horb ME, Shen CN, Tosh D, Slack JM. 2003. Experimental conversion of liver to pancreas. Curr Biol 13:105-115.
    • (2003) Curr Biol , vol.13 , pp. 105-115
    • Horb, M.E.1    Shen, C.N.2    Tosh, D.3    Slack, J.M.4
  • 39
    • 0035084164 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells
    • Hui H, Wright C, Perfetti R. 2001. Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells. Diabetes 50:785-796.
    • (2001) Diabetes , vol.50 , pp. 785-796
    • Hui, H.1    Wright, C.2    Perfetti, R.3
  • 44
    • 15944417831 scopus 로고    scopus 로고
    • PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
    • Kaneto H, Nakatani Y, Miyatsuka T, Matsuoka TA, Matsuhisa M, Hori M, Yamasaki Y. 2005b. PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 54:1009-1022.
    • (2005) Diabetes , vol.54 , pp. 1009-1022
    • Kaneto, H.1    Nakatani, Y.2    Miyatsuka, T.3    Matsuoka, T.A.4    Matsuhisa, M.5    Hori, M.6    Yamasaki, Y.7
  • 45
    • 0003100192 scopus 로고
    • Sexual reproduction in four Caribbean commercial sponges. III. Larval behaviour, settlement and metamorphosis
    • Kaye HR, Reiswig HM. 1991. Sexual reproduction in four Caribbean commercial sponges. III. Larval behaviour, settlement and metamorphosis. Invertebr Reprod Dev 19:25-35.
    • (1991) Invertebr Reprod Dev , vol.19 , pp. 25-35
    • Kaye, H.R.1    Reiswig, H.M.2
  • 46
    • 0032555944 scopus 로고    scopus 로고
    • The muscle regulatory factors MyoD and myf-5 undergo distinct cell cycle-specific expression in muscle cells
    • Kitzmann M, Carnac G, Vandromme M, Primig M, Lamb NJ, Fernandez A. 1998. The muscle regulatory factors MyoD and myf-5 undergo distinct cell cycle-specific expression in muscle cells. J Cell Biol 142:1447-1459.
    • (1998) J Cell Biol , vol.142 , pp. 1447-1459
    • Kitzmann, M.1    Carnac, G.2    Vandromme, M.3    Primig, M.4    Lamb, N.J.5    Fernandez, A.6
  • 47
    • 0038413922 scopus 로고    scopus 로고
    • NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice
    • Kojima H, Fujimiya M, Matsumura K, Younan P, Imaeda H, Maeda M, Chan L. 2003. NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat Med 9: 596-603.
    • (2003) Nat Med , vol.9 , pp. 596-603
    • Kojima, H.1    Fujimiya, M.2    Matsumura, K.3    Younan, P.4    Imaeda, H.5    Maeda, M.6    Chan, L.7
  • 48
    • 0033065925 scopus 로고    scopus 로고
    • Pancreatic expression of keratinocyte growth factor leads to differentiation of islet hepatocytes and proliferation of duct cells
    • Krakowski ML, Kritzik MR, Jones EM, Krahl T, Lee J, Arnush M, Gu D, Sarvetnick N. 1999. Pancreatic expression of keratinocyte growth factor leads to differentiation of islet hepatocytes and proliferation of duct cells. Am J Pathol 154: 683-691.
    • (1999) Am J Pathol , vol.154 , pp. 683-691
    • Krakowski, M.L.1    Kritzik, M.R.2    Jones, E.M.3    Krahl, T.4    Lee, J.5    Arnush, M.6    Gu, D.7    Sarvetnick, N.8
  • 50
  • 51
    • 20544473735 scopus 로고    scopus 로고
    • The initiation of liver development is dependent on Foxa transcription factors
    • Lee CS, Friedman JR, Fulmer JT, Kaestner KH. 2005. The initiation of liver development is dependent on Foxa transcription factors. Nature 435:944-947.
    • (2005) Nature , vol.435 , pp. 944-947
    • Lee, C.S.1    Friedman, J.R.2    Fulmer, J.T.3    Kaestner, K.H.4
  • 52
    • 20444406125 scopus 로고    scopus 로고
    • In vitro transdifferentiation of hepatoma cells into functional pancreatic cells
    • Li WC, Horb ME, Tosh D, Slack JM. 2005a. In vitro transdifferentiation of hepatoma cells into functional pancreatic cells. Mech Dev 122:835-847.
    • (2005) Mech Dev , vol.122 , pp. 835-847
    • Li, W.C.1    Horb, M.E.2    Tosh, D.3    Slack, J.M.4
  • 54
    • 30344440788 scopus 로고    scopus 로고
    • Transdifferentiation in holothurian gut regeneration
    • Mashanov VS, Dolmatov IY, Heinzeller T. 2005. Transdifferentiation in holothurian gut regeneration. Biol Bull 209:184-193.
    • (2005) Biol Bull , vol.209 , pp. 184-193
    • Mashanov, V.S.1    Dolmatov, I.Y.2    Heinzeller, T.3
  • 57
    • 0036402142 scopus 로고    scopus 로고
    • The diet, prostate inflammation, and the development of prostate cancer
    • Nelson WG, DeWeese TL, DeMarzo AM. 2002. The diet, prostate inflammation, and the development of prostate cancer. Cancer Metastasis Rev 21:3-16.
    • (2002) Cancer Metastasis Rev , vol.21 , pp. 3-16
    • Nelson, W.G.1    DeWeese, T.L.2    DeMarzo, A.M.3
  • 59
    • 0022613184 scopus 로고
    • Transdifferentiation in animal cells: Fact or artifact?
    • Okada TS. 1986. Transdifferentiation in animal cells: fact or artifact? Dev Growth Differ 28:213-221.
    • (1986) Dev Growth Differ , vol.28 , pp. 213-221
    • Okada, T.S.1
  • 61
    • 0031951493 scopus 로고    scopus 로고
    • Direct transdifferentiation in the vertebrate retina
    • Opas M, Dziak E. 1998. Direct transdifferentiation in the vertebrate retina. Int J Dev Biol 42:199-206.
    • (1998) Int J Dev Biol , vol.42 , pp. 199-206
    • Opas, M.1    Dziak, E.2
  • 62
    • 0034913198 scopus 로고    scopus 로고
    • Formation of retinal pigment epithelium in vitro by transdifferentiation of neural retina cells
    • Opas M, Davies JR, Zhou Y, Dziak E. 2001. Formation of retinal pigment epithelium in vitro by transdifferentiation of neural retina cells. Int J Dev Biol 45:633-642.
    • (2001) Int J Dev Biol , vol.45 , pp. 633-642
    • Opas, M.1    Davies, J.R.2    Zhou, Y.3    Dziak, E.4
  • 63
    • 0029776722 scopus 로고    scopus 로고
    • Reversing the life cycle: Medusae transforming into polyps and cell transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa)
    • Piraino S, Boero F, Aeschbach B, Schmid V. 1996. Reversing the life cycle: Medusae transforming into polyps and cell transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa). Biol Bull 190:302-312.
    • (1996) Biol Bull , vol.190 , pp. 302-312
    • Piraino, S.1    Boero, F.2    Aeschbach, B.3    Schmid, V.4
  • 65
    • 0022617147 scopus 로고
    • Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion
    • Rao MS, Subbarao V, Reddy JK. 1986. Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion. Cell Differ 18:109-117.
    • (1986) Cell Differ , vol.18 , pp. 109-117
    • Rao, M.S.1    Subbarao, V.2    Reddy, J.K.3
  • 66
    • 33746413027 scopus 로고    scopus 로고
    • Epithelial stem cells of the lung: Privileged few or opportunities for many?
    • Rawlins EL, Hogan BL. 2006. Epithelial stem cells of the lung: privileged few or opportunities for many? Development 133:2455-2465.
    • (2006) Development , vol.133 , pp. 2455-2465
    • Rawlins, E.L.1    Hogan, B.L.2
  • 67
    • 0025728572 scopus 로고
    • Pancreatic hepatocytes. An in vivo model for cell lineage in pancreas of adult rat
    • Reddy JK, Rao MS, Yeldandi AV, Tan XD, Dwivedi RS. 1991. Pancreatic hepatocytes. An in vivo model for cell lineage in pancreas of adult rat. Dig Dis Sci 36:502-509.
    • (1991) Dig Dis Sci , vol.36 , pp. 502-509
    • Reddy, J.K.1    Rao, M.S.2    Yeldandi, A.V.3    Tan, X.D.4    Dwivedi, R.S.5
  • 68
    • 26044457942 scopus 로고    scopus 로고
    • Current practices of donor pancreas allocation in the UK: Future implications for pancreas and islet transplantation
    • Ridgway DM, White SA, Kimber RM, Nicholson ML. 2005. Current practices of donor pancreas allocation in the UK: future implications for pancreas and islet transplantation. Transpl Int 18:828-834.
    • (2005) Transpl Int , vol.18 , pp. 828-834
    • Ridgway, D.M.1    White, S.A.2    Kimber, R.M.3    Nicholson, M.L.4
  • 69
    • 0033610491 scopus 로고    scopus 로고
    • A pilot study of immunosuppressive monotherapy in liver transplantation: Tacrolimus versus microemulsified cyclosporin
    • Rolles K, Davidson BR, Burroughs AK. 1999. A pilot study of immunosuppressive monotherapy in liver transplantation: tacrolimus versus microemulsified cyclosporin. Transplantation 68:1195-1198.
    • (1999) Transplantation , vol.68 , pp. 1195-1198
    • Rolles, K.1    Davidson, B.R.2    Burroughs, A.K.3
  • 71
    • 33645883815 scopus 로고    scopus 로고
    • Gene therapy for diabetes: Reinventing the islet
    • Samson SL, Chan L. 2006. Gene therapy for diabetes: reinventing the islet. Trends Endocrinol Metab 17:92-100.
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 92-100
    • Samson, S.L.1    Chan, L.2
  • 72
    • 0035723885 scopus 로고    scopus 로고
    • Limbal stem cells in health and disease
    • Sangwan VS. 2001. Limbal stem cells in health and disease. Biosci Rep 21:385-405.
    • (2001) Biosci Rep , vol.21 , pp. 385-405
    • Sangwan, V.S.1
  • 74
    • 0029320613 scopus 로고
    • Transdifferentiation of isolated striated muscle of jellyfish in vitro: The initiation process
    • Schmid V, Reber-Muller S. 1995. Transdifferentiation of isolated striated muscle of jellyfish in vitro: the initiation process. Semin Cell Biol 6:109-116.
    • (1995) Semin Cell Biol , vol.6 , pp. 109-116
    • Schmid, V.1    Reber-Muller, S.2
  • 75
    • 0024230546 scopus 로고
    • Transdifferentiation from striated muscle of medusae in vitro
    • Schmid V, Alder H, Plickert G, Weber C. 1988. Transdifferentiation from striated muscle of medusae in vitro. Cell Differ Dev 25(Suppl):137-146.
    • (1988) Cell Differ Dev , vol.25 , Issue.SUPPL. , pp. 137-146
    • Schmid, V.1    Alder, H.2    Plickert, G.3    Weber, C.4
  • 77
    • 0035752662 scopus 로고    scopus 로고
    • Diabetes. Islet cell transplantation
    • Shapiro AM, Ryan EA, Lakey JR. 2001. Diabetes. Islet cell transplantation. Lancet 358(Suppl):S21.
    • (2001) Lancet , vol.358 , Issue.SUPPL.
    • Shapiro, A.M.1    Ryan, E.A.2    Lakey, J.R.3
  • 78
    • 14244257340 scopus 로고    scopus 로고
    • Adipogenic transcriptional regulation of hepatic stellate cells
    • She H, Xiong S, Hazra S, Tsukamoto H. 2005. Adipogenic transcriptional regulation of hepatic stellate cells. J Biol Chem 280:4959-4967.
    • (2005) J Biol Chem , vol.280 , pp. 4959-4967
    • She, H.1    Xiong, S.2    Hazra, S.3    Tsukamoto, H.4
  • 79
    • 0033672199 scopus 로고    scopus 로고
    • Molecular basis of transdifferentiation of pancreas to liver
    • Shen CN, Slack JM, Tosh D. 2000. Molecular basis of transdifferentiation of pancreas to liver. Nat Cell Biol 2:879-887.
    • (2000) Nat Cell Biol , vol.2 , pp. 879-887
    • Shen, C.N.1    Slack, J.M.2    Tosh, D.3
  • 80
    • 0037311162 scopus 로고    scopus 로고
    • Regeneration research today
    • Slack JM. 2003. Regeneration research today. Dev Dyn 226:162-166.
    • (2003) Dev Dyn , vol.226 , pp. 162-166
    • Slack, J.M.1
  • 82
    • 0037075991 scopus 로고    scopus 로고
    • Clinical practice. Barrett's esophagus
    • Spechler SJ. 2002. Clinical practice. Barrett's esophagus. N Engl J Med 346:836-842.
    • (2002) N Engl J Med , vol.346 , pp. 836-842
    • Spechler, S.J.1
  • 83
    • 0034785407 scopus 로고    scopus 로고
    • Transforming growth factor-beta, basement membrane, and epithelial-mesenchymal transdifferentiation: Implications for fibrosis in kidney disease
    • Stahl PJ, Felsen D. 2001. Transforming growth factor-beta, basement membrane, and epithelial-mesenchymal transdifferentiation: implications for fibrosis in kidney disease. Am J Pathol 159:1187-1192.
    • (2001) Am J Pathol , vol.159 , pp. 1187-1192
    • Stahl, P.J.1    Felsen, D.2
  • 85
    • 32844462637 scopus 로고    scopus 로고
    • Reprogramming liverstem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors
    • Tang DQ, Lu S, Sun YP, Rodrigues E, Chou W, Yang C, Cao LZ, Chang LJ, Yang LJ. 2006. Reprogramming liverstem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors. Lab Invest 86:83-93.
    • (2006) Lab Invest , vol.86 , pp. 83-93
    • Tang, D.Q.1    Lu, S.2    Sun, Y.P.3    Rodrigues, E.4    Chou, W.5    Yang, C.6    Cao, L.Z.7    Chang, L.J.8    Yang, L.J.9
  • 86
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM. 1994. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 79:1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 87
    • 0036517883 scopus 로고    scopus 로고
    • How cells change their phenotype
    • Tosh D, Slack JM. 2002. How cells change their phenotype. Nat Rev Mol Cell Biol 3:187-194.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 187-194
    • Tosh, D.1    Slack, J.M.2
  • 88
    • 0036725183 scopus 로고    scopus 로고
    • Differentiated properties of hepatocytes induced from pancreatic cells
    • Tosh D, Shen CN, Slack JM. 2002. Differentiated properties of hepatocytes induced from pancreatic cells. Hepatology 36:534-543.
    • (2002) Hepatology , vol.36 , pp. 534-543
    • Tosh, D.1    Shen, C.N.2    Slack, J.M.3
  • 90
    • 33747616182 scopus 로고    scopus 로고
    • Anti-adipogenic regulation underlies hepatic stellate cell transdifferentiation
    • Tsukamoto H, She H, Hazra S, Cheng J, Miyahara T. 2006. Anti-adipogenic regulation underlies hepatic stellate cell transdifferentiation. J Gastroenterol Hepatol 21(Suppl 3):S102-S105.
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.SUPPL. 3
    • Tsukamoto, H.1    She, H.2    Hazra, S.3    Cheng, J.4    Miyahara, T.5
  • 92
    • 0032500020 scopus 로고    scopus 로고
    • Regeneration in metazoan larvae
    • Vickery MS, McClintock JB. 1998. Regeneration in metazoan larvae. Nature 394: 140.
    • (1998) Nature , vol.394 , pp. 140
    • Vickery, M.S.1    McClintock, J.B.2
  • 93
    • 26444463776 scopus 로고    scopus 로고
    • Hepatocyte-like cells transdifferentiated from a pancreatic origin can support replication of hepatitis B virus
    • Wang RY, Shen CN, Lin MH, Tosh D, Shih C. 2005. Hepatocyte-like cells transdifferentiated from a pancreatic origin can support replication of hepatitis B virus. J Virol 79:13116-13128.
    • (2005) J Virol , vol.79 , pp. 13116-13128
    • Wang, R.Y.1    Shen, C.N.2    Lin, M.H.3    Tosh, D.4    Shih, C.5
  • 95
    • 0001067789 scopus 로고
    • The determination of characters in metamorphosis in Rhodnius prolixus (Hemiptera)
    • Wigglesworth VB. 1940. The determination of characters in metamorphosis in Rhodnius prolixus (Hemiptera). J Exp Biol 17:201-222.
    • (1940) J Exp Biol , vol.17 , pp. 201-222
    • Wigglesworth, V.B.1
  • 98
    • 0029927506 scopus 로고    scopus 로고
    • The non-human primate endocrine pancreas: Development, regeneration potential and metaplasia
    • Wolfe-Coote S, Louw J, Woodroof C, Du Toit DF. 1996. The non-human primate endocrine pancreas: development, regeneration potential and metaplasia. Cell Biol Int 20:95-101.
    • (1996) Cell Biol Int , vol.20 , pp. 95-101
    • Wolfe-Coote, S.1    Louw, J.2    Woodroof, C.3    Du Toit, D.F.4
  • 99
    • 34248654885 scopus 로고    scopus 로고
    • The impact of pregnane X receptor activation on liver fibrosis
    • Wright MC. 2006. The impact of pregnane X receptor activation on liver fibrosis. Biochem Soc Trans 34:1119-1123.
    • (2006) Biochem Soc Trans , vol.34 , pp. 1119-1123
    • Wright, M.C.1
  • 100
    • 2542455620 scopus 로고    scopus 로고
    • Stepwise reprogramming of B cells into macrophages
    • Xie H, Ye M, Feng R, Graf T. 2004. Stepwise reprogramming of B cells into macrophages. Cell 117:663-676.
    • (2004) Cell , vol.117 , pp. 663-676
    • Xie, H.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 101
    • 22144458692 scopus 로고    scopus 로고
    • Regenerative medicine of the pancreatic beta cells
    • Yamada S, Kojima I. 2005. Regenerative medicine of the pancreatic beta cells. J Hepatobiliary Pancreat Surg 12:218-226.
    • (2005) J Hepatobiliary Pancreat Surg , vol.12 , pp. 218-226
    • Yamada, S.1    Kojima, I.2
  • 102
    • 0021229461 scopus 로고
    • Conversion of iris epithelial cells as a model of differentiation control
    • Yamada T, McDevitt DS. 1984. Conversion of iris epithelial cells as a model of differentiation control. Differentiation 27:1-12.
    • (1984) Differentiation , vol.27 , pp. 1-12
    • Yamada, T.1    McDevitt, D.S.2
  • 104
    • 23244440980 scopus 로고    scopus 로고
    • Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus
    • Yu WY, Slack JM, Tosh D. 2005. Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus. Dev Biol 284:157-170.
    • (2005) Dev Biol , vol.284 , pp. 157-170
    • Yu, W.Y.1    Slack, J.M.2    Tosh, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.